| Identification | More | [Name]
2-Chloro-5-chloromethylpyridine | [CAS]
70258-18-3 | [Synonyms]
2,5-DICHLORO-4-METHYL-PYRIDINE
2-CHLORO-5-CHLOROMETHYLPYRIDINE
AKOS MSC-0759
AURORA KA-6694
TIMTEC-BB SBB003948
2-CHLORO-5-CHLOROMETHYLPYRIDINE 90%
2-Chloro-5-ChloroMethylPyridine(Ccmp)98%
2-Chloro-5-Chloro Methyl Pyridine (Ccmp) 98%
Pyridine, 2-chloro-5-(chloromethyl)-(9CI)
2-Chloro-5-chloromethylpyridine, tech., 90%
imidacloprid impurity
2-CHLORO-5-(CHLOROMETHYL)PYRIDINE[FOR IMIDACLOPRID]
2-CHLORO-5-CHLOROMETHYLPYRIDINE 2-CHLORO-5-CHLOROMETHYLPYRIDINE
2-CHLORO-5-CHLOROMETHYLPYRIDINE, 90%, TECH. | [EINECS(EC#)]
615-091-8 | [Molecular Formula]
C6H5Cl2N | [MDL Number]
MFCD00125366 | [Molecular Weight]
162.02 | [MOL File]
70258-18-3.mol |
| Chemical Properties | Back Directory | [Appearance]
beige moist crystals | [Melting point ]
37-42 °C(lit.)
| [Boiling point ]
267.08°C (rough estimate) | [density ]
1.4411 (rough estimate) | [refractive index ]
1.6000 (estimate) | [Fp ]
>230 °F
| [storage temp. ]
Refrigerator | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Moist Crystals | [pka]
-0.75±0.10(Predicted) | [color ]
Beige | [Water Solubility ]
Insoluble in water. | [BRN ]
1635690 | [InChI]
InChI=1S/C6H5Cl2N/c7-3-5-1-2-6(8)9-4-5/h1-2,4H,3H2 | [InChIKey]
SKCNYHLTRZIINA-UHFFFAOYSA-N | [SMILES]
C1(Cl)=NC=C(CCl)C=C1 | [CAS DataBase Reference]
70258-18-3(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
C,Xi,F | [Risk Statements ]
R22:Harmful if swallowed.
R34:Causes burns.
R36:Irritating to the eyes.
R10:Flammable. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S25:Avoid contact with eyes .
S36:Wear suitable protective clothing .
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
UN 3261 8/PG 2
| [WGK Germany ]
3
| [Hazard Note ]
Corrosive/Harmful | [HazardClass ]
8 | [HazardClass ]
LACHRYMATOR, CORROSIVE | [PackingGroup ]
II | [HS Code ]
29333999 |
| Questions And Answer | Back Directory | [Description]
2-Chloro-5-chloromethylpyridine is used for the synthesis of various pharmaceutical compounds. It can also be used for the synthesis of new neonicotinoid compounds1, having insecticidal activity. It is the raw material of pesticide products such as imidacloprid, acetamiprid as well as bactericide and herbicide2,3.
| [Structure]
2-Chloro-5-(chloromethyl)pyridine, C6H5Cl2N, is almost planar, with an r.m.s. deviation of 0.0146?? for all atoms except for the 5-choloromethyl Cl atom. The offset Cl atom lies above this plane with a Cl—C—C angle of 111.11?(17)°. In the crystal, mol-ecules are connected via inter-molecular C—H?N hydrogen bonds, forming dimers. The crystals were obtained by dissolving 2-Chloro-5-(chloromethyl)pyridine (0.2 g, 1.2 mmol) in ethanol (25 ml) and evaporating the solvent slowly at room temperature for about 5 d[1].
 | [Sources]
- https://www.alfa.com/en/catalog/L19284/
- https://www.trc-canada.com/product-detail/?C364715
- www.szqhbio.com/wap_news_detailen/id/1.htm
|
| Hazard Information | Back Directory | [Chemical Properties]
beige moist crystals | [Uses]
2-Chloro-5-(chloromethyl)pyridine is used for the synthesis of various pharmaceutical compounds. It can also be used for the synthesis of new neonicotinoid compounds. | [References]
[1] Zhi-Qiang Feng. “2-Chloro-5-(chloro-meth-yl)pyridine.” Acta crystallographica. Section E, Structure reports online 67 Pt 2 (2011): o366.
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