UNC-1215
- $22 - $5390
- Product name: UNC-1215
- CAS: 1415800-43-9
- MF: C32H43N5O2
- MW: 529.72
- EINECS:
- MDL Number:MFCD22683289
- Synonyms:UNC 1215;UNC1215;UNC-1215;(2-(phenylaMino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)Methanone);1,1'-[2-(Phenylamino)-1,4-phenylene]bis[1-[4-(1-pyrrolidinyl)-1-piperidinyl]methanone];UNC 1215, >=98%;UNC1215 1,1'-[2-(PhenylaMino)-1,4-phenylene]bis[1-[4-(1-pyrrolidinyl)-1-piperidinyl]Methanone];Methanone, 1,1'-[2-(phenylamino)-1,4-phenylene]bis[1-[4-(1-pyrrolidinyl)-1-piperidinyl]-
38 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Apolloscientific
- Biorbyt Ltd
- BroadPharm
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- SynQuest Laboratories
- Tocris
- TRC
Package
- 50
- 1mg
- 5mg
- 10
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 10mM(in 1mL DMSO)
- 1000mg
- ManufacturerAK Scientific
- Product numberSYN5455
- Product descriptionUNC1215
- Packaging50mg
- Price$547
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA255611
- Product descriptionUNC1215 98+%
- Packaging1mg
- Price$22
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA255611
- Product descriptionUNC1215 98+%
- Packaging5mg
- Price$38
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA255611
- Product descriptionUNC1215 98+%
- Packaging10mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA255611
- Product descriptionUNC1215 98+%
- Packaging50mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA255611
- Product descriptionUNC1215 98+%
- Packaging100mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA255611
- Product descriptionUNC1215 98+%
- Packaging250mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3901
- Product descriptionUNC1215
- Packaging5mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3901
- Product descriptionUNC1215
- Packaging10mM(in 1mL DMSO)
- Price$93
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3901
- Product descriptionUNC1215
- Packaging10mg
- Price$105
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3901
- Product descriptionUNC1215
- Packaging50mg
- Price$410
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberOR323195
- Product description(2-(Phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone)
- Packaging100mg
- Price$805
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181178
- Product descriptionUNC-1215 >98%
- Packaging1000mg
- Price$2691.1
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181178
- Product descriptionUNC-1215 >98%
- Packaging250mg
- Price$1356.6
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181178
- Product descriptionUNC-1215 >98%
- Packaging100mg
- Price$690.2
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-21087
- Product description(2-(phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone)
- Packaging100mg
- Price$385
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | SYN5455 | UNC1215 | 50mg | $547 | 2021-12-16 | Buy |
Ambeed | A255611 | UNC1215 98+% | 1mg | $22 | 2021-12-16 | Buy |
Ambeed | A255611 | UNC1215 98+% | 5mg | $38 | 2021-12-16 | Buy |
Ambeed | A255611 | UNC1215 98+% | 10mg | $50 | 2021-12-16 | Buy |
Ambeed | A255611 | UNC1215 98+% | 50mg | $85 | 2021-12-16 | Buy |
Ambeed | A255611 | UNC1215 98+% | 100mg | $110 | 2021-12-16 | Buy |
Ambeed | A255611 | UNC1215 98+% | 250mg | $218 | 2021-12-16 | Buy |
ApexBio Technology | A3901 | UNC1215 | 5mg | $70 | 2021-12-16 | Buy |
ApexBio Technology | A3901 | UNC1215 | 10mM(in 1mL DMSO) | $93 | 2021-12-16 | Buy |
ApexBio Technology | A3901 | UNC1215 | 10mg | $105 | 2021-12-16 | Buy |
ApexBio Technology | A3901 | UNC1215 | 50mg | $410 | 2021-12-16 | Buy |
Apolloscientific | OR323195 | (2-(Phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone) | 100mg | $805 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181178 | UNC-1215 >98% | 1000mg | $2691.1 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181178 | UNC-1215 >98% | 250mg | $1356.6 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181178 | UNC-1215 >98% | 100mg | $690.2 | 2021-12-16 | Buy |
BroadPharm | BP-21087 | (2-(phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone) | 100mg | $385 | 2021-12-16 | Buy |
Properties
Boiling point :712.1±60.0 °C(Predicted)
Density :1.224±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear
pka :9.90±0.20(Predicted)
form :powder
color :white to beige
Density :1.224±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear
pka :9.90±0.20(Predicted)
form :powder
color :white to beige
Safety Information
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Description
Methyllysine (Kme) recognition “reader” domains play a central role in epigenetic regulation during cellular differentiation, development, and gene transcription. UNC1215 is a potent and selective chemical probe for the Kme reading function of L3MBTL3, a member of the malignant brain tumor (MBT) family of chromatin interacting transcriptional repressors. UNC1215 binds L3MBTL3 with a Kd value of 120 nM (IC50 = 40 nM), competitively displacing mono- or dimethyl-lysine containing peptides. This probe is greater than 50-fold selective toward L3MBTL3 than other members of the human MBT family and demonstrates selectivity against more than 200 other Kme reader domains examined. See the Structural Genomics Consortium (SGC) website for more information.Related product price
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