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ChemicalBook CAS DataBase List 2-NITRO-1,3-INDANDIONE
3674-33-7

2-NITRO-1,3-INDANDIONE synthesis

7synthesis methods
-

Yield:-

Reaction Conditions:

in water;benzene;

Steps:

14.a Cyclisation of 2-methoxycarbonyl-ω-nitroacetophenone to 2-nitroindane-1,3-dione

a. A suspension of 2-methoxycarbonyl-ω-nitroacetophenone (2.23 g; 0.01 mole) in dry benzene (30 ml) was treated with sodium hydride (0.24 g; 0.01 mole) and the mixture heated for 6 hours at 100°C. After cooling, water was added and the phases separated. Acidification of the aqueous phase gave 0.964g of starting material. Evaporation of the aqueous filtrate gave a yellow solid which after recrystallisation gave 2-nitroindandione, m.p. (water: hydrochloric acid) 110°-113°C,

References:

US3983156,1976,A

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