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ChemicalBook >> CAS DataBase List >> UNC0379

UNC0379

UNC0379 price.
  • $74 - $1600
  • Product name: UNC0379
  • CAS: 1620401-82-2
  • MF: C23H35N5O2
  • MW: 413.56
  • EINECS:
  • MDL Number:MFCD28167817
  • Synonyms:UNC0379;6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine;6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine UNC0379;UNC0379, >=98%;UNC03;6,7-Dimethoxy-2-(1-pyrrolidinyl)-N-[5-(1-pyrrolidinyl)pentyl]-4-quinazolinamine;UNC0379, UNC-0379, UNC 0379;UNC 0379; UNC-0379
27 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberSYN5081
  • Product descriptionUNC0379
  • Packaging100mg
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA211708
  • Product description6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine 98+%
  • Packaging5mg
  • Price$74
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA211708
  • Product description6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine 98+%
  • Packaging10mg
  • Price$111
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA211708
  • Product description6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine 98+%
  • Packaging100mg
  • Price$539
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB8009
  • Product descriptionUNC0379
  • Packaging5mg
  • Price$158
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB8009
  • Product descriptionUNC0379
  • Packaging10mg
  • Price$213
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB8009
  • Product descriptionUNC0379
  • Packaging50mg
  • Price$638
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB8009
  • Product descriptionUNC0379
  • Packaging100mg
  • Price$922
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS479253
  • Product description6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine
  • Packaging100mg
  • Price$534
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2418
  • Product descriptionUNC0379 98%
  • Packaging10mg
  • Price$137.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2418
  • Product descriptionUNC0379 98%
  • Packaging50mg
  • Price$495
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546260
  • Product descriptionUNC-0379 >98%
  • Packaging5mg
  • Price$181.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546260
  • Product descriptionUNC-0379 >98%
  • Packaging25mg
  • Price$430.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFU137732
  • Product descriptionUNC 0379 NEW
  • Packaging10mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFU137732
  • Product descriptionUNC 0379 NEW
  • Packaging50mg
  • Price$275
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16400
  • Product descriptionUNC0379 ≥95%
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5081 UNC0379 100mg $700 2021-12-16 Buy
Ambeed A211708 6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine 98+% 5mg $74 2021-12-16 Buy
Ambeed A211708 6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine 98+% 10mg $111 2021-12-16 Buy
Ambeed A211708 6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine 98+% 100mg $539 2021-12-16 Buy
ApexBio Technology B8009 UNC0379 5mg $158 2021-12-16 Buy
ApexBio Technology B8009 UNC0379 10mg $213 2021-12-16 Buy
ApexBio Technology B8009 UNC0379 50mg $638 2021-12-16 Buy
ApexBio Technology B8009 UNC0379 100mg $922 2021-12-16 Buy
Arctom AS479253 6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine 100mg $534 2021-12-16 Buy
Axon Medchem Axon2418 UNC0379 98% 10mg $137.5 2021-12-16 Buy
Axon Medchem Axon2418 UNC0379 98% 50mg $495 2021-12-16 Buy
Biorbyt Ltd orb546260 UNC-0379 >98% 5mg $181.9 2021-12-16 Buy
Biorbyt Ltd orb546260 UNC-0379 >98% 25mg $430.1 2021-12-16 Buy
Biosynth Carbosynth FU137732 UNC 0379 NEW 10mg $95 2021-12-16 Buy
Biosynth Carbosynth FU137732 UNC 0379 NEW 50mg $275 2021-12-16 Buy
Cayman Chemical 16400 UNC0379 ≥95% 5mg $93 2024-03-01 Buy

Properties

Boiling point :606.3±65.0 °C(Predicted)
Density :1.168±0.06 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :Soluble in DMSO (up to 30 mg/ml)
pka :10.54±0.20(Predicted)
form :solid
color :Tan
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

SET domain-containing protein 8 (SET8) is a methyltransferase that selectively mono-methylates histone H4 at lysine residue 20, an event proven to have an important role in chromatin structure and transcriptional activation. It is also a regulator of p53, mono-methylating lysine 382 of the tumor suppressor. UNC0379 is a substrate-competitive inhibitor of the lysine methyltransferase SET8 (IC50 = 7.3 μM; Kd = 18.3 μM). It is selective for SET8 over 15 other methyltransferases, including G9a and GLP (IC50s = >100 μM).

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