| Identification | More | [Name]
3-(Aminomethyl)pyridine | [CAS]
3731-52-0 | [Synonyms]
3-(AMINOMETHYL)PYRIDINE
3AMPY
3-PICOLYLAMINE
3-PYRIDINEMETHANAMINE
3-PYRIDYLMETHYLAMINE
AKOS BBS-00003679
C-PYRIDIN-3-YL-METHYLAMINE
OMEGA-AMINO-B-PICOLINE
Picolamine
RARECHEM AL BW 0100
TIMTEC-BB SBB004351
-(Aminomethyl)pyridine
3-Pyridinemethaneamine
3-Pyridinemethylamine
3-Pyridinylmethanamine
-Aminomethyl
Pyridine, 3-(aminomethyl)-
3-(AMINOMETHYL)PYRIDINE, 99+%
3-(aminomehtyl)pyridine
(Pyridin-3-yl)methylamine | [EINECS(EC#)]
223-091-0 | [Molecular Formula]
C6H8N2 | [MDL Number]
MFCD00006412 | [Molecular Weight]
108.14 | [MOL File]
3731-52-0.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR COLOURLESS TO SLIGHLY YELLOW LIQUID | [Melting point ]
−21 °C(lit.)
| [Boiling point ]
73-74 °C1 mm Hg(lit.)
| [density ]
1.062 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.551(lit.)
| [Fp ]
213 °F
| [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
soluble in Chloroform, Ethyl Acetate, Methanol | [form ]
clear liquid | [pka]
8.34±0.29(Predicted) | [color ]
Colorless to Light yellow | [PH]
11-12 (100g/l, H2O, 20℃) | [Water Solubility ]
FREELY SOLUBLE | [Sensitive ]
Air Sensitive | [BRN ]
108056 | [CAS DataBase Reference]
3731-52-0(CAS DataBase Reference) | [NIST Chemistry Reference]
Picolamine(3731-52-0) | [EPA Substance Registry System]
3731-52-0(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
C,Xi | [Risk Statements ]
R34:Causes burns.
R37:Irritating to the respiratory system.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S25:Avoid contact with eyes .
S36:Wear suitable protective clothing . | [RIDADR ]
UN 2735 8/PG 2
| [WGK Germany ]
3
| [Hazard Note ]
Irritant | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29333999 |
| Hazard Information | Back Directory | [Chemical Properties]
CLEAR COLOURLESS TO SLIGHLY YELLOW LIQUID | [Uses]
rubefacient | [Application]
3-(Aminomethyl)pyridine can be used to prepare metal complexes. A number of complexes of cobalt(II), nickel(II) and copper(II) thiocyanates, chlorides and bromides with 3-pyridine amine were prepared and the stereochemical configurations of these complexes were deduced using spectroscopy and magnetism, and the decomposition of the complexes was studied by thermogravimetry and differential thermal analysis[2]. | [Synthesis]
Synthesis of 3-(aminomethyl)pyridine by traceless C3-selective umpolung of 1-amidopyridin-1-ium salts?. A natural product inspired rapid access of 3-(aminomethyl)pyridine by one-pot reaction of 1-amidopyridin-1-ium salt with aminal followed by reductive cleavage of the N–N bond is developed. This C3-selective formal C–H activation of pyridine features a traceless umpolung of the 1-amidopyridin-1-ium salt toward a Mannich type C–C bond formation of the in situ generated 1-amido-2-dialkylamino-1,2-dihydropyridine intermediate[1]. | [References]
[1] TANG P, XIAO D, WANG B. Synthesis of 3-(aminomethyl)pyridine by traceless C3-selective umpolung of 1-amidopyridin-1-ium salts?[J]. Chemical Communications, 2017. DOI:10.1039/C6CC09582H.
[2] J. R. ALLAN M. J P A D Paton. The preparation, characterisation and thermal analysis studies on complexes of cobalt(II), nickel(II), and copper(II) with 3-picolylamine[J]. Journal of Thermal Analysis and Calorimetry, 1985. DOI:10.1007/BF01913603.
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