Afatinib (BIBW 2992)
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- $24 - $2658.8
- Product name: Afatinib (BIBW 2992)
- CAS: 439081-18-2
- MF: C24H25ClFN5O3
- MW: 485.94
- EINECS:1308068-626-2
- MDL Number:MFCD12407405
- Synonyms:Tovok;Afatinb;(S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dim;Tovok, BIBW 2992;BIBW 2992;TOVOK;BIBW2992 Afatinib;Afatinib (BIBW 2992);ToMtovok
34 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- DC Chemicals
- Matrix Scientific
- TRC
Package
- 1unit
- 5mg
- 1mg
- 10mM(in 1mL DMSO)
- 10MG
- 20mg
- 25MG
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- 2g
- 5G
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1100-M001
- Product descriptionAfatinib ≥95%
- Packaging1mg
- Price$86
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7366
- Product descriptionAfatinib
- Packaging100mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7366
- Product descriptionAfatinib
- Packaging1g
- Price$285
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA369713
- Product description(S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide 98+%
- Packaging1g
- Price$51
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA369713
- Product description(S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide 98+%
- Packaging250mg
- Price$24
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0045864
- Product descriptionAFATINIB 95.00%
- Packaging10MG
- Price$701.2
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0045864
- Product descriptionAFATINIB 95.00%
- Packaging25MG
- Price$824.9
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8247
- Product descriptionAfatinib(BIBW2992)
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8247
- Product descriptionAfatinib(BIBW2992)
- Packaging5mg
- Price$52
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8247
- Product descriptionAfatinib(BIBW2992)
- Packaging10mM(in 1mL DMSO)
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8247
- Product descriptionAfatinib(BIBW2992)
- Packaging10mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8247
- Product descriptionAfatinib(BIBW2992)
- Packaging50mg
- Price$122
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60034
- Product descriptionAfatinib(BIBW2992)
- Packaging20mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb61181
- Product descriptionAfatinib, Free Base >99% pure
- Packaging25mg
- Price$323
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb61181
- Product descriptionAfatinib, Free Base >99% pure
- Packaging50mg
- Price$368.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb61181
- Product descriptionAfatinib, Free Base >99% pure
- Packaging100mg
- Price$374
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | SYN-1100-M001 | Afatinib ≥95% | 1mg | $86 | 2021-12-16 | Buy |
| AK Scientific | X7366 | Afatinib | 100mg | $80 | 2021-12-16 | Buy |
| AK Scientific | X7366 | Afatinib | 1g | $285 | 2021-12-16 | Buy |
| Ambeed | A369713 | (S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide 98+% | 1g | $51 | 2021-12-16 | Buy |
| Ambeed | A369713 | (S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide 98+% | 250mg | $24 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0045864 | AFATINIB 95.00% | 10MG | $701.2 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0045864 | AFATINIB 95.00% | 25MG | $824.9 | 2021-12-16 | Buy |
| ApexBio Technology | A8247 | Afatinib(BIBW2992) | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A8247 | Afatinib(BIBW2992) | 5mg | $52 | 2021-12-16 | Buy |
| ApexBio Technology | A8247 | Afatinib(BIBW2992) | 10mM(in 1mL DMSO) | $75 | 2021-12-16 | Buy |
| ApexBio Technology | A8247 | Afatinib(BIBW2992) | 10mg | $85 | 2021-12-16 | Buy |
| ApexBio Technology | A8247 | Afatinib(BIBW2992) | 50mg | $122 | 2021-12-16 | Buy |
| Arctom | CFN60034 | Afatinib(BIBW2992) | 20mg | $70 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb61181 | Afatinib, Free Base >99% pure | 25mg | $323 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb61181 | Afatinib, Free Base >99% pure | 50mg | $368.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb61181 | Afatinib, Free Base >99% pure | 100mg | $374 | 2021-12-16 | Buy |
Properties
Boiling point :676.9±55.0 °C(Predicted)
Density :1.380
storage temp. :Store at -20°C
solubility :≥24.3 mg/mL in DMSO; insoluble in H2O; ≥42.1 mg/mL in EtOH with ultrasonic
form :solid
pka :12.06±0.43(Predicted)
color :White to off-white
CAS DataBase Reference :439081-18-2
Density :1.380
storage temp. :Store at -20°C
solubility :≥24.3 mg/mL in DMSO; insoluble in H2O; ≥42.1 mg/mL in EtOH with ultrasonic
form :solid
pka :12.06±0.43(Predicted)
color :White to off-white
CAS DataBase Reference :439081-18-2
Safety Information
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Description
BIBW 2992 is an anilino-quinazoline that irreversibly inhibits EGFR and HER2 kinase activity in cell-free in vitro kinase assays (IC50s = 0.5 and 14 nM, respectively). It demonstrates potent activity against mutant forms of EGFR and HER2, including erlotinib-resistant isoforms (IC50 = 10 nM), and displays weak activity when evaluated against a panel of 52 additional tyrosine and serine/threonine kinases. BIBW 2992 suppresses transformation in isogenic cell-based assays, inhibits survival of cancer cell lines, and at 20 mg/kg, induces tumor regression in xenograft and transgenic lung cancer models.More related product prices
Erlotinib hydrochloride 871700-17-3 Gefitinib Bortezomib Lapatinib 4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]- 162012-69-3 86087-23-2 BIBW2992 DiMaleate 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- Afatinib (S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diaMine trans-4-Dimethylaminocrotonic acid hydrochloride Vandetanib Lenvatinib AP26113 AZD-9291Related product price
- Erlotinib hydrochloride
$5-3498.6 - 871700-17-3
$28-4391.1 - Gefitinib
$5-1141
Suppliers and manufacturers
Capot Chemical Co.,Ltd.
Beijing Cooperate Pharmaceutical Co.,Ltd
Shanghai Bojing Chemical Co.,Ltd.
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
Shanghai Yingrui Biopharma Co., Ltd.
