Identification | More | [Name]
3-Maleimidopropionic acid | [CAS]
7423-55-4 | [Synonyms]
3-(2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-1-YL)PROPANOIC ACID 3-(2,5-DIOXO-2,5-DIHYDRO-PYRROL-1-YL)-PROPIONIC ACID 3-MALEIMIDOPROPIONIC ACID AKOS BC-0729 BETA-MALEIMIDOPROPIONIC ACID BMPA MALEOYL-BETA-ALA-OH MPA MPA-OH N-(2-CARBOXYETHYL)MALEIMIDE N-BETA-MALEIMIDOPROPIONIC ACID N-MALEOYL-BETA-ALANINE RARECHEM AL CD 0912 B-MALEIMIDOPROPIONIC ACID 3-Maleinimidopropionicacid 3-Maleimidopropionic n-maleoyl-β-alanine 3-MALEIMIDOPROPIONOIC ACID DIHYDRATE 3-(2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-prop 3-Maleimidopropionic acid, N-(2-Carboxyethyl)maleimide | [EINECS(EC#)]
616-069-0 | [Molecular Formula]
C7H7NO4 | [MDL Number]
MFCD00043030 | [Molecular Weight]
169.13 | [MOL File]
7423-55-4.mol |
Chemical Properties | Back Directory | [Appearance]
White to Pale Yellow Solid | [Melting point ]
103-106 °C (lit.) | [Boiling point ]
382.5±25.0 °C(Predicted) | [density ]
1.473±0.06 g/cm3(Predicted) | [storage temp. ]
-15°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
4.18±0.10(Predicted) | [color ]
White | [Water Solubility ]
Soluble in methanol, dimethyl formamide, alcohol and dimethyl sulfoxide. Slightly soluble in water. | [Sensitive ]
Moisture Sensitive | [Usage]
A sulfhydryl reactive heterobifunctional crosslinking reagent. | [Detection Methods]
HPLC,NMR | [BRN ]
1528952 | [InChIKey]
IUTPJBLLJJNPAJ-UHFFFAOYSA-N | [CAS DataBase Reference]
7423-55-4(CAS DataBase Reference) | [Storage Precautions]
Moisture sensitive;Store under nitrogen |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [F ]
10-21 | [HS Code ]
29252900 |
Hazard Information | Back Directory | [Description]
3-Maleimidopropionic acid contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. | [Chemical Properties]
White to Pale Yellow Solid | [Uses]
A sulfhydryl reactive heterobifunctional crosslinking reagent. | [General Description]
N-Maleoyl-β-alanine (3-maleimidopropanoic acid) is an aliphatic N-substituted maleimide. It is one of the component of the stabilizing solution for EC145 (a folate-targeted vinca alkaloid conjugate) used in rodent pharmacokinetic studies. |
|
|