IDO-IN-7 NEW
| Price | $58 | $95 | $153 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-17 |
Product Details
| Product Name: IDO-IN-7 | CAS No.: 1402836-58-1 |
| Purity: 99.85% | Supply Ability: 10g |
| Release date: 2024/11/17 |
Product Introduction
Bioactivity
| 名稱 | IDO-IN-7 |
| 描述 | IDO-IN-7 (NLG-919 analogue) is a potent inhibitor of the IDO (indoleamine-(2, 3)-dioxygenase) pathway. |
| 體外活性 | In mice bearing B16F10 tumors, NLG919 significantly enhanced the antitumor response of pmel-1 resting cells to homologous hgp100 peptide and CpG-1826. |
| 體內(nèi)活性 | NLG919 effectively blocks the IDO-induced suppression of T-cell responses, restoring T-cell activity (ED50=80 nM). In mouse dendritic cells (DCs) expressing IDO from tumor lymph nodes (ED50=120 nM), NLG919 abolishes the IDO-induced inhibition of antigen-specific T-cells (OT-1). |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | Ethanol : 26 mg/mL (92.1 mM) DMSO : 45 mg/mL (159.36 mM) H2O : < 1 mg/mL (insoluble or slightly soluble) |
| 關鍵字 | NLG919 analogue | NLG-919 | NLG 919 | Inhibitor | inhibit | Indoleamine 2,3-Dioxygenase (IDO) | IDO-IN-7 | IDOIN7 | IDO IN 7 | GDC0919 | GDC 0919 |
| 相關產(chǎn)品 | Palmatine chloride | IDO-IN-1 | GNF-PF-3777 | Coptisine chloride | Necrostatin-1 | Coptisine sulfate | Indoximod | Palmatine | IDO inhibitor 1 | Epacadostat | IDO5L | IDO-IN-12 |
| 相關庫 | 經(jīng)典已知活性庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | 代謝化合物庫 | 臨床期小分子藥物庫 | 已知活性化合物庫 | 人代謝物化合物庫 | 抗癌活性化合物庫 | 抗癌藥物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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