152-95-4
基本信息
GENISTEIN-4'-GLUCOSIDE
GENISTEIN-4'-O-GLUCOSIDE
ISOGENISTIN
SOPHORICOSIDE
4'-beta-D-glucopyranosyloxy-5,7-dihydroxyisoflavone
5,7-Dihydroxy-3-[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]chromen-4-one
4H-1-Benzopyran-4-one,3-[4-(β-
D-glucopyranosyloxy)phenyl]-5,7-dihydroxy-
Sophoricoside ,98%
3-[4-(β-D-Glucopyranosyloxy)phenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one
物理化學(xué)性質(zhì)
應(yīng)用領(lǐng)域
常見問(wèn)題列表
Sophoricoside is an isoflavone glycoside isolated from Sophora japonica and has anti-inflammatory, anti-cancer and immunosuppressive effects. The results show that Sophoricoside (50 μM) significantly inhibits the PMACI-induced histamine release. The inhibition rate reaches up to 30.24%. The maximal rates of TNF-α, IL-8 and IL-6 inhibition by Sophoricoside (50 μM) are approximately 31.42%, 43.43% and 34.24%, respectively. The rates of the levels of Rel/p65 inhibition in nuclear by Sophoricoside (50 μM) is approximately 50.14%. Results show that the enhanced caspase-1 activity induced by PMACI is significantly reduced by Sophoricoside in a dose-dependent manner.
When the Sophoricoside is orally administered 1 h before compound 48/80 injections, the scratching behaviors is reduced. The inhibition rate of Sophoricoside (2 mg/kg) is approximately 41.21%. Orally administered Sophoricoside inhibits the scratching behaviors by 47.31%. When mice are treated for 2 weeks with Sophoricoside, the atopic dermatitis is recovered to a significant extent.
報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
2024/08/19 | HY-N0423 | 槐角苷 Sophoricoside | 152-95-4 | 100mg | 900元 |
2024/08/19 | HY-N0423 | 槐角苷 Sophoricoside | 152-95-4 | 10mM * 1mLin DMSO | 990元 |
2024/08/19 | XW080076 | 槐角苷 sophoricoside;5,7-dihydroxy-3-[4-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]chromen-4-one | 152-95-4 | 20MG | 222元 |