SALUBRINAL
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- $26 - $3443
- Product name: SALUBRINAL
- CAS: 405060-95-9
- MF: C21H17Cl3N4OS
- MW: 479.81
- EINECS:
- MDL Number:MFCD00548612
- Synonyms:(2E)-3-Phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-2-propenamide;2-Propenamide, 3-phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-, (2E)-;(2E)-3-Phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-2-propenamide Salubrinal;Salubrinal (2E)-3-Phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-2-propenamide;(E)-3-phenyl-N-[2,2,2-trichloro-1-(quinolin-8-ylcarbamothioylamino)ethyl]prop-2-enamide;N-(2,2,2-Trichloro-1-(3-(quinolin-8-yl)thioureido)ethyl)cinnAmamide;SALUBRINAL;SAL
38 prices
Selected condition：
Brand
- AK Scientific
- Alfa Aesar
- Ambeed
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 10
- 1mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product number2699AH
- Product descriptionSalubrinal
- Packaging5mg
- Price$151
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ64192
- Product descriptionSalubrinal
- Packaging5mg
- Price$121
- Updated2023-06-20
- Buy
- ManufacturerAlfa Aesar
- Product numberJ64192
- Product descriptionSalubrinal
- Packaging10mg
- Price$200
- Updated2023-06-20
- Buy
- ManufacturerAmbeed
- Product numberA591957
- Product descriptionSalubrinal 98+%
- Packaging5mg
- Price$256
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA591957
- Product descriptionSalubrinal 98+%
- Packaging25mg
- Price$431
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA591957
- Product descriptionSalubrinal 98+%
- Packaging100mg
- Price$727
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA591957
- Product descriptionSalubrinal 98+%
- Packaging1g
- Price$3443
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB2025
- Product descriptionSalubrinal
- Packaging10mg
- Price$105
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB2025
- Product descriptionSalubrinal
- Packaging10mM(in 1mL DMSO)
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB2025
- Product descriptionSalubrinal
- Packaging25mg
- Price$209
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60333
- Product descriptionSalubrinal
- Packaging10mg
- Price$238
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546223
- Product descriptionSalubrinal >98%
- Packaging5mg
- Price$209.1
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134482
- Product descriptionSalubrinal >99%
- Packaging100mg
- Price$510
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546223
- Product descriptionSalubrinal >98%
- Packaging25mg
- Price$513.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134482
- Product descriptionSalubrinal >99%
- Packaging250mg
- Price$765
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134482
- Product descriptionSalubrinal >99%
- Packaging1g
- Price$1504.5
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2699AH | Salubrinal | 5mg | $151 | 2021-12-16 | Buy |
| Alfa Aesar | J64192 | Salubrinal | 5mg | $121 | 2023-06-20 | Buy |
| Alfa Aesar | J64192 | Salubrinal | 10mg | $200 | 2023-06-20 | Buy |
| Ambeed | A591957 | Salubrinal 98+% | 5mg | $256 | 2021-12-16 | Buy |
| Ambeed | A591957 | Salubrinal 98+% | 25mg | $431 | 2021-12-16 | Buy |
| Ambeed | A591957 | Salubrinal 98+% | 100mg | $727 | 2021-12-16 | Buy |
| Ambeed | A591957 | Salubrinal 98+% | 1g | $3443 | 2021-12-16 | Buy |
| ApexBio Technology | B2025 | Salubrinal | 10mg | $105 | 2021-12-16 | Buy |
| ApexBio Technology | B2025 | Salubrinal | 10mM(in 1mL DMSO) | $180 | 2021-12-16 | Buy |
| ApexBio Technology | B2025 | Salubrinal | 25mg | $209 | 2021-12-16 | Buy |
| Arctom | CFN60333 | Salubrinal | 10mg | $238 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546223 | Salubrinal >98% | 5mg | $209.1 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb134482 | Salubrinal >99% | 100mg | $510 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546223 | Salubrinal >98% | 25mg | $513.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb134482 | Salubrinal >99% | 250mg | $765 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb134482 | Salubrinal >99% | 1g | $1504.5 | 2021-12-16 | Buy |
Properties
Melting point :>160°C (dec.)
Density :1.474±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :10.70±0.70(Predicted)
color :white to light yellow to light gray
Water Solubility :Insoluble in water.
Sensitive :Light Sensitive
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Density :1.474±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :10.70±0.70(Predicted)
color :white to light yellow to light gray
Water Solubility :Insoluble in water.
Sensitive :Light Sensitive
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Safety Information
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Description
Selective eukaryotic translation initiation factor 2 subunit α (elF2α) dephosphorylation inhibitor. Salubrinal is a selective Inhibitor of eIF2α (eukaryotic translation initiation factor 2 α-subunit) dephosphorylation, and is primarily used experimentally, to study stress responses in eukaryotic cells associated with the action of eIF2. Salubrinal indirectly inhibits eIF2 as a result of reduced dephosphorylation of its α-subunit resulting in activation of stress response pathways usually triggered by events such as oxidative stress or buildup of unfolded protein in the endoplasmic reticulum. Salubrinal can protect PC12 cells from endoplasmic reticulum stress-mediated apoptosis (EC50 = 15 μM) and prevent replication of herpes virus (IC50 = 3 μM), by inhibiting dephosphorylation of eIF2α. As eIF2α has a role in bone formation, salubrinal is also being studied for its effects in osteoporosis. Besides, it also shows potential neuroprotective actions. Although salubrinal has putative therapeutic value due to its function, it is as yet only used experimentally.More related product prices
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