Baricitinib
|
- $37 - $1802
- Product name: Baricitinib
- CAS: 1187594-09-7
- MF: C16H17N7O2S
- MW: 371.42
- EINECS:691-421-4
- MDL Number:MFCD21608464
- Synonyms:1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile;Baricitinib;INCB 028050;LY 3009104;BARICITINIB;INCB28050;LY3009104;Baricitinib (LY3009104);2-(3-(4-(3H-Pyrrolo[2,3-d]pyriMidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile;Baricitinib/INCB 028050/LY3009104
46 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Tocris
- TRC
Package
- 1mg
- 5mg
- 10mg
- 20mg
- 25mg
- 50mg
- 200mg
- 50
- 100mg
- 10mM(in 1mL DMSO)
- 250mg
- 500mg
- 1g
- 10g
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3734-M250
- Product descriptionBaricitinib ≥98%(HPLC)
- Packaging250mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY0439
- Product descriptionBaricitinib
- Packaging250mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY0439
- Product descriptionBaricitinib
- Packaging500mg
- Price$320
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4141
- Product descriptionBaricitinib(LY3009104,INCB028050)
- Packaging5mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4141
- Product descriptionBaricitinib(LY3009104,INCB028050)
- Packaging10mM(in 1mL DMSO)
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4141
- Product descriptionBaricitinib(LY3009104,INCB028050)
- Packaging10mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4141
- Product descriptionBaricitinib(LY3009104,INCB028050)
- Packaging50mg
- Price$520
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4141
- Product descriptionBaricitinib(LY3009104,INCB028050)
- Packaging200mg
- Price$1360
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0315
- Product descriptionBaricitinib
- Packaging5mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0315
- Product descriptionBaricitinib
- Packaging10mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0315
- Product descriptionBaricitinib
- Packaging50mg
- Price$264
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60434
- Product descriptionBaricitinib(INCB028050)
- Packaging20mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3630
- Product descriptionBaricitinib
- Packaging10mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3630
- Product descriptionBaricitinib
- Packaging100mg
- Price$79
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3630
- Product descriptionBaricitinib
- Packaging1g
- Price$229
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3630
- Product descriptionBaricitinib
- Packaging10g
- Price$1290
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-3734-M250 | Baricitinib ≥98%(HPLC) | 250mg | $120 | 2021-12-16 | Buy |
| AK Scientific | Y0439 | Baricitinib | 250mg | $218 | 2021-12-16 | Buy |
| AK Scientific | Y0439 | Baricitinib | 500mg | $320 | 2021-12-16 | Buy |
| ApexBio Technology | A4141 | Baricitinib(LY3009104,INCB028050) | 5mg | $120 | 2021-12-16 | Buy |
| ApexBio Technology | A4141 | Baricitinib(LY3009104,INCB028050) | 10mM(in 1mL DMSO) | $130 | 2021-12-16 | Buy |
| ApexBio Technology | A4141 | Baricitinib(LY3009104,INCB028050) | 10mg | $160 | 2021-12-16 | Buy |
| ApexBio Technology | A4141 | Baricitinib(LY3009104,INCB028050) | 50mg | $520 | 2021-12-16 | Buy |
| ApexBio Technology | A4141 | Baricitinib(LY3009104,INCB028050) | 200mg | $1360 | 2021-12-16 | Buy |
| Apolloscientific | BISN0315 | Baricitinib | 5mg | $68 | 2021-12-16 | Buy |
| Apolloscientific | BISN0315 | Baricitinib | 10mg | $108 | 2021-12-16 | Buy |
| Apolloscientific | BISN0315 | Baricitinib | 50mg | $264 | 2021-12-16 | Buy |
| Arctom | CFN60434 | Baricitinib(INCB028050) | 20mg | $218 | 2021-12-16 | Buy |
| AvaChem | 3630 | Baricitinib | 10mg | $39 | 2021-12-16 | Buy |
| AvaChem | 3630 | Baricitinib | 100mg | $79 | 2021-12-16 | Buy |
| AvaChem | 3630 | Baricitinib | 1g | $229 | 2021-12-16 | Buy |
| AvaChem | 3630 | Baricitinib | 10g | $1290 | 2021-12-16 | Buy |
Properties
Melting point :212-215°C
Density :1.56
storage temp. :-20°C
solubility :Soluble in DMSO (up to 30 mg/ml) or in DMF (up to 50 mg/ml).
pka :11.66±0.50(Predicted)
form :solid
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C16H17N7O2S/c1-2-26(24,25)22-9-16(10-22,4-5-17)23-8-12(7-21-23)14-13-3-6-18-15(13)20-11-19-14/h3,6-8,11H,2,4,9-10H2,1H3,(H,18,19,20)
InChIKey :XUZMWHLSFXCVMG-UHFFFAOYSA-N
SMILES :N1(S(CC)(=O)=O)CC(N2C=C(C3N=CN=C4NC=CC4=3)C=N2)(CC#N)C1
Density :1.56
storage temp. :-20°C
solubility :Soluble in DMSO (up to 30 mg/ml) or in DMF (up to 50 mg/ml).
pka :11.66±0.50(Predicted)
form :solid
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C16H17N7O2S/c1-2-26(24,25)22-9-16(10-22,4-5-17)23-8-12(7-21-23)14-13-3-6-18-15(13)20-11-19-14/h3,6-8,11H,2,4,9-10H2,1H3,(H,18,19,20)
InChIKey :XUZMWHLSFXCVMG-UHFFFAOYSA-N
SMILES :N1(S(CC)(=O)=O)CC(N2C=C(C3N=CN=C4NC=CC4=3)C=N2)(CC#N)C1
Safety Information
| Symbol(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
Janus kinases (JAKs) are non-receptor kinases that mediate signaling through cytokine receptors, often to members of the signal transducer and activator of transcription (Stat) family. Baricitinib is an orally bioavailable, reversible inhibitor of JAK1 and JAK2 (IC50s = 5.9 and 5.7 nM, respectively) that has been shown to inhibit cytokine-induced phosphorylation of STAT3 in healthy human volunteers. It has potential application in various inflammatory disorders, including rheumatoid arthritis.More related product prices
Ruxolitinib (1S,4Z,7S,10S,11E,20R)-4-ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3,6,18,21-tetrazabicyclo[8.7.6]tricos-11-ene-2,5,8,19,22-pentone 871700-17-3 Selumetinib 935666-88-9 Afatinib (BIBW 2992) Ibrutinib 1256580-46-7 Nintedanib Ethanesulfonate Salt AZD-9291 BIBW2992 DiMaleate Lapatinib ditosylate Regorafenib Unii-33Y9anm545 CabazitaxelRelated product price
Suppliers and manufacturers
TAIZHOU YUXIN BIOTECHNOLOGY CO,.LTD
AFINE CHEMICALS LIMITED
Changsha Junyu Chemexpress.co., Ltd
Beijing Hope Pharmaceutical Co., Ltd.
Shandong Hanjiang Chemical Co., Ltd
