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ChemicalBook--->CAS DataBase List--->955094-26-5

955094-26-5

955094-26-5 Structure

955094-26-5 Structure
IdentificationBack Directory
[Name]

α-Maleimidopropionyl-ω-succinimidyl-2(ethylene glycol)
[CAS]

955094-26-5
[Synonyms]

SM(PEG)2
Mal-PEG2-NHS
Mal-NH-PEG2-NHS
Maleimide-PEG2-NHS
Mal-amido-PEG2-NHS
Maleimide-PEG2-NHS Ester
MAL-NH-PEG2-CH2CH2COONHS
MaleiMide-NH-PEG2-NHS Ester
MaleiMide-PEG2-suciniMidyl ester
Maleimide-PEG2-NHS Ester (2mg*5)
Maleimide-PEG?-succinimidyl ester
MaleiMide-PEG2-succiniMidyl ester
MaleiMide-NH-PEG2-CH2CH2COONHS Ester
Maleimide-PEG2-succinimidyl ester 99%
Maleimidopropionyl-PEG2-CH2CH2COONHS Ester
Maleimide-PEG2-succinimidyl ester
α-Maleimidopropionyl-ω-succinimidyl-2(ethylene glycol)
alpha-MaleiMidopropionyl-oMega-succiniMidyl-2(ethylene glycol)
N-Succinimidyl 13-Maleimido-11-oxo-4,7-dioxa-10-azatridecanoate
13-Maleimido-11-oxo-4,7-dioxa-10-azatridecanoic Acid N-Succinimidyl Ester
2,5-Doxopyrrolidin-1-yl 3-[2-[2-[3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamid
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]propanoate
2,5-dioxopyrrolidin-1-yl 3-(2-(2-(3-(2,5-dioxo-1H-pyrrol-1(5H)-yl)propanamido)ethoxy)ethoxy)propanoate
2,5-Dioxopyrrolidin-1-yl 3-(2-(2-(3-(2,5-dioxo-2h-pyrrol-1(5h)-yl)propanamido)ethoxy)ethoxy)propanoate
2,5-dioxopyrrolidin-1-yl 3-(2-(2-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido)ethoxy)ethoxy)propanoate
3-[2-[2-[[3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]propanoic acid 2,5-dioxo-1-pyrrolidinyl ester
Propanoic acid, 3-[2-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
[Molecular Formula]

C18H23N3O9
[MDL Number]

MFCD11041137
[MOL File]

955094-26-5.mol
[Molecular Weight]

425.39
Chemical PropertiesBack Directory
[Melting point ]

90.0 to 94.0 °C
[density ]

1.41±0.1 g/cm3(Predicted)
[storage temp. ]

?20°C
[form ]

powder to crystal
[pka]

15.00±0.46(Predicted)
[color ]

White to Light yellow
[InChI]

InChI=1S/C18H23N3O9/c22-13(5-8-20-14(23)1-2-15(20)24)19-7-10-29-12-11-28-9-6-18(27)30-21-16(25)3-4-17(21)26/h1-2H,3-12H2,(H,19,22)
[InChIKey]

TZPDZOJURBVWHS-UHFFFAOYSA-N
[SMILES]

C(ON1C(=O)CCC1=O)(=O)CCOCCOCCNC(=O)CCN1C(=O)C=CC1=O
Safety DataBack Directory
[WGK Germany ]

3
[HS Code ]

29280000
Hazard InformationBack Directory
[Description]

Mal-amido-PEG2-NHS is a PEG linker containing a maleimide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
[Uses]

Maleimide-PEG2-NHS Ester(955094-26-5) is a heterobifunctional crosslinker with short ethylene oxide spacer for linking amine- to sulfhydryl-containing compounds or biomolecules. Maleimide functional group will react with sulfhydryls and the succinimidyl ester group will react with amines. Spacer length is 17.6 angstroms.
[reaction suitability]

reaction type: Pegylations
reagent type: cross-linking reagent
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