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ChemicalBook >> CAS DataBase List >> UNC2881

UNC2881

UNC2881 price.
  • $89 - $3600
  • Product name: UNC2881
  • CAS: 1493764-08-1
  • MF: C25H33N7O2
  • MW: 463.58
  • EINECS:
  • MDL Number:MFCD28142814
  • Synonyms:2-(Butylamino)-4-[(trans-4-hydroxycyclohexyl)amino]-N-[[4-(1H-imidazol-1-yl)phenyl]methyl]-5-pyrimidinecarboxamide;UNC2881;N-(4-(1H-iMidazol-1-yl)benzyl)-2-(butylaMino)-4-(((1r,4r)-4-hydroxycyclohexyl)aMino)pyriMidine-5-carboxaMide;N-(4-(1H-imidazol-1-yl)benzyl)-2-(butylamino)-4-((1r,4r)-4-hydroxycyclohexylamino)pyrimidine-5-carboxamide UNC2881;N-(4-(1H-Imidazol-1-yl)benzyl)-2-(butylamino)-4-(((1r,4r)-4-hydroxycyclohexyl)amino)pyrimidine;110849;UNC 2881; UNC-2881;CS-1177
24 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Tocris
  • TRC
Package
  • 5
  • 5mg
  • 2mg
  • 25
  • 25mg
  • 10mM(in 1mL DMSO)
  • 10mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2784AH
  • Product descriptionN-(4-(1H-Imidazol-1-yl)benzyl)-2-(butylamino)-4-(((1R,4R)-4-hydroxycyclohexyl)amino)pyrimidine-5-carboxamide
  • Packaging2mg
  • Price$142
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2784AH
  • Product descriptionN-(4-(1H-Imidazol-1-yl)benzyl)-2-(butylamino)-4-(((1R,4R)-4-hydroxycyclohexyl)amino)pyrimidine-5-carboxamide
  • Packaging10mg
  • Price$257
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4357
  • Product descriptionUNC2881
  • Packaging10mM(in 1mL DMSO)
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4357
  • Product descriptionUNC2881
  • Packaging10mg
  • Price$155
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4357
  • Product descriptionUNC2881
  • Packaging50mg
  • Price$635
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBU167099
  • Product descriptionUNC 2881
  • Packaging10mg
  • Price$155
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBU167099
  • Product descriptionUNC 2881
  • Packaging50mg
  • Price$542.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29012
  • Product descriptionUNC2881
  • Packaging50mg
  • Price$775
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29012
  • Product descriptionUNC2881
  • Packaging25mg
  • Price$414
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29012
  • Product descriptionUNC2881
  • Packaging10mg
  • Price$187
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29012
  • Product descriptionUNC2881
  • Packaging5mg
  • Price$106
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3255
  • Product descriptionUNC2881 99.91%
  • Packaging10mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3255
  • Product descriptionUNC2881 99.91%
  • Packaging50mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3255
  • Product descriptionUNC2881 99.91%
  • Packaging100mg
  • Price$750
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3255
  • Product descriptionUNC2881 99.91%
  • Packaging500mg
  • Price$2250
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003357
  • Product descriptionUNC2881 98+%
  • Packaging50mg
  • Price$825
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2784AH N-(4-(1H-Imidazol-1-yl)benzyl)-2-(butylamino)-4-(((1R,4R)-4-hydroxycyclohexyl)amino)pyrimidine-5-carboxamide 2mg $142 2021-12-16 Buy
AK Scientific 2784AH N-(4-(1H-Imidazol-1-yl)benzyl)-2-(butylamino)-4-(((1R,4R)-4-hydroxycyclohexyl)amino)pyrimidine-5-carboxamide 10mg $257 2021-12-16 Buy
ApexBio Technology B4357 UNC2881 10mM(in 1mL DMSO) $150 2021-12-16 Buy
ApexBio Technology B4357 UNC2881 10mg $155 2021-12-16 Buy
ApexBio Technology B4357 UNC2881 50mg $635 2021-12-16 Buy
Biosynth Carbosynth BU167099 UNC 2881 10mg $155 2021-12-16 Buy
Biosynth Carbosynth BU167099 UNC 2881 50mg $542.5 2021-12-16 Buy
Cayman Chemical 29012 UNC2881 50mg $775 2024-03-01 Buy
Cayman Chemical 29012 UNC2881 25mg $414 2024-03-01 Buy
Cayman Chemical 29012 UNC2881 10mg $187 2024-03-01 Buy
Cayman Chemical 29012 UNC2881 5mg $106 2024-03-01 Buy
ChemScene CS-3255 UNC2881 99.91% 10mg $140 2021-12-16 Buy
ChemScene CS-3255 UNC2881 99.91% 50mg $450 2021-12-16 Buy
ChemScene CS-3255 UNC2881 99.91% 100mg $750 2021-12-16 Buy
ChemScene CS-3255 UNC2881 99.91% 500mg $2250 2021-12-16 Buy
Crysdot CD31003357 UNC2881 98+% 50mg $825 2021-12-16 Buy

Properties

Density :1.31±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥13.55 mg/mL in DMSO
form :solid
pka :12.70±0.46(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

UNC2881 is an inhibitor of Mer (IC50 = 4.3 nM), a member of the TAM family of receptor tyrosine kinases. It is selective for Mer over the remaining TAM family members Axl and TYRO3 (IC50s = 360 and 250 nM, respectively). UNC2881 inhibits phosphorylation of Mer in 697 B-ALL acute lymphoblastic leukemia cells (IC50 = 21.9 nM). It inhibits platelet aggregation and ATP release induced by type I equine fibrillar collagen in isolated human platelet-rich plasma when used at a concentration of 3 μM.

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