| Identification | More | [Name]
NICOTINIC ACID HYDRAZIDE | [CAS]
553-53-7 | [Synonyms]
AKOS BBS-00004102
LABOTEST-BB LT01593663
NICOTINIC ACID HYDRAZIDE
NICOTINIC ACID HYDRAZINE
NICOTINIC HYDRAZIDE
NICOTINOHYDRAZIDE
PYRIDINE-3-CARBOHYDRAZIDE
PYRIDINE-3-CARBOXYLIC ACID HYDRAZIDE
(3-pyridylcarbonyl)hydrazine
3-Pyridinecarboxylic acid, hydrazide
3-Pyridinecarboxylic hydrazide
3-pyridinecarboxylicacid,hydrazide
3-Pyridoyl Hydrazine
3-pyridoylhydrazine
3-Pyridylcarbonylhydrazine
Hydrazine, nicotinoyl-
Niazid
Nicotinoyl hydrazide
nicotinoyl-hydrazin
Nicotinylhydrazide | [EINECS(EC#)]
209-041-0 | [Molecular Formula]
C6H7N3O | [MDL Number]
MFCD00006383 | [Molecular Weight]
137.14 | [MOL File]
553-53-7.mol |
| Chemical Properties | Back Directory | [Appearance]
WHITE TO OFF-WHITE FINE NEEDLE-LIKE CRYST. POWDER | [Melting point ]
159-161 °C(lit.)
| [Boiling point ]
251.97°C (rough estimate) | [density ]
1.2620 (rough estimate) | [refractive index ]
1.6910 (estimate) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
H2O: soluble50mg/mL | [form ]
Fine Needle-Like Crystalline Powder | [pka]
11.43±0.10(Predicted) | [color ]
White to off-white | [Water Solubility ]
Soluble in alcohol, water. | [Detection Methods]
HPLC,NMR | [BRN ]
119299 | [InChIKey]
KFUSANSHCADHNJ-UHFFFAOYSA-N | [CAS DataBase Reference]
553-53-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
UN2811 | [WGK Germany ]
3
| [RTECS ]
QT1750000
| [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29280000 | [Toxicity]
LD50 intravenous in mouse: 180mg/kg |
| Hazard Information | Back Directory | [Chemical Properties]
WHITE TO OFF-WHITE FINE NEEDLE-LIKE CRYST. POWDER | [Uses]
Nicotinic hydrazide was used in hydrazone library formation. It was used to study the oxidation of isonicotinic acid hydrazide (isoniazid) by horseradish peroxidase. | [Uses]
An Impurity of Isoniazid (I821450), potent antitubercular agent against M. tuberculosis.
| [Biochem/physiol Actions]
Nicotinic hydrazide is an inhibitor of peroxidase enzyme. It forms solid metal complexes having strong biological activity. | [Purification Methods]
Crystallise it from aqueous EtOH or *benzene. [Beilstein 22 III/IV 439, 22/2 V 121.] |
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