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Cholinchlorid

Choline chloride Struktur
67-48-1
CAS-Nr.
67-48-1
Bezeichnung:
Cholinchlorid
Englisch Name:
Choline chloride
Synonyma:
Choline Chloride pure;CHOLINE CHLORID;CHOLINE CHLORIDE POWDER;Choline Chloride 60% Corn COB;Lipotril;BIOCOLINA;HEPACHOLINE;HOEtN1,1,1Cl;Cholinchlorid;Cholinii chloridum
CBNumber:
CB6166667
Summenformel:
C5H14ClNO
Molgewicht:
139.62
MOL-Datei:
67-48-1.mol

Cholinchlorid Eigenschaften

Schmelzpunkt:
302-305 °C (dec.) (lit.)
Dichte
1.0238 (rough estimate)
Brechungsindex
1.5400 (estimate)
FEMA 
4500 | Choline chloride (Also Includes Choline)
storage temp. 
Sealed in dry,Room Temperature
L?slichkeit
H2O: 1 M, clear, colorless
Aggregatzustand
Adhering Crystals
Farbe
White
PH
5.0-7.5 (25℃, 1M in H2O)
Geruch (Odor)
sl. odor of trimethylamine
Wasserl?slichkeit
soluble
Sensitive 
Hygroscopic
maximale Wellenl?nge (λmax)
λ: 260 nm Amax: 0.015
λ: 280 nm Amax: 0.010
JECFA Number
2003
Merck 
14,2206
BRN 
3563126
Stabilit?t:
Stable. Incompatible with strong oxidizing agents, moisture. Store under a dry atmosphere.
InChIKey
SGMZJAMFUVOLNK-UHFFFAOYSA-M
LogP
-3.70
CAS Datenbank
67-48-1(CAS DataBase Reference)
NIST chemische Informationen
Choline chloride(67-48-1)
EPA chemische Informationen
Choline chloride (67-48-1)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/37/38
S-S?tze: 26-36
WGK Germany  1
RTECS-Nr. KH2975000
3-9
TSCA  Yes
HS Code  29212900
Giftige Stoffe Daten 67-48-1(Hazardous Substances Data)
Toxizit?t LD50 in rats (g/kg): 0.400 i.p.; 6.64 orally (Hartung, Cornish)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H303 May be harmfulif swallowed Acute toxicity,oral Category 5 P312
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P304+P340 BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

Cholinchlorid Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD

WEISSE HYGROSKOPISCHE KRISTALLE

CHEMISCHE GEFAHREN

Beim Verbrennen Bildung giftiger und ?tzender Rauche mit Chlorwasserstoff. Reagiert mit starken Oxidationsmitteln.

ARBEITSPLATZGRENZWERTE

TLV nicht festgelegt (ACGIH 2005).
MAK nicht festgelegt (DFG 2005).

INHALATIONSGEFAHREN

Eine bel?stigende Partikelkonzentration in der Luft kann beim Dispergieren schnell erreicht werden.

LECKAGE

Verschüttetes Material in Beh?ltern sammeln; falls erforderlich durch Anfeuchten Staubentwicklung verhindern.

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Chemische Eigenschaften

White crystalline powder

Application

Choline chloride has been used:
as a component of choline acetyltransferase (ChAT) buffer and for choline uptake in cultured human neuroblastoma (SK-N-SH) cells
for choline standard curve generation for quantifying phospholipase D (PLD) activity
as a component of slice solution for the dissection of entorhinal-hippocampal brain slices

Definition

ChEBI: Choline chloride is a quaternary ammonium salt with choline cation and chloride anion. It has a role as an animal growth promotant. It is a chloride salt and a quaternary ammonium salt. It contains a choline.

benefits

choleretic, lipotropic, hepatoprotectant

Allgemeine Beschreibung

Choline chloride appears as white crystals. Practically neutral aqueous solution(NTP, 1992). It is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.

Air & Water Reaktionen

Deliquescent. Very soluble in water.

Reaktivit?t anzeigen

An acidic organic salt. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.

Brandgefahr

Choline chloride is relatively nonflammable.

Sicherheitsprofil

Poison by intraperitoneal and intravenous routes. Moderately toxic experimentally by ingestion and subcutaneous routes. Mutation data reported. A lipotropic agent which induces the reduction in fats contained in the liver. When heated to decomposition it emits toxic fumes of Cl-, SOx and NOx. See also CHOLINE.

l?uterung methode

Extremely deliquescent. Check purity by AgNO3 titration or by titration of OH-base after passage through an anion-exchange column. Crystallise it from absolute EtOH, or EtOH/Et2O, dry it under vacuum and store it in a vacuum desiccator over P2O5 or Mg(ClO4)2. [Beilstein 4 IV 1443.]

Cholinchlorid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Cholinchlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 838)Lieferanten
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67-48-1(Cholinchlorid)Verwandte Suche:


  • Choline chloride >=97.0% (AT)
  • Choline chloride, 99% 500GR
  • Choline chloride, 99% 50GR
  • chloridedecholine(french)
  • CHOLINE (CL)
  • cholinechlorhydrate
  • cholinehydrochloride
  • choliniumchloride
  • Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, chloride
  • Ethanaminium,2-hydroxy-N,N,N-trimethyl-,chloride
  • Ethanaminium,2-hydroxy-N,N-N-trimethyl-,chloride
  • Hormocline
  • HYDROXYETHYLTRIMETHYLAMMONIUM CHLORIDE
  • CHOLINE CHLORIDE
  • N-(2-HYDROXYETHYL)TRIMETHYLAMMONIUM CHLORIDE
  • Choline chloride Vetec(TM) reagent grade, >=98%
  • Choline chloride, FCC Grade
  • CHLORIDE CHOLINE
  • CHOLINE CHLORIDE, DAB
  • CHOLINE CHLORIDE, REAGENTPLUS, >=99%
  • CHOLINE CHLORIDE 3X CRYST
  • CHOLINE CHLORIDE CELL CULTURE TESTED
  • CHOLINE CHLORIDE APPROX. 99%
  • CHOLINE CHLORIDE BIOSYNTH
  • CholineChloride50%
  • CholineChloride60%Min.
  • CholineChloride,>99%
  • ChlolineChloride
  • CholineChlorideExtraPure99%
  • CHOLINE CHLORIDE EXTRA PURE 99%
  • CHOLINE CHLORIDE, SOLUTION
  • CHOLINE CHLORIDE, PHARMA
  • Choline Chloride (200 mg)
  • Choline chloride (Also Includes Choline)
  • Choline Chloride, Animal-Free
  • (2-hydroxyethyl)trimethyl-ammoniuchloride
  • (beta-Hydroxyethyl)trimethylammonium chloride
  • (beta-hydroxyethyl)trimethylammoniumchloride
  • 2-hydroxy-n,n,n-trimethyl-ethanaminiuchloride
  • Ammonium, (2-hydroxyethyl)trimethyl-, chloride
  • Bilineurin chloride
  • bilineurinchloride
  • Biocoline
  • Chloride de choline
  • chloridedecholine
  • Luridin chloride
  • luridinchloride
  • Neocolina
  • Paresan
  • Trimethyl(2-hydroxyethyl)ammonium chloride
  • trimethyl(2-hydroxyethyl)ammoniumchloride
  • N-(2-hydroxyethyl)-N,N,N-trimethylammonium chloride
  • N,N,N-Trimethyl-2-hydroxyethylammonium chloride
  • Choline chlorohydrate
  • Choline chloride[(2-Hydroxyethyl)trimethylammonium chloride]
  • Choline chloride, 98+%
  • Choline chloride (feed grade)
  • Actiron CC 6
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