Methyljodid
|
|
Methyljodid Eigenschaften
- Schmelzpunkt:
- −64(lit.)
- Siedepunkt:
- 41-43 °C
- Dichte
- 2.28 g/mL at 25 °C(lit.)
- Dampfdichte
- 4.89 (vs air)
- Dampfdruck
- 24.09 psi ( 55 °C)
- Brechungsindex
- n
20/D 1.530
- Flammpunkt:
- −18 °F
- storage temp.
- 2-8°C
- L?slichkeit
- water: soluble14g/L at 20°C
- Aggregatzustand
- Liquid
- Wichte
- 2.280
- Farbe
- Clear
- Geruch (Odor)
- Sweet, ethereal odor
- PH
- 5.2 (H2O, 25℃)
- Explosionsgrenze
- 8.5-66% (v/v)
- Wasserl?slichkeit
- 14 g/L (20 ºC)
- Sensitive
- Light Sensitive
- Merck
- 14,6087
- BRN
- 969135
- Henry's Law Constant
- 5.06 at 21 °C (Gan and Yates, 1996)
- Expositionsgrenzwerte
- TLV-TWA 2 ppm (~11 mg/m3) (ACGIH), 5 ppm (MSHA and OSHA); carcinogenicity: Animal Limited Evidence (IARC), Suspected Human Carcinogen.
- Dielectric constant
- 7.0(20℃)
- Stabilit?t:
- Light Sensitive
- LogP
- 1.510
- CAS Datenbank
- 74-88-4(CAS DataBase Reference)
- IARC
- 3 (Vol. 41, Sup 7, 71) 1999
- NIST chemische Informationen
- Methyl iodide(74-88-4)
- EPA chemische Informationen
- Methyl iodide (74-88-4)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher | T,F,Xn | ||
---|---|---|---|
R-S?tze: | 21-23/25-37/38-40-11-39/23/24/25-23/24/25-38-20/22 | ||
S-S?tze: | 36/37-38-45-9-24-16-7-60-36/37/39-33-23-20-4 | ||
RIDADR | UN 2644 6.1/PG 1 | ||
OEB | B | ||
OEL | TWA: 2 ppm (10 mg/m3) [skin] | ||
WGK Germany | 1 | ||
RTECS-Nr. | PA9450000 | ||
F | 8 | ||
TSCA | Yes | ||
HazardClass | 6.1 | ||
PackingGroup | I | ||
HS Code | 29033990 | ||
Giftige Stoffe Daten | 74-88-4(Hazardous Substances Data) | ||
Toxizit?t | LD50 orally in rats: 76 mg/kg; LD50 s.c. in mice: 0.78 mmoles/kg (IARC, 1986) | ||
IDLA | 100 ppm |
Bildanzeige (GHS) |
![]() ![]() ![]() ![]() |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alarmwort | Achtung | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gefahrenhinweise |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sicherheit |
|
Methyljodid Chemische Eigenschaften,Einsatz,Produktion Methoden
ERSCHEINUNGSBILD
FARBLOSE FLüSSIGKEIT MIT CHARAKTERISTISCHEM GERUCH. BRAUNF?RBUNG BEI KONTAKT MIT LICHT UND FEUCHTIGKEIT.PHYSIKALISCHE GEFAHREN
Die D?mpfe sind schwerer als Luft. Sie k?nnen sich in tiefer gelegenen Bereichen sammeln und den Luftsauerstoff verdr?ngen.CHEMISCHE GEFAHREN
Zersetzung beim Erhitzen über 270°C unter Bildung von Iodwasserstoff. Reagiert sehr heftig mit starken Oxidationsmitteln. Reagiert sehr heftig mit Sauerstoff bei 300°C unter Explosionsgefahr.ARBEITSPLATZGRENZWERTE
TLV: 2 ppm (als TWA); Hautresorption; (ACGIH 2005).MAK: Hautresorption Krebserzeugend Kategorie: 2 (DFG 2006).
AUFNAHMEWEGE
Aufnahme in den K?rper durch Inhalation der D?mpfe, durch Verschlucken und über die Haut.INHALATIONSGEFAHREN
Beim Verdampfen bei 20°C kann sehr schnell eine gesundheitssch?dliche Kontamination der Luft eintreten.WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION:Die Substanz reizt die Augen, die Haut und die Atemwege. M?glich sind Auswirkungen auf das Zentralnervensystem. Die Auswirkungen treten u.U. verz?gert ein. ?rztliche Beobachtung notwendig.
LECKAGE
Gefahrenbereich verlassen! Fachmann zu Rate ziehen! Ausgelaufene Flüssigkeit m?glichst in abdichtbaren Beh?ltern sammeln. Reste mit Sand oder inertem Absorptionsmittel aufnehmen und an einen sicheren Ort bringen. Chemikalienschutzanzug mit umgebungsluftunabh?ngigem Atemschutzger?t.R-S?tze Betriebsanweisung:
R21:Gesundheitssch?dlich bei Berührung mit der Haut.R23/25:Giftig beim Einatmen und Verschlucken.
R37/38:Reizt die Atmungsorgane und die Haut.
R40:Verdacht auf krebserzeugende Wirkung.
R11:Leichtentzündlich.
R39/23/24/25:Giftig: ernste Gefahr irreversiblen Schadens durch Einatmen, Berührung mit der Haut und durch Verschlucken.
R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
R38:Reizt die Haut.
R20/22:Gesundheitssch?dlich beim Einatmen und Verschlucken.
S-S?tze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.S38:Bei unzureichender Belüftung Atemschutzger?t anlegen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S9:Beh?lter an einem gut gelüfteten Ort aufbewahren.
S24:Berührung mit der Haut vermeiden.
S16:Von Zündquellen fernhalten - Nicht rauchen.
Aussehen Eigenschaften
CH3I. Farblose, etherisch riechende Flüssigkeit.Gefahren für Mensch und Umwelt
Gefährliche Reaktionen mit Alkali- und Erdalkalimetallen.Kann Krebs erzeugen. Gesundheitsschädlich bei Berührung mit der Haut. Giftig beim Einatmen und Verschlucken. Reizt die Atmungsorgane und die Haut. Irreversibler Schaden möglich.
Latenzzeit bis zum Wirkungseintritt. ZNS-Störungen, Kopfschmerzen, Erbrechen, Schwindel, Müdigkeit, Störung der Bewegungskoordination, Herz-Kreislaufstörungen. Toxische Wirkung auf Leber und Nieren.
Wassergefährdender Stoff (WGK 2).
Schutzma?nahmen und Verhaltensregeln
Unbedingt im Abzug arbeiten! Wässrige 10%ige Ammoniaklösung bereitstellen.Gummi-Schutzhandschuhe (nur als kurzzeitiger Spritzschutz).
Verhalten im Gefahrfall
Kleine Spritzer im Abzug verdampfen lassen oder direkt mit 10%iger Ammoniaklösung abspülen. Größere Mengen mit Absorptionsmaterial aufnehmen und der Entsorgung zuführen. Ggf. Labor räumen!Atemschutz: Umluftunabhängig.
Methyliodid brennt selbst nicht. Brandbekämpfung auf Umgebung abstimmen! Vorsicht, Gefahr der Inhalation bei Bränden!
Erste Hilfe
Nach Hautkontakt: Mit viel Wasser abwaschen, danach mit Polyethylenglycol 400 (bereithalten) abspülen.Nach Augenkontakt: Mit viel Wasser mindestens 15 Minuten bei geöffnetem Lidspalt spülen. Augenarzt!
Nach Einatmen: Frischluft. Arzt!
Nach Kleidungskontakt: Benetzte Kleidung sofort ausziehen.
Ersthelfer: siehe gesonderten Anschlag
Sachgerechte Entsorgung
Methyliodid wird im Abzug vorsichtig unter starkem Rühren in eine 10%ige Ammoniak-Lösung eingetropft. Die Salzlösung wird neutralisiert und kann in den Abfluß gegeben werden.Chemische Eigenschaften
light yellow to light pink liquidPhysikalische Eigenschaften
Clear, colorless liquid which may become yellow, red, or brown on exposure to light and moistureVerwenden
.Iodomethane is an approved pesticide used to control insects, plant parasitic nematodes, soil borne pathogens and weed seeds.Vorbereitung Methode
Methyl iodide has had very limited use as a chemical intermediate (methylations), and in microscopy because of its high refractive index, as imbedding materials for examining diatoms, and in tests for pyridine. It has been proposed as a fire extinguisher and insecticidal fumigant. It is a product of natural biological processes. Methyl iodide is a currently registered pesticide.Definition
ChEBI: A member of the class of iodomethanes that is methane in which one of the hydrogens is replaced by iodine.Allgemeine Beschreibung
A colorless liquid that turns brown on exposure to light. Denser than water. Contact may irritate skin, eyes and mucous membranes. Very toxic by ingestion, inhalation and skin absorption.Air & Water Reaktionen
Soluble in water. Sinks and slowly decomposes in water forming poisonous vapor cloud of HI.Reaktivit?t anzeigen
Halogenated aliphatic compounds, such as Iodomethane, are moderately or very reactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Low molecular weight haloalkanes are highly flammable and can react with some metals to form dangerous products. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, alkylphosphines, nitrides, azo/diazo compounds, alkali metals (sodium), and epoxides.Hazard
Toxic by ingestion, inhalation, and skinabsorption; narcotic, irritant to skin. Eye damageand central nervous system impairment. Question-able carcinogen.Health Hazard
Inhalation of vapor causes lung congestion and pulmonary edema. Higher concentrations causes rapid narcosis and death. Contact with liquid irritates eyes and burns skin.Brandgefahr
Noncombustible. High vapor pressure may cause containers to burst at elevated temperatures.Flammability and Explosibility
Noncombustible. High vapor pressure may cause containers to burst at elevated temperatures.Sicherheitsprofil
Confirmed carcinogen with experimental neoplastigenic and tumorigenic data. A poison by ingestion, intraperitoneal, and subcutaneous routes. Moderately toxic by inhalation and skin contact. A human skin irritant. Human mutation data reported. A strong narcotic and anesthetic. Explosive reaction with trialkylphosphines, silver chlorite. Violent reaction with oxygen (at 3000C), sodium. When heated to decomposition it emits toxic fumes of I-.m?gliche Exposition
Methyl iodide is used in fire extinguishers; as an intermediate in the manufacture of pharmaceuticals and some pesticides.Carcinogenicity
Druckrey et al. reported local sarcomas following weekly subcutaneous injection in BD strain rats. Strain A mice (a susceptible strain) that were injected with methyl iodide were reported to have a slight but significant increase in the number of lung tumors per mouse. Poirer et al. administered iodomethane dissolved in tricaprylin to male and female strain A mice (10/sex/dose) three times weekly by intraperitoneal injection. There was a marginally statistically significant trend for increased lung tumors in treated mice but the outcome was considered equivocal: no clear dose–response relationship and occurrence of spontaneous tumors in untreated mice.Under the 2005 Guidelines for Carcinogen Risk Assessment (121), the lack of available evidence suggests that there is “inadequate information to assess the carcinogenic potential for iodomethane.”
An early evaluation by the IARC classified iodomethane as carcinogenic in rats. Two subsequent evaluations (123, 124) determined that there is limited evidence for carcinogenicity in experimental animals and the compound is not classifiable regarding carcinogenicity to humans. ACGIH has also reviewed iodomethane carcinogenicity and classified it as category A2, suspected human carcinogen; however, the A2 classification was withdrawn in 1996. Iodomethane was delisted as a carcinogen in the NTP 5th Annual Report on Carcinogens on the basis of the 1986 IARC reevaluation. NTP has not tested iodomethane for carcinogenicity. The State of California determined under Proposition 65 that methyl iodide is a carcinogen, based on the 1977 IARC evaluation. Neither a Toxicological Profile nor an Environmental Health Criteria Monograph has been published.
Environmental Fate
Chemical/Physical. Anticipated products from the reaction of methyl iodide with ozone or OH radicals in the atmosphere are formaldehyde, iodoformaldehyde, carbon monoxide, and iodine radicals (Cupitt, 1980). With OH radicals, CH2, methyl radical, HOI and water are possible reaction products (Brown et al., 1990). The estimated half-life of methyl iodide in the atmosphere, based on a measured rate constant for the vapor phase reaction with OH radicals, ranges from 535 h to 32 wk (Garraway and Donovan, 1979).Hydrolyzes in water forming methyl alcohol and hydriodic acid. The estimated half-life in water at 25 °C and pH 7 is 110 d (Mabey and Mill, 1978). At 70 °C, the hydrolysis rate was determined to be 3.2 x 10-5/sec which is equivalent to a half-life of 6 h. (Glows and Wren, 2003). May react with chlorides in seawater to form methyl chloride (Zafiriou, 1975).
Versand/Shipping
UN2644 Methyl iodide, Hazard Class: 6.1; Labels: 6.1-Poison Inhalation Hazard, Inhalation Hazard Zone Bl?uterung methode
Methyl iodide deteriorates rapidly with liberation of iodine if exposed to light. It is usually purified by shaking with dilute aqueous Na2S2O3 or NaHSO3 until colourless, then washing with water, dilute aqueous Na2CO3, and more water, drying with CaCl2 and distilling. It is stored in a brown bottle away from sunlight in contact with a small amount of mercury, powdered silver or copper. (Prolonged exposure of mercury to methyl iodide forms methylmercuric iodide.) Methyl iodide can be dried further using CaSO4 or P2O5. An alternative purification is by percolation through a column of silica gel or activated alumina, then distillation. The solution can be degassed by using a repeated freeze-pump-thaw cycle. [Beilstein 1 IV 87.]Inkompatibilit?ten
May form explosive mixture with air. Slowly reacts with water forming poisonous hydrogen iodide. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Violent reaction with strong oxidizers, strong reducing agents, strong bases; trialkylphosphines, silver chlorite; calcium, oxygen, sodium. Decomposes @ 270C. Halogenated aliphatic compounds are moderately or very reactive. Halogenated organics generally become less reactive as more of their hydrogen atoms are replaced with halogen atoms. Low molecular weight haloalkanes are highly flammable and can react with some metals to form dangerous products. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, alkylphosphines, nitrides, azo/diazo compounds, alkali metals (sodium), and epoxidesWaste disposal
Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform to EPA regulations governing storage, transportation, treatment, and waste disposalMethyljodid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Androst-5-ene-3,17-diol-17-propanoic acid lactone
Canrenon
2-Phenylpropan-2-ol
4-CHLORO-N-METHYLPYRIMIDIN-2-AMINE
3,3-DIMETHYLISOBENZOFURAN-1(3H)-ONE
4(3H)-Pyrimidinone, 5-methyl-2-(methylthio)-
(1-METHYL-1H-BENZIMIDAZOL-2-YL)METHYLAMINE
5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE
2-METHOXY-5-NITROBENZALDEHYDE
2,2-DIMETHYLCYCLOPENTANONE
Clarithromycin
4,6-Dimethyl-2-methylmercapyrimidine
2-IODO-3-METHOXY-6-METHYLPYRIDINE
1-Iod-2,2-dimethylpropan
1-[2-(Dimethylamino)ethyl]-1,2-dihydro-5H-tetrazol-5-thion
7-Methoxycumarin
Benzyltrimethylammoniumiodid
(R)-(-)-Methyl glycidyl ether
1 2-DIMETHYLPYRIDINIUM IODIDE 97
2,5-Dihydro-5-thioxo-1H-tetrazol-1-methansulfonsure
Androst-5-ene-3,17-diol-17-propiolic acid potassium salt
3,17-Dihydroxyandrost-5-ene-17-propionic acid phtassium salt
BENZYL-(2-METHYLSULFANYL-PYRIMIDIN-4-YL)-AMINE
3,17-Dihydroxyandrost-5-ene-17-propiolic acid
GRANISETRON-D3
Astemizol
3-Methyl-4-nitroanisol
fluorocarbon sulfactant FC-3
3-Oxopregn-4-en-21,17α-carbolacton
Prazosin
4-METHYL-2-(METHYLSULFANYL)PYRIMIDINE
5-METHOXY-2-METHYLPYRIDINE
Methandriol
3,5-DIMETHYL-3H-IMIDAZOLE-4-CARBOXYLIC ACID ETHYL ESTER
4-Chlor-2-methylthiopyrimidin
Fluorocaruor surfactant FC-4
2-Bromo-3-methoxy-6-methylpyridine
(S)-(+)-Methyl glycidyl ether
2,2-DIMETHYLCYCLOHEXANONE
1-(3-Methylpyrazinyl)ethan-1-on
Methyljodid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 411)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
Hebei Chuanghai Biotechnology Co., Ltd | +86-15531157085 +86-15531157085 |
abby@chuanghaibio.com | China | 8807 | 58 |
Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12821 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 |
Mandy@hangyubiotech.com | China | 10986 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20254 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21631 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 33024 | 60 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 |
info@tnjchem.com | China | 2986 | 55 |
Biochempartner | 0086-13720134139 |
candy@biochempartner.com | CHINA | 965 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28172 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22963 | 58 |
74-88-4(Methyljodid)Verwandte Suche:
Tribenuron methyl
Methylacrylat
Methylsalicylat
Iod
3,8-Diamino-5-(3-(diethylmethylam-monio)-propyl)-6-phenylphenanthri-diniumdiiodid
Kresoxim-methyl
Methanol
Methyl-4-hydroxybenzoat
Basic Violet 1
Kupferiodid
Kaliumiodat
Hydrogeniodid
Acetonitril
Methyl
Diiodmethan
Chloriodomethan
Trifluoromethyl iodide
α,α,α-Trifluor-2-iodtoluol
- 10domethane
- Halon 10001
- Iodomethane, 2M solution in tert-butyl methyl ether
- Iodomethane, stabilized, 99%
- Iodomethane,99%,stabilized
- Iodomethane, Stab. With Copper
- --- D/C 09 --- Methyl iodide 1g [74-88-4]
- Iodomethane, 99+%, stab. with copper
- Iodomethane, 99%, stab. with copper or silver
- METHYL IODIDE extrapure(stabilized)
- Iodomethane solution, Methyl iodide
- Iodomethane2M solution in tert-butyl methyl etherAcroSeal§3
- Iodomethane (stabilized with Copper chip)
- 0.1% METHANOL-13C + 0.3 MG/ML
- METHYL IODIDE + COPPER WIRE
- IodoMethane, 2M soln. in tert-butyl Methyl ether
- halon10001
- Iodmethan
- Iodometano
- iodo-methan
- Iodure de methyle
- ioduredemethyle
- ioduredemethyle(french)
- Jodmethan
- Jod-methan
- Joodmethaan
- Methane,iodo-
- Methyliodide(CH3I)
- methyliodide(iodomethane)
- Methyljodid
- Methyljodide
- Metylu jodek
- metylujodek
- metylujodek(polish)
- Monoiodomethane
- Monoioduro di metile
- monoiodurodimetile
- Rcra waste number U138
- rcrawastenumberu138
- Iodomethane,99+%
- Methyl iodide? METHYL IODIDE (IODOMETHANE)
- IODOMETHANE 1X1ML MEOH/WATER 80/20 2000U G/ML
- IODOMETHANE SOLUTION, ~2.0 M IN TERT-BUT YL METHYL ETHER
- IODOMETHANE REAGENTPLUSTM 99.5%
- IODOMETHANE, REDIST., STAB. WITH SILVER WOOL
- IODOMETHANE 100MG NEAT
- IODOMETHANE REAGENTPLUS(TM) 99%
- IODOMETHANE, 2.0M SOLUTION IN TERT-BUTYL METHYL ETHER
- IODOMETHANE, REAGENTPLUS, 99%
- IODOMETHANE STABILIZED WITH SILVER FOIL
- IODOMETHANE, REAGENTPLUS, 99.5%
- IODOMETHANE, STAB. WITH SILVER WOOL
- MethylIodideForSynthesis
- IodoMethane, 2M solution in tert-butyl Methyl ether, AcroSeal
- IODOMETHANE (STABILISED WITH SILVER) FOR
- Iodomethane solution 2.0 M in tert-butyl methyl ether, contains copper as stabilizer
- Iodomethane, 99.5%, stabilized
- Methyl iodide≥ 99% (GC)