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ChemicalBook CAS DataBase List Ethyl pivaloylacetate
17094-34-7

Ethyl pivaloylacetate synthesis

10synthesis methods
-

Yield:17094-34-7 91%

Reaction Conditions:

in paraffin oil;Diethyl carbonate

Steps:

1.4 Preparation of Pivaloyl Acetic Esters
4. 325 g of sodium hydride (80% solution in paraffin oil) were suspended in 2500 cc of diethyl carbonate and 500 cc of hexamethyl phosphoric acid triamide, 500 g of pinacolone (92%) were then slowly added dropwise at 45° to 50° C. and, on completion of the addition the reaction mixture was treated as described in 3 above. The yield was 91% of pivaloyl acetic acid ethyl ester.

References:

AGFA-Gevaert, A.G. US4031130, 1977, A

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