Identification | More | [Name]
5-Amino-2-chloropyridine | [CAS]
5350-93-6 | [Synonyms]
2-CHLORO-5-AMINOPYRIDINE 3-AMINO-6-CHLOROPYRIDINE 3-PYRIDINAMINE, 6-CHLORO- 5-AMINO-2-CHLOROPYRIDINE 6-CHLOROPYRIDIN-3-AMINE 6-CHLORO-PYRIDIN-3-YLAMINE TIMTEC-BB SBB004234 AMINO CHLOROPYRIDINE 6-chloro-3-pyridinamine 3-Pyridinamine,6-chloro-(9CI) 5-BROMO-2-METHOXYPHENOL 5-Amino-2-chloropyridine ,98% 2-Chloro-5-pyridinamine 2-Chloropyridine-5-amine | [EINECS(EC#)]
226-322-3 | [Molecular Formula]
C5H5ClN2 | [MDL Number]
MFCD00006243 | [Molecular Weight]
128.56 | [MOL File]
5350-93-6.mol |
Chemical Properties | Back Directory | [Appearance]
Light yellow to brown crystalline powder | [Melting point ]
81-83 °C(lit.)
| [Boiling point ]
205.39°C (rough estimate) | [density ]
1.2417 (rough estimate) | [refractive index ]
1.5110 (estimate) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [form ]
powder to crystal | [pka]
1.94±0.10(Predicted) | [color ]
White to Brown | [Detection Methods]
HPLC,NMR | [BRN ]
108891 | [InChIKey]
QAJYCQZQLVENRZ-UHFFFAOYSA-N | [CAS DataBase Reference]
5350-93-6(CAS DataBase Reference) |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing . S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29333990 |
Hazard Information | Back Directory | [Chemical Properties]
Light yellow to brown crystalline powder | [Uses]
5-Amino-2-chloropyridine was used in the synthesis of [2H5]2-amino-l-methyl-6-phenylimidazo[4,5-b]pyridine. It was used in identification and evaluation of molecularly imprinted polymers for the selective removal of potentially genotoxic aminopyridine impurities from pharmaceuticals. | [Definition]
ChEBI: 3-Amino-6-chloropyridine is an aminopyridine. | [General Description]
5-Amino-2-chloropyridine undergoes Suzuki-Miyaura coupling with sterically hindered 2,6-dimethylphenylboronic acid. It undergoes facile temperature dependent displacement of chloride by bromide via Sandmeyer reaction to yield 2,5-dibromopyridine. |
|
|