Trospiumchlorid
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- CAS-Nr.
- 10405-02-4
- Bezeichnung:
- Trospiumchlorid
- Englisch Name:
- Trospium chloride
- Synonyma:
- Trospium;Trosupium Chloride;Sanctura;asxvii;keptan;spasmex;spasmo3;relaspium;Spasmo-lyt;trospiuM-D8
- CBNumber:
- CB6481397
- Summenformel:
- C25H30ClNO3
- Molgewicht:
- 427.96
- MOL-Datei:
- 10405-02-4.mol
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Trospiumchlorid Eigenschaften
- Schmelzpunkt:
- 266-268°C
- storage temp.
- Inert atmosphere,2-8°C
- L?slichkeit
- Very soluble in water, freely soluble in methanol, practically insoluble in methylene chloride.
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Merck
- 14,9786
- InChIKey
- RVCSYOQWLPPAOA-QKYUOBHYSA-M
- SMILES
- [N+]12(CCCC1)[C@@]1([H])CC[C@]2([H])C[C@@H](C1)OC(=O)C(O)(C1=CC=CC=C1)C1C=CC=CC=1.[Cl-] |&1:5,9,12,r|
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| RTECS-Nr. |
WH1424000 |
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| HS Code |
2939800000 |
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| Toxizit?t |
Soly in water: ~1 g/2 ml. LD50 in mice (mg/kg): 12.3 i.v. (Antweiler) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
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Trospiumchlorid Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Trospium chloride (Sanctura) is an antimuscarinic that has been used in Europe for the management of OAB symptoms for over 30 years.Trospium chloride's chemical structure is such that it is unlikely to penetrate the brain and thus does not appear to affect cognitive function. Trospium chloride is usually administered orally twice a day in 20mg. Trospium chloride should be taken 1 hour before meals or on an empty stomach. It is not well absorbed if taken with food.An advantage of this medication is that it has little potential interaction with other medications.
Chemische Eigenschaften
White to Off-White Crystalline Solid
Verwenden
Tropine derivative with anticholinergic activity, Trospium chloride can be used as Antispasmodic and used in treatment of urinary incontinence
Allgemeine Beschreibung
Trospium chloride, 3α-benziloyloxynortropane-8-spiro-1'-pyrrolidinium chloride, (Sanctura) was available in Europe for almost 20 years before gainingapproval in the United States in May 2004. Much likeoxybutynin, it too is a competitive antagonist for muscarinicreceptors and is used to manage overactive bladder. Thequaternary amine reduces the likelihood that this agent willcross the blood-brain barrier. In addition, it has a limitedmetabolic profile, largely a result of its highly water-solublecharacteristics.
Trospiumchlorid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Trospiumchlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 325)Lieferanten
10405-02-4(Trospiumchlorid)Verwandte Suche:
- (1a,3,5a)-3-[(2-Hydroxy-2,2-diphenylacetyl)oxy]-spiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium] Chloride
- 5-alpha-h-nortropane-8,1’-pyrrolidinium),3-alpha-hydroxy-spiro(1-alpha-chl
- 8-alpha-benziloyloxy-6,10-ethano-5-azoniaspiro(4.5)decanechloride
- asxvii
- azoniaspiro(3-alpha-benziloyloxy-nortropan-8,1’-pyrrolidine)-chloride
- azoniaspirocompoundxvii
- keptan
- Trosipium Chloride
- Spiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium], 3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-, chloride (1:1), (1a,3b,5a)-
- Trospium Chloride (100 mg)
- trospiuM-D8
- TrospiuM chloride (Sanctura)
- (1α,3β,5α)-3-[(2-Hydroxy-2,2-diphenylacetyl)oxy]-spiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidiniuM] Chloride
- (1α,3β,5α)-3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-Spiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium],chloride (1:1)
- Trospium chloride, >=99%
- oride,benzilate
- relaspium
- spasmex
- spasmo3
- TROSPIUM CHLORIDE
- (1a,3b,5a)-3-[(2-Hydroxy-2,2-diphenylacetyl)oxy]-spiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium] Chloride
- Azoniaspiro
- Azoniaspiro(3a-benziloyloxynortropane-8,1'-pyrrolidine) chloride
- Benzilic acid, ester with 3a-hydroxyspiro[1aH,5aH-nortropane-8,1'-pyrrolidinium] chloride (8CI)
- Spasmo-lyt
- Spiro[1aH,5aH-nortropane-8,1'-pyrrolidinium], 3a-hydroxy-, chloride, benzilate (8CI)
- Spiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium], 3-[(hydroxydiphenylacetyl)oxy]-, chloride, (1a,3b,5a)- (9CI)
- Trospiumchlorid
- TROSPIUM CHLORDE
- 2-hydroxy-2,2-diphenylacetic acid [(1S,5R)-3-spiro[8-azoniabicyclo[3.2.1]octane-8,1'-azolidin-1-ium]yl] ester chloride
- Trospium chloride CRS
- rel-(1R,3r,5S)-3-(2-Hydroxy-2,2-diphenylacetoxy)spiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-1'-ium chloride
- Trospium chloride USP/EP/BP
- Trospium chlorideQ: What is
Trospium chloride Q: What is the CAS Number of
Trospium chloride Q: What is the storage condition of
Trospium chloride Q: What are the applications of
Trospium chloride
- Trospium-d8 chlorideQ: What is
Trospium-d8 chloride Q: What is the CAS Number of
Trospium-d8 chloride Q: What is the storage condition of
Trospium-d8 chloride Q: What are the applications of
Trospium-d8 chloride
- Trospium Chloride (1699300)
- Sanctura
- Trospium
- Trosupium Chloride
- 13C6]-Trospium chloride salt
- rel-(1R,3r,5S)-3-(2-Hydroxy-2,2-diphenylacetoxy)spiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-1'-ium chloride
- 10405-02-4
- 10405024
- C25H30ClNO3
- C25H30NO3Cl
- C25H30NO3
- AGRI-MEK
- Intermediates & Fine Chemicals
- Pharmaceuticals
- 10405-02-4
