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ChemicalBook >> CAS DataBase List >> Epacadostat (INCB024360)

Epacadostat (INCB024360)

Epacadostat (INCB024360) price.
  • $30 - $2000
  • Product name: Epacadostat (INCB024360)
  • CAS: 1204669-58-8
  • MF: C11H13BrFN7O4S
  • MW: 438.23
  • EINECS:
  • MDL Number:MFCD29075639
  • Synonyms:(Z)-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-((2-(sulfamoylamino)ethyl)amino)-1,2,5-oxadiazole-3-carboximidamide;Epacadostat (INCB24360, INCB024360);N-(3-Bromo-4-fluoro-phenyl)-N'-hydroxy-4-[2-(sulfamoylamino)ethylamino]-1,2,5-oxadiazole-3-carboxamidine;INCN024360;(Z)-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-[2-(sulfamoylamino)ethylamino]-1,2,5-oxadiazole-3-carboxamidine;Epacadostat(INCN024360);INCB-24360(INCB-024360);Epacadostat(INCB024360)
29 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 2x25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • 2g
  • ManufacturerAK Scientific
  • Product number3196EM
  • Product descriptionEpacadostat
  • Packaging10mg
  • Price$178
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3196EM
  • Product descriptionEpacadostat
  • Packaging50mg
  • Price$498
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA205097
  • Product description(Z)-N-(3-Bromo-4-fluorophenyl)-N'-hydroxy-4-[2-(sulfamoylamino)ethylamino]-1,2,5-oxadiazole-3-carboxamidine 98+%
  • Packaging5mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA205097
  • Product description(Z)-N-(3-Bromo-4-fluorophenyl)-N'-hydroxy-4-[2-(sulfamoylamino)ethylamino]-1,2,5-oxadiazole-3-carboxamidine 98+%
  • Packaging10mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA205097
  • Product description(Z)-N-(3-Bromo-4-fluorophenyl)-N'-hydroxy-4-[2-(sulfamoylamino)ethylamino]-1,2,5-oxadiazole-3-carboxamidine 98+%
  • Packaging50mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA205097
  • Product description(Z)-N-(3-Bromo-4-fluorophenyl)-N'-hydroxy-4-[2-(sulfamoylamino)ethylamino]-1,2,5-oxadiazole-3-carboxamidine 98+%
  • Packaging1g
  • Price$418
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6036
  • Product descriptionINCB-024360
  • Packaging25mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1733
  • Product descriptionINCB024360-Epacadostat 98%
  • Packaging5mg
  • Price$115.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1733
  • Product descriptionINCB024360-Epacadostat 98%
  • Packaging2x25mg
  • Price$616
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA103715
  • Product descriptionEpacadostat
  • Packaging10mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA103715
  • Product descriptionEpacadostat
  • Packaging50mg
  • Price$332.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19875
  • Product descriptionINCB024360 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19875
  • Product descriptionINCB024360 ≥98%
  • Packaging5mg
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19875
  • Product descriptionINCB024360 ≥98%
  • Packaging10mg
  • Price$214
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19875
  • Product descriptionINCB024360 ≥98%
  • Packaging25mg
  • Price$494
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1496
  • Product descriptionEpacadostat 99.66%
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3196EM Epacadostat 10mg $178 2021-12-16 Buy
AK Scientific 3196EM Epacadostat 50mg $498 2021-12-16 Buy
Ambeed A205097 (Z)-N-(3-Bromo-4-fluorophenyl)-N'-hydroxy-4-[2-(sulfamoylamino)ethylamino]-1,2,5-oxadiazole-3-carboxamidine 98+% 5mg $30 2021-12-16 Buy
Ambeed A205097 (Z)-N-(3-Bromo-4-fluorophenyl)-N'-hydroxy-4-[2-(sulfamoylamino)ethylamino]-1,2,5-oxadiazole-3-carboxamidine 98+% 10mg $39 2021-12-16 Buy
Ambeed A205097 (Z)-N-(3-Bromo-4-fluorophenyl)-N'-hydroxy-4-[2-(sulfamoylamino)ethylamino]-1,2,5-oxadiazole-3-carboxamidine 98+% 50mg $66 2021-12-16 Buy
Ambeed A205097 (Z)-N-(3-Bromo-4-fluorophenyl)-N'-hydroxy-4-[2-(sulfamoylamino)ethylamino]-1,2,5-oxadiazole-3-carboxamidine 98+% 1g $418 2021-12-16 Buy
ApexBio Technology B6036 INCB-024360 25mg $180 2021-12-16 Buy
Axon Medchem Axon1733 INCB024360-Epacadostat 98% 5mg $115.5 2021-12-16 Buy
Axon Medchem Axon1733 INCB024360-Epacadostat 98% 2x25mg $616 2021-12-16 Buy
Biosynth Carbosynth FA103715 Epacadostat 10mg $95 2021-12-16 Buy
Biosynth Carbosynth FA103715 Epacadostat 50mg $332.5 2021-12-16 Buy
Cayman Chemical 19875 INCB024360 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 19875 INCB024360 ≥98% 5mg $139 2024-03-01 Buy
Cayman Chemical 19875 INCB024360 ≥98% 10mg $214 2024-03-01 Buy
Cayman Chemical 19875 INCB024360 ≥98% 25mg $494 2024-03-01 Buy
ChemScene CS-1496 Epacadostat 99.66% 5mg $50 2021-12-16 Buy

Properties

Melting point :159 - 161°C
Boiling point :700.9±70.0 °C(Predicted)
Density :2.01±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
form :solid
pka :7.65±0.69(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P322 Specific measures (see …on this label).
P330 Rinse mouth.
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/container to..…

Description

INCB024360 is an inhibitor of indoleamine 2,3-dioxygenase-1 (IDO1) with an IC50 value of 7.1 nM in HeLa cells that demonstrates little activity against the related enzymes IDO2 or tryptophan 2,3-dioxygenase (TDO). It has been shown to promote T- and natural killer-cell growth, to increase IFN-γ production, and to reduce conversion to regulatory T (Treg)-like cells in a coculture system of human allogeneic lymphocytes with either dendritic cells or tumor cells. INCB024360 can also inhibit tumor growth in tumor-bearing mice in a lymphocyte-dependent manner.

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