329-89-5
329-89-5 結(jié)構(gòu)式
基本信息
2-氨基吡啶-5-甲酰胺
6-氨基-3-吡啶甲酰胺
6-氨基尼克酰胺
6-氨基維生素PP
6-AMINO-3-PYRIDINECARBOXAMIDE
6-AMINONICOTINAMIDE
6-AMINOPYRIDINE-3-CARBOXAMIDE
2-Amino-5-carbamoylpyridine
3-Pyridinecarboxamide, 6-amino-
6-amino-3-pyridinecarboxamid
6-amino-nicotinamid
6-Aminonicotinic acid amide
6-aminonicotinicacidamide
6-Amino-nicotinsaeureamid
6-Aminonikotinsaeureamid
6-AN
6-ANA
Aminonicotinamide
FDA 0121
fda0121
NSC 21206
nsc21206
U-8774
物理化學(xué)性質(zhì)
329-89-5(安全特性,毒性,儲(chǔ)運(yùn))
知名試劑公司產(chǎn)品信息
6-Aminonicotinamide,>99.0%(T)(329-89-5)
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/11/08 | L06692 | 6-氨基煙酰胺, 99% 6-Aminonicotinamide, 99% | 329-89-5 | 1g | 739元 |
| 2024/11/08 | L06692 | 6-氨基煙酰胺, 99% 6-Aminonicotinamide, 99% | 329-89-5 | 5g | 2914元 |
| 2024/11/08 | 10415 | 6-氨基煙酰胺 6-Aminonicotinamide, 98%, Thermo Scientific Chemicals | 329-89-5 | 1g | 1330元 |
常見問題列表
| Target | Value |
|
G6PD
(Cell-free assay) | 0.46 μM(Ki) |
6-Aminonicotinamide (100 nM; 7 days) causes a significant decrease in the human AR+, hormone-sensitive prostate cancer cell lines LNCaP and LAPC4, as well as the CRPC-derivative C4-2 and 22Rv1 cell models. 6-Aminonicotinamide (100?nM ± 10?nM R1881 as indicated for 3 days) increases both basal- and R1881-mediated ROS levels, suggesting 6-Aminonicotinamide is blocking the cells' antioxidant defense. 6-Aminonicotinamide also increases ROS levels in C4-2 cells.
6-Aminonicotinamide (20 mg/kg; i.p.; thress times; days 1, 10 or 11, and 21) alone induces a small but significant tumor growth delay (4.3+/-0.8 days). Treatment with 6-Aminonicotinamide followed by radiation induces a tumor growth delay of 57.0+/-3.8 days in CD8F1 breast tumor model.