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ChemicalBook--->CAS DataBase List--->7423-55-4

7423-55-4

7423-55-4 Structure

7423-55-4 Structure
IdentificationMore
[Name]

3-Maleimidopropionic acid
[CAS]

7423-55-4
[Synonyms]

3-(2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-1-YL)PROPANOIC ACID
3-(2,5-DIOXO-2,5-DIHYDRO-PYRROL-1-YL)-PROPIONIC ACID
3-MALEIMIDOPROPIONIC ACID
AKOS BC-0729
BETA-MALEIMIDOPROPIONIC ACID
BMPA
MALEOYL-BETA-ALA-OH
MPA
MPA-OH
N-(2-CARBOXYETHYL)MALEIMIDE
N-BETA-MALEIMIDOPROPIONIC ACID
N-MALEOYL-BETA-ALANINE
RARECHEM AL CD 0912
B-MALEIMIDOPROPIONIC ACID
3-Maleinimidopropionicacid
3-Maleimidopropionic
n-maleoyl-β-alanine
3-MALEIMIDOPROPIONOIC ACID DIHYDRATE
3-(2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-prop
3-Maleimidopropionic acid, N-(2-Carboxyethyl)maleimide
[EINECS(EC#)]

616-069-0
[Molecular Formula]

C7H7NO4
[MDL Number]

MFCD00043030
[Molecular Weight]

169.13
[MOL File]

7423-55-4.mol
Chemical PropertiesBack Directory
[Appearance]

White to Pale Yellow Solid
[Melting point ]

103-106 °C (lit.)
[Boiling point ]

382.5±25.0 °C(Predicted)
[density ]

1.473±0.06 g/cm3(Predicted)
[storage temp. ]

-15°C
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

4.18±0.10(Predicted)
[color ]

White
[Water Solubility ]

Soluble in methanol, dimethyl formamide, alcohol and dimethyl sulfoxide. Slightly soluble in water.
[Sensitive ]

Moisture Sensitive
[Usage]

A sulfhydryl reactive heterobifunctional crosslinking reagent.
[Detection Methods]

HPLC,NMR
[BRN ]

1528952
[InChIKey]

IUTPJBLLJJNPAJ-UHFFFAOYSA-N
[CAS DataBase Reference]

7423-55-4(CAS DataBase Reference)
[Storage Precautions]

Moisture sensitive;Store under nitrogen
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[WGK Germany ]

3
[F ]

10-21
[HS Code ]

29252900
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Acetic acid-->Toluene-->Maleic anhydride-->2,3-DICHLORO-5,8-DIHYDROXY-1,4-NAPHTHOQUINONE-->β-Alanine-->2,3-Pentanedione-->CIS-5-AZA-4-OXO-OCT-2-EN-DIOIC ACID
[Preparation Products]

2,5-Dimethylfuran-->Maleimide-PEG4-NHS Ester
Hazard InformationBack Directory
[Description]

3-Maleimidopropionic acid contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
[Chemical Properties]

White to Pale Yellow Solid
[Uses]

A sulfhydryl reactive heterobifunctional crosslinking reagent.
[General Description]

N-Maleoyl-β-alanine (3-maleimidopropanoic acid) is an aliphatic N-substituted maleimide. It is one of the component of the stabilizing solution for EC145 (a folate-targeted vinca alkaloid conjugate) used in rodent pharmacokinetic studies.
Spectrum DetailBack Directory
[Spectrum Detail]

3-Maleimidopropionic acid(7423-55-4)MS
3-Maleimidopropionic acid(7423-55-4)IR1
3-Maleimidopropionic acid(7423-55-4)IR2
3-Maleimidopropionic acid(7423-55-4)Raman
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

7423-55-4(sigmaaldrich)
[TCI AMERICA]

3-Maleimidopropionic Acid,>97.0%(GC)(T)(7423-55-4)
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