| Identification | More | [Name]
6-Chloro-2-picoline | [CAS]
18368-63-3 | [Synonyms]
2-CHLORO-6-METHYLPYRIDINE
2-CHLORO-6-PICOLINE
6-CHLORO-2-METHYLPYRIDINE
6-CHLORO-2-PICOLINE
2-Picoline, 6-chloro-
Pyridine, 2-chloro-6-methyl-
2-Chioro-6-Methylpyridine
2-CHLORO-6-METHYLPYRIDINE 98%
6-CHLORO-ALPHA-PICOLINE
2-CHLORO-6-PICOLINE 2-CHLORO-6-METHYLPYRIDINE
2-CHLORO-6-METHYLPYRIDINE (2-CHLORO-6-PICOLINE)
6-Methyl-2-chloropyridine
2-Chloro-6-methylpyridine ,99%
2-Methyl-6-chloropyridine | [EINECS(EC#)]
242-241-6 | [Molecular Formula]
C6H6ClN | [MDL Number]
MFCD00006245 | [Molecular Weight]
127.57 | [MOL File]
18368-63-3.mol |
| Chemical Properties | Back Directory | [Appearance]
Light yellow liquid | [Boiling point ]
64-68 °C10 mm Hg(lit.)
| [density ]
1.167 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.527(lit.)
| [Fp ]
165 °F
| [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
Liquid | [pka]
1.10±0.10(Predicted) | [color ]
Clear colorless to light yellow | [Specific Gravity]
1.167 | [Detection Methods]
GC,NMR | [BRN ]
107187 | [InChI]
InChI=1S/C6H6ClN/c1-5-3-2-4-6(7)8-5/h2-4H,1H3 | [InChIKey]
GXZDYRYYNXYPMQ-UHFFFAOYSA-N | [SMILES]
C1(Cl)=NC(C)=CC=C1 | [CAS DataBase Reference]
18368-63-3(CAS DataBase Reference) | [NIST Chemistry Reference]
2-Cl-6-(CH3)-pyridine(18368-63-3) | [EPA Substance Registry System]
18368-63-3(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
UN2810 | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29333990 |
| Hazard Information | Back Directory | [Description]
2-Chloro-6-methylpyridine (2C6MP,18368-63-3) is a strong inhibitor of methane monooxygenase, a key enzyme in the aerobic oxidation of methane (CH4). It belongs to the pesticide nitropyridine group of compounds. Studies have shown that 2C6MP has the least effect on CH4 oxidation at concentrations of 0.1 mM and 1 mM, but at a concentration of 10 mM, 2C6MP inhibits CH4 oxidation for >20 months. Low concentrations of 2C6MP did not inhibit Methylophilaceae, while high concentrations of 2C6MP inhibited Methylophilaceae by only 7.8 ± 1.1%[1].
| [Chemical Properties]
Light yellow liquid | [Uses]
2-Chloro-6-methylpyridine(18368-63-3) has been used for experimental FTIR and FT-Raman spectroscopic analyses, as well as for conformational studies.
| [References]
[1] E. O’LOUGHLIN. Inhibition of Microbial Methane Oxidation by 2-Chloro-6-Methylpyridine[J]. bioRxiv?: the preprint server for biology, 2022. DOI:10.1101/2022.10.13.512149. |
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