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ChemicalBook CAS DataBase List Indan-2-amine
2975-41-9

Indan-2-amine synthesis

7synthesis methods
-

Yield:2975-41-9 93%

Reaction Conditions:

with palladium on activated charcoal;hydrogen;acetic acid;benzylamine in isopropyl alcohol at 80; under 22502.3 Torr;Autoclave;Solvent;Pressure;

Steps:

1-3 Example 3
In an autoclave, add 150g of 2-indanone, 145g of benzylamine, 600ml of isopropanol, and 8ml of glacial acetic acid. Add 20g of palladium-carbon catalyst, pass hydrogen to 3Mpa, and react at 80 ° C. After the reaction, press filter, concentrate the filtrate, and rectify 140 g of product were obtained, yield: 93%.

References:

Nanjing Huanran Biological Technology Co., Ltd.;Wang Kunpeng;Han Yuelin CN110229067, 2019, A Location in patent:Paragraph 0028-0033

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