| Identification | More | [Name]
Chloromethyl ethyl ether | [CAS]
3188-13-4 | [Synonyms]
CHLOROMETHYL ETHYL ETHER
(chloromethoxy)-ethan
(chloromethoxy)ethane
1-(Chloromethoxy)ethane
Chloromethoxyethane
chloromethoxy-ethane
chloromethylethylester
ClCH2OC2H5
Ether, chloromethyl ethyl
Ethoxychloromethane
Ethoxymethyl chloride
ethoxymethylchloride
Ethyl chloromethyl ether
ethylchloromethylether
Chloromethyl ethyl ether, tech., stabilized, 80%
Chloromethyl ethyl ether, 80%, stabilized, tech. | [EINECS(EC#)]
221-687-5 | [Molecular Formula]
C3H7ClO | [MDL Number]
MFCD00000887 | [Molecular Weight]
94.54 | [MOL File]
3188-13-4.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR COLORLESS TO PALE YELLOW LIQUID | [Melting point ]
-104°C | [Boiling point ]
82 °C(lit.)
| [density ]
1.019 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.404(lit.)
| [Fp ]
67 °F
| [storage temp. ]
0-6°C | [solubility ]
Chloroform (Soluble), Ethyl Acetate (Slightly) | [form ]
Liquid | [color ]
Clear colorless to pale yellow | [Specific Gravity]
1.019 | [InChI]
InChI=1S/C3H7ClO/c1-2-5-3-4/h2-3H2,1H3 | [InChIKey]
FCYRSDMGOLYDHL-UHFFFAOYSA-N | [SMILES]
CCOCCl | [CAS DataBase Reference]
3188-13-4(CAS DataBase Reference) | [NIST Chemistry Reference]
Ethane, (chloromethoxy)-(3188-13-4) | [EPA Substance Registry System]
3188-13-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
F,Xn | [Risk Statements ]
R11:Highly Flammable.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36:Irritating to the eyes.
R40:Limited evidence of a carcinogenic effect. | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking .
S36/37:Wear suitable protective clothing and gloves .
S9:Keep container in a well-ventilated place .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S29:Do not empty into drains . | [RIDADR ]
UN 2354 3/PG 2
| [WGK Germany ]
3
| [HazardClass ]
6.1(a) | [PackingGroup ]
I | [HS Code ]
29091990 | [Hazardous Substances Data]
3188-13-4(Hazardous Substances Data) |
| Hazard Information | Back Directory | [General Description]
A colorless liquid. Slightly denser than water and insoluble in water. Flash point below 73°F. May be moderately toxic by ingestion, inhalation or skin absorption. Severely irritates skin, eyes and mucous membranes. | [Reactivity Profile]
CHLOROMETHYL ETHYL ETHER(3188-13-4) tends to form unstable peroxides when exposed to oxygen or air. These products can sometimes be observed as clear crystals deposited on containers or along the surface of the liquid. Forms salts with strong acids and addition complexes with Lewis acids. May react violently with strong oxidizing agents. I | [Air & Water Reactions]
Highly flammable. Insoluble in water. | [Health Hazard]
TOXIC; may be fatal if inhaled, ingested or absorbed through skin. Inhalation or contact with some of these materials will irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution. | [Fire Hazard]
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion and poison hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. | [Chemical Properties]
clear colorless to pale yellow liquid | [Uses]
Chloromethyl ethyl ether can be used to prepare:
- 6-Benzyl-1-(ethoxymethyl)-5-iodopyrimidine-2,4(1H,3H)-dione, a key intermediate in the preparation of MKC-442 analog.
- Acylation catalyst for alcohols named 1,3-bis-[(R)-1-(2-naphthyl)ethyl]imidazoliumchloride by reacting with glyoxal-bis-[(R)-1-(2-naphthyl)ethyl]imine.
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