(1S,4Z,7S,10S,11E,20R)-4-ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3,6,18,21-tetrazabicyclo[8.7.6]tricos-11-ene-2,5,8,19,22-pentone
![(1S,4Z,7S,10S,11E,20R)-4-ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3,6,18,21-tetrazabicyclo[8.7.6]tricos-11-ene-2,5,8,19,22-pentone price.](/CAS/GIF/128517-07-7.gif)
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- $28 - $4766.8
- Product name: (1S,4Z,7S,10S,11E,20R)-4-ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3,6,18,21-tetrazabicyclo[8.7.6]tricos-11-ene-2,5,8,19,22-pentone
- CAS: 128517-07-7
- MF: C24H36N4O6S2
- MW: 540.7
- EINECS:
- MDL Number:MFCD18433404
- Synonyms:FK228 RoMidepsin;5)-disulfide;Cyclo[(2Z)-2-aMino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-Mercapto-4-heptenoyl-D-valyl-D-cysteinyl],cyclic (3®(1S,4Z,7S,10S,11E,20R)-4-ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3,6,18,21-tetrazabicyclo[8.7.6]tricos-11-ene-2,5,8,19,22-pentone RoMidepsin (FK228, Depsipeptide);Romidepsin Antibiotic FR 901228;Romidepsin, >=98%;(1S,4Z,7S,10S,11E,20R)-4-ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3,6,18,21-tetrazabicyclo[;FR 901228
32 prices
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Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 500μg
- 1unit
- 1mg
- 1
- 2mg
- 5mg
- 10mM(in 1mL DMSO)
- 10mg
- 25mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberSYN5338
- Product descriptionRomidepsin
- Packaging10mg
- Price$628
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA380298
- Product descriptionRomidepsin 98+%
- Packaging1mg
- Price$243
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA380298
- Product descriptionRomidepsin 98+%
- Packaging5mg
- Price$243
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA380298
- Product descriptionRomidepsin 98+%
- Packaging10mg
- Price$942
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA380298
- Product descriptionRomidepsin 98+%
- Packaging100mg
- Price$1416
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA380298
- Product descriptionRomidepsin 98+%
- Packaging250mg
- Price$1416
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8173
- Product descriptionRomidepsin(FK228,depsipeptide)
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8173
- Product descriptionRomidepsin(FK228,depsipeptide)
- Packaging1mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8173
- Product descriptionRomidepsin(FK228,depsipeptide)
- Packaging5mg
- Price$330
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8173
- Product descriptionRomidepsin(FK228,depsipeptide)
- Packaging10mM(in 1mL DMSO)
- Price$390
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60009
- Product descriptionRomidepsin ≥98%
- Packaging5mg
- Price$463
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134739
- Product descriptionRomidepsin >99%
- Packaging100mg
- Price$1431.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134739
- Product descriptionRomidepsin >99%
- Packaging250mg
- Price$2395.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134739
- Product descriptionRomidepsin >99%
- Packaging1g
- Price$4766.8
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFR10656
- Product descriptionRomidepsin
- Packaging1mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFR10656
- Product descriptionRomidepsin
- Packaging2mg
- Price$125
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5338 | Romidepsin | 10mg | $628 | 2021-12-16 | Buy |
| Ambeed | A380298 | Romidepsin 98+% | 1mg | $243 | 2021-12-16 | Buy |
| Ambeed | A380298 | Romidepsin 98+% | 5mg | $243 | 2021-12-16 | Buy |
| Ambeed | A380298 | Romidepsin 98+% | 10mg | $942 | 2021-12-16 | Buy |
| Ambeed | A380298 | Romidepsin 98+% | 100mg | $1416 | 2021-12-16 | Buy |
| Ambeed | A380298 | Romidepsin 98+% | 250mg | $1416 | 2021-12-16 | Buy |
| ApexBio Technology | A8173 | Romidepsin(FK228,depsipeptide) | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A8173 | Romidepsin(FK228,depsipeptide) | 1mg | $110 | 2021-12-16 | Buy |
| ApexBio Technology | A8173 | Romidepsin(FK228,depsipeptide) | 5mg | $330 | 2021-12-16 | Buy |
| ApexBio Technology | A8173 | Romidepsin(FK228,depsipeptide) | 10mM(in 1mL DMSO) | $390 | 2021-12-16 | Buy |
| Arctom | CFN60009 | Romidepsin ≥98% | 5mg | $463 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb134739 | Romidepsin >99% | 100mg | $1431.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb134739 | Romidepsin >99% | 250mg | $2395.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb134739 | Romidepsin >99% | 1g | $4766.8 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FR10656 | Romidepsin | 1mg | $80 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FR10656 | Romidepsin | 2mg | $125 | 2021-12-16 | Buy |
Properties
Melting point :219-224°C
Boiling point :942.8±65.0 °C(Predicted)
Density :1.174
storage temp. :-20°C
solubility :Soluble in DMSO (up to 10 mg/ml).
pka :11.33±0.60(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Boiling point :942.8±65.0 °C(Predicted)
Density :1.174
storage temp. :-20°C
solubility :Soluble in DMSO (up to 10 mg/ml).
pka :11.33±0.60(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Safety Information
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| Signal word: | Danger | ||||||||||||||||||||||||||||||||||||||||
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Description
Romidepsin, also known as FK228, is a natural bicyclic depsipeptide that, following reduction, selectively inhibits class I histone deacetylases (HDACs). Reduction of a disulfide bond on romidepsin within the cell generates a zinc-binding thiol, allowing potent inhibition of HDACs 1, 2, 3, and 8 (IC50s = 53, 39, 53, and 26 nM, respectively), with less potency against HDACs 4, 6, 7, and 9 (IC50s = 470, 330, 3,200, and 12,000 nM, respectively). Through its effects on HDACs, romidepsin has anti-cancer activities, particularly against certain T cell lymphomas.More related product prices
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Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
Biochempartner
Hubei xin bonus chemical co. LTD
BOC Sciences
Chongqing Chemdad Co., Ltd
Shenzhen Excellent Biotech Co., Ltd.
Jurong Coupling Biotechnology Co., Ltd.
Antai Fine Chemical Technology Co.,Limited
![(1S,4Z,7S,10S,11E,20R)-4-ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3,6,18,21-tetrazabicyclo[8.7.6]tricos-11-ene-2,5,8,19,22-pentone](https://img.chemicalbook.com/ProductImageEN/2018-8/small/f4935d30-a38e-4bef-be96-57c345a031ed.jpg){kind=small}
