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ChemicalBook >> CAS DataBase List >> NLG919

NLG919

NLG919 price.
  • $37 - $1208.7
  • Product name: NLG919
  • CAS: 1402836-58-1
  • MF: C18H22N2O
  • MW: 282.38
  • EINECS:1592732-453-0
  • MDL Number:MFCD26142661
  • Synonyms:NLG919;1-CYCLOHEXYL-2-(5H-IMIDAZO[5,1-A]ISOINDOL-5-YL)ETHANOL;5H-Imidazo[5,1-a]isoindole-5-ethanol, α-cyclohexyl-;1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol NLG919;NLG919 1-CYCLOHEXYL-2-(5H-IMIDAZO[5,1-A]ISOINDOL-5-YL)ETHANOL;alpha-Cyclohexyl-5H-imidazo[5,1-a]isoindole-5-ethanol;NLG919, >=98%;NLG919;NLG-919
22 prices
Selected condition：
Brand
  • Abosyn
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 500mg
  • 1g
  • 10mM(in 1mL DMSO)
  • 0.25g
  • 250mg
  • ManufacturerAbosyn
  • Product number61-0041
  • Product description1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol 95-98%
  • Packaging0.25g
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerAbosyn
  • Product number61-0041
  • Product description1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol 95-98%
  • Packaging1g
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4373
  • Product descriptionNLG919
  • Packaging10mM(in 1mL DMSO)
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146279
  • Product descriptionNLG919(GDC-0919) >99%
  • Packaging100mg
  • Price$414.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146279
  • Product descriptionNLG919(GDC-0919) >99%
  • Packaging250mg
  • Price$615.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146279
  • Product descriptionNLG919(GDC-0919) >99%
  • Packaging1g
  • Price$1208.7
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21509
  • Product descriptionNLG-919 ≥98% (mixture of enantiomers)
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21509
  • Product descriptionNLG-919 ≥98% (mixture of enantiomers)
  • Packaging5mg
  • Price$98
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21509
  • Product descriptionNLG-919 ≥98% (mixture of enantiomers)
  • Packaging10mg
  • Price$178
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21509
  • Product descriptionNLG-919 ≥98% (mixture of enantiomers)
  • Packaging25mg
  • Price$397
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3512
  • Product descriptionIDO-IN-7 99.87%
  • Packaging10mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3512
  • Product descriptionIDO-IN-7 99.87%
  • Packaging50mg
  • Price$288
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3512
  • Product descriptionIDO-IN-7 99.87%
  • Packaging100mg
  • Price$504
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003612
  • Product descriptionNLG919 98+%
  • Packaging50mg
  • Price$228
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003612
  • Product descriptionNLG919 98+%
  • Packaging100mg
  • Price$399
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC5172
  • Product descriptionNLG919(GDC-0919) >99%
  • Packaging1g
  • Price$800
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Abosyn 61-0041 1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol 95-98% 0.25g $300 2021-12-16 Buy
Abosyn 61-0041 1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol 95-98% 1g $700 2021-12-16 Buy
ApexBio Technology A4373 NLG919 10mM(in 1mL DMSO) $115 2021-12-16 Buy
Biorbyt Ltd orb146279 NLG919(GDC-0919) >99% 100mg $414.8 2021-12-16 Buy
Biorbyt Ltd orb146279 NLG919(GDC-0919) >99% 250mg $615.4 2021-12-16 Buy
Biorbyt Ltd orb146279 NLG919(GDC-0919) >99% 1g $1208.7 2021-12-16 Buy
Cayman Chemical 21509 NLG-919 ≥98% (mixture of enantiomers) 1mg $37 2024-03-01 Buy
Cayman Chemical 21509 NLG-919 ≥98% (mixture of enantiomers) 5mg $98 2024-03-01 Buy
Cayman Chemical 21509 NLG-919 ≥98% (mixture of enantiomers) 10mg $178 2024-03-01 Buy
Cayman Chemical 21509 NLG-919 ≥98% (mixture of enantiomers) 25mg $397 2024-03-01 Buy
ChemScene CS-3512 IDO-IN-7 99.87% 10mg $108 2021-12-16 Buy
ChemScene CS-3512 IDO-IN-7 99.87% 50mg $288 2021-12-16 Buy
ChemScene CS-3512 IDO-IN-7 99.87% 100mg $504 2021-12-16 Buy
Crysdot CD31003612 NLG919 98+% 50mg $228 2021-12-16 Buy
Crysdot CD31003612 NLG919 98+% 100mg $399 2021-12-16 Buy
DC Chemicals DC5172 NLG919(GDC-0919) >99% 1g $800 2021-12-16 Buy

Properties

Melting point :143 - 146°C
Boiling point :524.6±33.0 °C(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 15 mg/ml)
pka :14.85±0.20(Predicted)
form :solid
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

(±)-NLG-919 is an indoleamine 2,3-dioxygenase (IDO) pathway inhibitor (Ki = 7 nM; EC50 = 75 nM). (±)-NLG-919 inhibits IDO-induced T cell suppression and restores T cell response during allogenic mixed lymphocyte reactions in vitro (ED50s = 80 and 120 nM, respectively). In vivo, (±)-NLG-919 induces a 95% reduction in tumor volume when administered in conjunction with a pmel-1 T cell vaccine. Formulations containing (±)-NLG-919 are under investigation in clinical trials for treatment of glioblastoma, melanoma, pancreatic, and breast cancers.

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