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ChemicalBook >> CAS DataBase List >> 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- price.
  • $8 - $1428
  • Product name: 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-
  • CAS: 162012-67-1
  • MF: C14H7ClF2N4O2
  • MW: 336.68
  • EINECS:-0
  • MDL Number:MFCD09998825
  • Synonyms:4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-;4-(3-chloro-4-fiuoro-phen...;N-(3-chloro-4-fluorophenyl)-N-(7-fluoro-6-nitroquinazolin-4-yl)acetaMide;(3-Chloro-4-fluorophenyl)(7-fluoro-6-nitroquinazolin-4-yl)amine;Afatinib intermediate A;3-Chloro-4-fluorophenyl)(7-fluoro-6-nitroquinazolin-4-yl);N-(3-chloro-4-fluorophenyl)-7-fiuoro-6-nitro-4-quinazolinaMine;N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine (3-Chloro-4-fluorophenyl)(7-fluoro-6-nitroquinazolin-4-yl)amine
32 prices
Selected condition：
Brand
  • Acrotein
  • AK Scientific
  • Alichem
  • Ambeed
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Chemcia Scientific
  • ChemScene
  • Crysdot
  • Matrix Scientific
  • SynQuest Laboratories
  • TCI Chemical
  • TRC
Package
  • 100mg
  • 250mg
  • 1g
  • 2g
  • 5g
  • 10g
  • 25g
  • 50G
  • 100g
  • 500g
  • ManufacturerAcrotein
  • Product numberH-7570
  • Product descriptionN-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine 97%
  • Packaging25g
  • Price$182.97
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberB693
  • Product description4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline
  • Packaging5g
  • Price$98
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number162012671
  • Product descriptionN-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
  • Packaging500g
  • Price$570
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number162012671
  • Product descriptionN-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
  • Packaging100g
  • Price$247.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA257382
  • Product descriptionN-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine 98%
  • Packaging1g
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA257382
  • Product descriptionN-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine 98%
  • Packaging5g
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA257382
  • Product descriptionN-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine 98%
  • Packaging10g
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA257382
  • Product descriptionN-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine 98%
  • Packaging25g
  • Price$61
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA257382
  • Product descriptionN-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine 98%
  • Packaging100g
  • Price$228
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA257382
  • Product descriptionN-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine 98%
  • Packaging500g
  • Price$743
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0049893
  • Product description3-CHLORO-4-FLUOROPHENYL)(7-FLUORO-6-NITROQUINAZOLIN-4-YL)AMINE 95.00%
  • Packaging25G
  • Price$480.9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0049893
  • Product description3-CHLORO-4-FLUOROPHENYL)(7-FLUORO-6-NITROQUINAZOLIN-4-YL)AMINE 95.00%
  • Packaging50G
  • Price$692.17
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC40533
  • Product description4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline
  • Packaging2g
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC40533
  • Product description4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline
  • Packaging5G
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC40533
  • Product description4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline
  • Packaging10g
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC40533
  • Product description4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline
  • Packaging25g
  • Price$285
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Acrotein H-7570 N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine 97% 25g $182.97 2021-12-16 Buy
AK Scientific B693 4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline 5g $98 2021-12-16 Buy
Alichem 162012671 N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine 500g $570 2021-12-16 Buy
Alichem 162012671 N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine 100g $247.5 2021-12-16 Buy
Ambeed A257382 N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine 98% 1g $8 2021-12-16 Buy
Ambeed A257382 N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine 98% 5g $20 2021-12-16 Buy
Ambeed A257382 N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine 98% 10g $30 2021-12-16 Buy
Ambeed A257382 N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine 98% 25g $61 2021-12-16 Buy
Ambeed A257382 N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine 98% 100g $228 2021-12-16 Buy
Ambeed A257382 N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine 98% 500g $743 2021-12-16 Buy
American Custom Chemicals Corporation HCH0049893 3-CHLORO-4-FLUOROPHENYL)(7-FLUORO-6-NITROQUINAZOLIN-4-YL)AMINE 95.00% 25G $480.9 2021-12-16 Buy
American Custom Chemicals Corporation HCH0049893 3-CHLORO-4-FLUOROPHENYL)(7-FLUORO-6-NITROQUINAZOLIN-4-YL)AMINE 95.00% 50G $692.17 2021-12-16 Buy
Biosynth Carbosynth FC40533 4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline 2g $65 2021-12-16 Buy
Biosynth Carbosynth FC40533 4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline 5G $100 2021-12-16 Buy
Biosynth Carbosynth FC40533 4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline 10g $180 2021-12-16 Buy
Biosynth Carbosynth FC40533 4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline 25g $285 2021-12-16 Buy

Properties

Melting point :242-244℃
Boiling point :489℃
Density :1.616
Flash point :249℃
storage temp. :2-8°C(protect from light)
solubility :DMSO (Slightly), Methanol (Slightly, Sonicated)
form :Solid
pka :5.07±0.70(Predicted)
color :Yellow to Dark Yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline is an intermediate in the synthesis of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.