Enasidenib
|
- $75 - $1400
- Product name: Enasidenib
- CAS: 1446502-11-9
- MF: C19H17F6N7O
- MW: 473.38
- EINECS:
- MDL Number:MFCD29472245
- Synonyms:Enasidenib(AG-221);AG-221 (Enasidenib);AG-211;2-Methyl-1-(4-(6-(trifluoromethyl)pyridin-2-yl)-6-(2-(trifluoromethyl)pyridin-4-ylamino)-1,3,5-triazin-2-ylamino)propan-2-ol;Enasidenib;AG-221;2-Propanol, 2-methyl-1-[[4-[6-(trifluoromethyl)-2-pyridinyl]-6-[[2-(trifluoromethyl)-4-pyridinyl]amino]-1,3,5-triazin-2-yl]amino]-;Enasidenib Mesylate
25 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- TRC
- Usbiological
Package
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 1g
- ManufacturerAK Scientific
- Product number1996EB
- Product descriptionEnasidenib
- Packaging10mg
- Price$212
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1996EB
- Product descriptionEnasidenib
- Packaging50mg
- Price$509
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004694
- Product descriptionENASIDENIB 95.00%
- Packaging5MG
- Price$498.27
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7804
- Product descriptionAG-221(Enasidenib)
- Packaging5mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7804
- Product descriptionAG-221(Enasidenib)
- Packaging25mg
- Price$278
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2745
- Product descriptionAG-221-Enasidenib 99%
- Packaging10mg
- Price$104.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546243
- Product descriptionEnasidenib >98%
- Packaging5mg
- Price$163.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546243
- Product descriptionEnasidenib >98%
- Packaging25mg
- Price$430.1
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA145490
- Product descriptionAG 221
- Packaging10mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA145490
- Product descriptionAG 221
- Packaging50mg
- Price$340
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21277
- Product descriptionEnasidenib ≥98%
- Packaging5mg
- Price$97
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21277
- Product descriptionEnasidenib ≥98%
- Packaging10mg
- Price$184
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21277
- Product descriptionEnasidenib ≥98%
- Packaging25mg
- Price$433
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21277
- Product descriptionEnasidenib ≥98%
- Packaging100mg
- Price$1151
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5017
- Product descriptionEnasidenib 99.93%
- Packaging5mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5017
- Product descriptionEnasidenib 99.93%
- Packaging10mg
- Price$120
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1996EB | Enasidenib | 10mg | $212 | 2021-12-16 | Buy |
| AK Scientific | 1996EB | Enasidenib | 50mg | $509 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0004694 | ENASIDENIB 95.00% | 5MG | $498.27 | 2021-12-16 | Buy |
| ApexBio Technology | B7804 | AG-221(Enasidenib) | 5mg | $75 | 2021-12-16 | Buy |
| ApexBio Technology | B7804 | AG-221(Enasidenib) | 25mg | $278 | 2021-12-16 | Buy |
| Axon Medchem | Axon2745 | AG-221-Enasidenib 99% | 10mg | $104.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546243 | Enasidenib >98% | 5mg | $163.2 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546243 | Enasidenib >98% | 25mg | $430.1 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA145490 | AG 221 | 10mg | $120 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA145490 | AG 221 | 50mg | $340 | 2021-12-16 | Buy |
| Cayman Chemical | 21277 | Enasidenib ≥98% | 5mg | $97 | 2024-03-01 | Buy |
| Cayman Chemical | 21277 | Enasidenib ≥98% | 10mg | $184 | 2024-03-01 | Buy |
| Cayman Chemical | 21277 | Enasidenib ≥98% | 25mg | $433 | 2024-03-01 | Buy |
| Cayman Chemical | 21277 | Enasidenib ≥98% | 100mg | $1151 | 2024-03-01 | Buy |
| ChemScene | CS-5017 | Enasidenib 99.93% | 5mg | $84 | 2021-12-16 | Buy |
| ChemScene | CS-5017 | Enasidenib 99.93% | 10mg | $120 | 2021-12-16 | Buy |
Properties
Melting point :168-170°C
Boiling point :581.0±60.0 °C(Predicted)
Density :1.477±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 25 mg/ml)
form :solid
pka :14.70±0.29(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Boiling point :581.0±60.0 °C(Predicted)
Density :1.477±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 25 mg/ml)
form :solid
pka :14.70±0.29(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
Enasidenib (1446502-11-9) is a potent (IC50’s = 100 nM IDH2R140Q homodimer, 30 nM IDH2R140Q/WT heterodimer and 10 nM IDH2R172K/WT heterodimer) and selective inhibitor of mutant isocitrate dehydrogenase 2 (IDH2).1? It suppressed the production of the oncometabolite (R)-2-Hydroxyglutarate (a competitive inhibitor of αKG-dependent dioxygenases which leads to epigenetic dysregulation) and induced cellular differentiation in primary human IDH2 mutation-positive acute myeloid leukemia cells.1,2? Recently approved for clinical use by the FDA.More related product prices
1204669-58-8 RVX-208 1218942-37-0 BLU 9931 AZD6738 Selonsertib Ponatinib ABBV-075 RG120 1268524-70-4 N2'-deacetyl-N2'-(3-Mercapto-1-oxopropyl)-Maytansine EPZ-6438 SH-4-54Related product price
- 1204669-58-8
$30-2000 - RVX-208
$44-1423 - 1218942-37-0
$32-1545
Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
HANGZHOU CLAP TECHNOLOGY CO.,LTD
ANHUI WITOP BIOTECH CO., LTD
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
Nanjing Doge Biomedical Technology Co., Ltd
