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ChemicalBook >> CAS DataBase List >> Selonsertib

Selonsertib

Selonsertib price.
  • $32 - $1609
  • Product name: Selonsertib
  • CAS: 1448428-04-3
  • MF: C24H24FN7O
  • MW: 445.49
  • EINECS:
  • MDL Number:MFCD29920355
  • Synonyms:Selonsertib;5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]benzamide;Selonsertib GS-4997;GS-4497;GS-4997;ASK-1;GS4997 SELONSERTIB;5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide;Benzamide, 5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]-
32 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Ark Pharm
  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1231-M005
  • Product descriptionSelonsertib(freebase) ≥95%
  • Packaging5mg
  • Price$205
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1231-M010
  • Product descriptionSelonsertib(freebase) ≥95%
  • Packaging10mg
  • Price$313
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1231-M100
  • Product descriptionSelonsertib(freebase) ≥95%
  • Packaging100mg
  • Price$1609
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN1231
  • Product descriptionSelonsertib
  • Packaging100mg
  • Price$1510
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004753
  • Product description5-(4-CYCLOPROPYL-1H-IMIDAZOL-1-YL)-2-FLUORO-4-METHYL-N-[6-[4-(1-METHYLETHYL)-4H-1,2,4-TRIAZOL-3-YL]-2-PYRIDINYL]-BENZAMIDE 95.00%
  • Packaging5MG
  • Price$497.89
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7812
  • Product descriptionSelonsertib(GS-4997)
  • Packaging5mg
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7812
  • Product descriptionSelonsertib(GS-4997)
  • Packaging25mg
  • Price$208
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7812
  • Product descriptionSelonsertib(GS-4997)
  • Packaging100mg
  • Price$474
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000132047
  • Product descriptionSelonsertib 97%
  • Packaging1mg
  • Price$63
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000132047
  • Product descriptionSelonsertib 97%
  • Packaging5mg
  • Price$86
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000132047
  • Product descriptionSelonsertib 97%
  • Packaging10mg
  • Price$156
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000132047
  • Product descriptionSelonsertib 97%
  • Packaging50mg
  • Price$469
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000132047
  • Product descriptionSelonsertib 97%
  • Packaging100mg
  • Price$688
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000132047
  • Product descriptionSelonsertib 97%
  • Packaging250mg
  • Price$1156
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2956
  • Product descriptionSelonsertib-GS4997 99%
  • Packaging10mg
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC157241
  • Product descriptionSelonsertib
  • Packaging250mg
  • Price$500
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences SYN-1231-M005 Selonsertib(freebase) ≥95% 5mg $205 2021-12-16 Buy
Adipogen Life Sciences SYN-1231-M010 Selonsertib(freebase) ≥95% 10mg $313 2021-12-16 Buy
Adipogen Life Sciences SYN-1231-M100 Selonsertib(freebase) ≥95% 100mg $1609 2021-12-16 Buy
AK Scientific SYN1231 Selonsertib 100mg $1510 2021-12-16 Buy
American Custom Chemicals Corporation INB0004753 5-(4-CYCLOPROPYL-1H-IMIDAZOL-1-YL)-2-FLUORO-4-METHYL-N-[6-[4-(1-METHYLETHYL)-4H-1,2,4-TRIAZOL-3-YL]-2-PYRIDINYL]-BENZAMIDE 95.00% 5MG $497.89 2021-12-16 Buy
ApexBio Technology B7812 Selonsertib(GS-4997) 5mg $68 2021-12-16 Buy
ApexBio Technology B7812 Selonsertib(GS-4997) 25mg $208 2021-12-16 Buy
ApexBio Technology B7812 Selonsertib(GS-4997) 100mg $474 2021-12-16 Buy
Ark Pharm P000132047 Selonsertib 97% 1mg $63 2021-12-16 Buy
Ark Pharm P000132047 Selonsertib 97% 5mg $86 2021-12-16 Buy
Ark Pharm P000132047 Selonsertib 97% 10mg $156 2021-12-16 Buy
Ark Pharm P000132047 Selonsertib 97% 50mg $469 2021-12-16 Buy
Ark Pharm P000132047 Selonsertib 97% 100mg $688 2021-12-16 Buy
Ark Pharm P000132047 Selonsertib 97% 250mg $1156 2021-12-16 Buy
Axon Medchem Axon2956 Selonsertib-GS4997 99% 10mg $99 2021-12-16 Buy
Biosynth Carbosynth FC157241 Selonsertib 250mg $500 2021-12-16 Buy

Properties

Melting point :>180°C (dec.)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
pka :11.21±0.70(Predicted)
form :solid
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
CAS DataBase Reference :1448428-04-3

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P314 Get medical advice/attention if you feel unwell.
P501 Dispose of contents/container to..…

Description

Selonsertib (1448428-04-3) is a potent Apoptosis signal-regulating kinase 1 (ASK1) inhibitor (pIC50 = 8.3)1 found to improve metabolic parameters in nonalcoholic steatohepatitis, reduce hepatic steatosis, inflammation, and fibrosis2-4. Selonsertib suppressed the efflux function of multidrug resistance (MDR) transporters ABCB1 and ABCG2.5

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