69049-73-6
69049-73-6 結(jié)構(gòu)式
基本信息
尼多克羅
萘多羅米
來(lái)多克羅米
哮喘預(yù)防藥
9-乙基-6,9-二氫-4,6-二氧代-10-丙基-4H-吡喃并[3,2-G]喹啉-2,8-二甲酸
9-乙基-6,9-二氫-4,6-二氧代-10-丙基-4H-吡喃并[3,2-G]喹啉-2,8-二羧酸
FPL-59002
NedocroMi
NEDOCROMIL
Nedocromilo
FPL-59002KP
Nedocromilum
Tilarin：Tilade
Nedocromilum [latin]
Nedocromilo [spanish]
物理化學(xué)性質(zhì)
奈多羅米二鈉鹽(奈多羅米鈉，Nedocromil Disodium)：C19H15NO7Na2。[69049-74-7]。淡黃色結(jié)晶性粉末。
應(yīng)用領(lǐng)域
制備方法
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/08/19 | HY-13448 | 尼多克羅 Nedocromil | 69049-73-6 | 5mg | 800元 |
| 2024/08/19 | HY-13448 | 尼多克羅 Nedocromil | 69049-73-6 | 10mM * 1mLin DMSO | 880元 |
| 2024/08/19 | HY-13448 | 尼多克羅 Nedocromil | 69049-73-6 | 10mg | 1300元 |
常見問題列表
|
LTC 4
|
PGD 2
|
Histamine
|
Nedocromil inhibits the release of histamine, LTC 4 , and PGD 2 from mast cells challenged with antigen (with IC 30 values of 2.1 μM, 2.3 μM, and 1.9 μM, respectively) and with anti-human IgE (IC 30 values of 4.7 μM, 1.3 μM, and 1.3 μM, respectively).
Nedocromil-treated diabetic mice show significantly improved heart function compared with controls. The contractility and relaxation forces show similar improvements. However, the cardiac function of Nedocromil-treated diabetic mice remains significantly impaired when compared with normal mice. Nedocromil can significantly improve cardiac function in mice with diabetic cardiomyopathy, but the treatment cannot restore normal function.