| Identification | More | [Name]
2-Chloropyridine | [CAS]
109-09-1 | [Synonyms]
2-CHLOROPYRIDINE
2CLPY
ALPHA-CHLOROPYRIDINE
2-chloro-pyridin
o-Chloropyridine
α-chloropyridine
Pyridine, 2-chloro-
2-Chloropyridine ,99%
2-Pyridinyl chloride | [EINECS(EC#)]
203-646-3 | [Molecular Formula]
C5H4ClN | [MDL Number]
MFCD00006228 | [Molecular Weight]
113.54 | [MOL File]
109-09-1.mol |
| Chemical Properties | Back Directory | [Appearance]
Clear colourless to light yellow liquid | [Melting point ]
-46 °C | [Boiling point ]
166 °C/714 mmHg (lit.) | [density ]
1.209 | [vapor pressure ]
1.7 mm Hg ( 20 °C)
| [refractive index ]
n20/D 1.532(lit.)
| [Fp ]
149 °F
| [storage temp. ]
Refrigerator | [solubility ]
27g/l | [form ]
Liquid | [pka]
0.49(at 25℃) | [color ]
Clear colorless to light yellow | [PH]
6-7 (27g/l, H2O, 20℃) | [Water Solubility ]
27 g/L (20 ºC) | [Detection Methods]
HPLC,NMR | [BRN ]
105788 | [CAS DataBase Reference]
109-09-1(CAS DataBase Reference) | [NIST Chemistry Reference]
Pyridine, 2-chloro-(109-09-1) | [EPA Substance Registry System]
2-Chloropyridine (109-09-1) |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S27:Take off immediately all contaminated clothing . | [RIDADR ]
UN 2822 6.1/PG 2
| [WGK Germany ]
3
| [RTECS ]
US5950000
| [Hazard Note ]
Toxic | [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
II | [HS Code ]
29333999 | [Safety Profile]
Poison by ingestion,
inhalation, skin contact, and intraperitoneal
routes. Combustible when exposed to heat
or flame. Can react with oxidizing materials.
When heated to decomposition it emits very
toxic fumes of Cl-, NOx, and phosgene. | [Hazardous Substances Data]
109-09-1(Hazardous Substances Data) |
| Hazard Information | Back Directory | [General Description]
A colorless oily liquid. Toxic by ingestion and/or skin absorption. Used to make other chemicals. | [Air & Water Reactions]
Slightly soluble in water and denser than water. | [Hazard]
Toxic by ingestion. | [Fire Hazard]
Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form. | [Chemical Properties]
Clear colourless to light yellow liquid | [Uses]
2- Chloropyridine is used as an intermediate chemical in the production of various pyrithione, for use in cosmetics, personal care products and pharmaceutical products. | [Uses]
2-Chloropyridine (2-CPY) has been identified as a trace organic chemical in process streams, wastewater and even drinking water. Furthermore, it appears to be formed as a secondary pollutant during t
he decomposition of specific insecticides. | [Definition]
ChEBI: 2-chloropyridine is a monochloropyridine. | [Synthesis Reference(s)]
Synthetic Communications, 19, p. 897, 1989 DOI: 10.1080/00397918908051009
Synthesis, p. 337, 1990 | [Purification Methods]
Dry 2-chloropyridine with NaOH for several days, then distil it from CaO under reduced pressure. [Beilstein 20/5 V 402.] |
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