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ChemicalBook >> CAS DataBase List >> UNC3866

UNC3866

UNC3866 price.
  • $48 - $1620
  • Product name: UNC3866
  • CAS: 1872382-47-2
  • MF: C43H66N6O8
  • MW: 795.02
  • EINECS:-0
  • MDL Number:MFCD30536205
  • Synonyms:UNC3866;N-[4-(1,1-Dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-L-serine methyl ester;CS-2491;UNC 3866;UNC-3866;(3S,6S,9S,12S,15S)-Methyl 3-benzyl-1-(4-(tert-butyl)phenyl)-12-(4-(diethylamino)butyl)-15-(hydroxymethyl)-9-isobutyl-6-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecan-16-oate;L-Serine, N-[4-(1,1-dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-, methyl ester;UNC3866,inhibit,Histone Methyltransferase,UNC-3866,Inhibitor,UNC 3866
21 prices
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  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number4495ED
  • Product descriptionMethyl(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(4-tert-butylbenzoyl)amino]-3-phenylpropanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]-6-(diethylamino)hexanoyl]amino]-3-hydroxypropanoate
  • Packaging5mg
  • Price$267
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA718589
  • Product description(3S,6S,9S,12S,15S)-Methyl3-benzyl-1-(4-(tert-butyl)phenyl)-12-(4-(diethylamino)butyl)-15-(hydroxymethyl)-9-isobutyl-6-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecan-16-oate 99+%
  • Packaging5mg
  • Price$437
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA718589
  • Product description(3S,6S,9S,12S,15S)-Methyl3-benzyl-1-(4-(tert-butyl)phenyl)-12-(4-(diethylamino)butyl)-15-(hydroxymethyl)-9-isobutyl-6-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecan-16-oate 99+%
  • Packaging10mg
  • Price$567
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA718589
  • Product description(3S,6S,9S,12S,15S)-Methyl3-benzyl-1-(4-(tert-butyl)phenyl)-12-(4-(diethylamino)butyl)-15-(hydroxymethyl)-9-isobutyl-6-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecan-16-oate 99+%
  • Packaging25mg
  • Price$736
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA718589
  • Product description(3S,6S,9S,12S,15S)-Methyl3-benzyl-1-(4-(tert-butyl)phenyl)-12-(4-(diethylamino)butyl)-15-(hydroxymethyl)-9-isobutyl-6-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecan-16-oate 99+%
  • Packaging50mg
  • Price$956
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA718589
  • Product description(3S,6S,9S,12S,15S)-Methyl3-benzyl-1-(4-(tert-butyl)phenyl)-12-(4-(diethylamino)butyl)-15-(hydroxymethyl)-9-isobutyl-6-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecan-16-oate 99+%
  • Packaging100mg
  • Price$1242
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA8725
  • Product descriptionUNC3866
  • Packaging2mg
  • Price$126
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA8725
  • Product descriptionUNC3866
  • Packaging5mg
  • Price$189
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA8725
  • Product descriptionUNC3866
  • Packaging10mg
  • Price$331
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8725
  • Product descriptionUNC3866
  • Packaging25mg
  • Price$614
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19237
  • Product descriptionUNC3866 ≥95%
  • Packaging1mg
  • Price$48
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number19237
  • Product descriptionUNC3866 ≥95%
  • Packaging5mg
  • Price$152
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19237
  • Product descriptionUNC3866 ≥95%
  • Packaging10mg
  • Price$278
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19237
  • Product descriptionUNC3866 ≥95%
  • Packaging25mg
  • Price$578
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6101
  • Product descriptionUNC3866 >98.0%
  • Packaging5mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6101
  • Product descriptionUNC3866 >98.0%
  • Packaging10mg
  • Price$252
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4495ED Methyl(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(4-tert-butylbenzoyl)amino]-3-phenylpropanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]-6-(diethylamino)hexanoyl]amino]-3-hydroxypropanoate 5mg $267 2021-12-16 Buy
Ambeed A718589 (3S,6S,9S,12S,15S)-Methyl3-benzyl-1-(4-(tert-butyl)phenyl)-12-(4-(diethylamino)butyl)-15-(hydroxymethyl)-9-isobutyl-6-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecan-16-oate 99+% 5mg $437 2021-12-16 Buy
Ambeed A718589 (3S,6S,9S,12S,15S)-Methyl3-benzyl-1-(4-(tert-butyl)phenyl)-12-(4-(diethylamino)butyl)-15-(hydroxymethyl)-9-isobutyl-6-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecan-16-oate 99+% 10mg $567 2021-12-16 Buy
Ambeed A718589 (3S,6S,9S,12S,15S)-Methyl3-benzyl-1-(4-(tert-butyl)phenyl)-12-(4-(diethylamino)butyl)-15-(hydroxymethyl)-9-isobutyl-6-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecan-16-oate 99+% 25mg $736 2021-12-16 Buy
Ambeed A718589 (3S,6S,9S,12S,15S)-Methyl3-benzyl-1-(4-(tert-butyl)phenyl)-12-(4-(diethylamino)butyl)-15-(hydroxymethyl)-9-isobutyl-6-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecan-16-oate 99+% 50mg $956 2021-12-16 Buy
Ambeed A718589 (3S,6S,9S,12S,15S)-Methyl3-benzyl-1-(4-(tert-butyl)phenyl)-12-(4-(diethylamino)butyl)-15-(hydroxymethyl)-9-isobutyl-6-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecan-16-oate 99+% 100mg $1242 2021-12-16 Buy
ApexBio Technology A8725 UNC3866 2mg $126 2021-12-16 Buy
ApexBio Technology A8725 UNC3866 5mg $189 2021-12-16 Buy
ApexBio Technology A8725 UNC3866 10mg $331 2021-12-16 Buy
ApexBio Technology A8725 UNC3866 25mg $614 2021-12-16 Buy
Cayman Chemical 19237 UNC3866 ≥95% 1mg $48 2024-03-01 Buy
Cayman Chemical 19237 UNC3866 ≥95% 5mg $152 2024-03-01 Buy
Cayman Chemical 19237 UNC3866 ≥95% 10mg $278 2024-03-01 Buy
Cayman Chemical 19237 UNC3866 ≥95% 25mg $578 2024-03-01 Buy
ChemScene CS-6101 UNC3866 >98.0% 5mg $144 2021-12-16 Buy
ChemScene CS-6101 UNC3866 >98.0% 10mg $252 2021-12-16 Buy

Properties

Boiling point :1034.5±65.0 °C(Predicted)
Density :1.129±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO
form :A crystalline solid
pka :13.39±0.46(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

UNC3866 is an inhibitor of chromobox homolog 7 (CBX7; Kd = 97 nM). It also binds to CBX4 (Kd = 94 nM) but is greater than 6-fold selective over CBX2, 6, and 8 and the chromodomain Y family (CDY) chromodomains CDY1, L1b, and L2 (Kds = 0.61-6.3 μM). UNC3866 pretreatment (30 μM) of PC3 lysates completely inhibits chemiprecipitation of CBX7. It induces a senescent-like morphology and reduces growth of PC3 cells with an EC50 value of 7.6 μM.

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