ChemicalBook >?? ???? >???????
???????
|
|
??????? ??
- ???
- 186-188°C
- ?? ??
- Inert atmosphere,Room Temperature
- ???
- DMSO: ~11mg/mL( 60 °C)
- ??? ??
- ??
- ??? ??
- ??? ??
- ??
- ???
- ?? ??(λmax)
- 248nm(MeOH)(lit.)
- Merck
- 14,6438
- CAS ??????
- 82752-99-6(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ????? | 22-24/25 | ||
|---|---|---|---|
| ????(UN No.) | UN1230 - class 3 - PG 2 - Methanol, solution | ||
| WGK ?? | 3 | ||
| RTECS ?? | XZ5483009 | ||
| HS ?? | 2933595960 |
| ????(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ?? ?: | Warning | |||||||||||||||||||||||||||||||||||
| ??·?? ??: |
|
|||||||||||||||||||||||||||||||||||
| ??????: |
|
??????? C??? ??, ??, ??
??
Nefazodone, a second generation trazodone type antidepressant, was launched in Canada. Nefazodone acts as both a potent 5-HT2 receptor antagonist and as a serotonin (5-HT) reuptake inhibitor. This combination effect appears to enhance 5-HTIA-mediated neurotransmission. Distinct from the first generation agents such as tricyclic antidepressants, nefazodone has very selective serotonergic effects with negligible affinity for cholinergic and histamine receptors, and low affinity for a1 -adrenergic receptors. Therefore, it has a superior toxicity profile that does not produce agitation, insomnia, and lacks cardiac side effects.??? ??
White Solid??
A selective serotonin 5-HT2 receptor antagonist. A novel antidepressant that shows no cardiac toxicity or anticholinergic activity common with tricyclic antidepressants.?? ??
Nefazodone, formerly sold under the brand names Serzone, Dutonin, and Nefadar, is an antidepressant that has been discontinued due to the incidence of severe liver damage. This certified Snap-N-Spike; solution is suitable for use as a starting material in calibrators and controls for numerous GC/MS or LC/MS applications in forensic analysis, clinical toxicology and urine drug testing.???? ??
Serotonin 5-HT 2A receptor antagonist (K i = 5.8 nM) and inhibitor of serotonin and noradrenalin uptake (IC 50 values are 290 and 300 nM respectively). Displays no activity at 5-HT 1B and 5-HT 1D receptors. Active in models predictive of antidepressant potential.??????? ?? ?? ? ???
???
?? ??
??????? ?? ??
???( 222)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21631 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29865 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39894 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49732 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 |
1022@dideu.com | China | 3882 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32159 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 |
sales@afinechem.com | China | 15352 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 |
dominicguo@gk-bio.com | CHINA | 9414 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | China | 52849 | 58 |
??????? ?? ??:
????? ???? 1-(4-??????)-3,3-????-1-(1H-1,2,4-????-1-?)-2- ??? ????
Naphazoline hydrochloride
Topotecan hydrochloride
Nefazodone Related Compound A,Nefazodone Related Compound A
Nefazodone Related Compound B,Nefazodone Related Compound B
NEFAZODONE,Nefazodone base,Nefazodone (base and/or unspecified salts),NEFAZODONE,Nefazodone base,Nefazodone (base and/or unspecified salts)
1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride
HYDROXY NEFAZODONE HCL,HYDROXY NEFAZODONE HCL
Nefazodone hydrochloride
NEFAZODONE , TRAZODONE,NEFAZODONE , TRAZODONE
5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazole-3-one (intermediate of nefazodone hcl)
HYDROXY NEFAZODONE-D5 HCL,HYDROXY NEFAZODONE-D5 HCL