5-[3-Methoxy-4-(4-methoxy-benzyloxy)-benzyl]-pyrimidine-2,4-diamine
![5-[3-Methoxy-4-(4-methoxy-benzyloxy)-benzyl]-pyrimidine-2,4-diamine price.](/CAS2/GIF/870483-87-7.gif)
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- $8 - $3062.2
- Product name: 5-[3-Methoxy-4-(4-methoxy-benzyloxy)-benzyl]-pyrimidine-2,4-diamine
- CAS: 870483-87-7
- MF: C20H22N4O3
- MW: 366.41
- EINECS:
- MDL Number:MFCD12024701
- Synonyms:5-[3-Methoxy-4-(4-methoxy-benzyloxy)-benzyl]-pyrimidine-2,4-diamine;GW2580;SC-203877;SC-203877/GW2580;2,4-Pyrimidinediamine, 5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-;5-[[3-Methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-Pyrimidinediamine;5-[[3-Methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]pyrimidine-2,4-diamine;GW2580, >=98%
43 prices
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Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- 2g
- 10
- 50
- 5G
- ManufacturerAK Scientific
- Product numberY0454
- Product description5-(3-Methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine
- Packaging5mg
- Price$123
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA161762
- Product descriptionGW 2580 98+%
- Packaging1mg
- Price$8
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA161762
- Product descriptionGW 2580 98+%
- Packaging10mg
- Price$26
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA161762
- Product descriptionGW 2580 98+%
- Packaging100mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA161762
- Product descriptionGW 2580 98+%
- Packaging250mg
- Price$163
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA161762
- Product descriptionGW 2580 98+%
- Packaging1g
- Price$425
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000563
- Product description5-(3-METHOXY-4-(4-METHOXYBENZYLOXY)BENZYL)PYRIMIDINE-2,4-DIAMINE 95.00%
- Packaging1MG
- Price$140.7
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000563
- Product description5-(3-METHOXY-4-(4-METHOXYBENZYLOXY)BENZYL)PYRIMIDINE-2,4-DIAMINE 95.00%
- Packaging100MG
- Price$659.74
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000563
- Product description5-(3-METHOXY-4-(4-METHOXYBENZYLOXY)BENZYL)PYRIMIDINE-2,4-DIAMINE 95.00%
- Packaging1G
- Price$1267.33
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000563
- Product description5-(3-METHOXY-4-(4-METHOXYBENZYLOXY)BENZYL)PYRIMIDINE-2,4-DIAMINE 95.00%
- Packaging5G
- Price$3062.2
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1655
- Product descriptionGW 2580
- Packaging10mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1655
- Product descriptionGW 2580
- Packaging50mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1655
- Product descriptionGW 2580
- Packaging100mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545996
- Product descriptionGW 2580 >98%
- Packaging5mg
- Price$193.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545996
- Product descriptionGW 2580 >98%
- Packaging25mg
- Price$535.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154709
- Product descriptionGW-2580 (GW2580) >99%
- Packaging250mg
- Price$765
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | Y0454 | 5-(3-Methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine | 5mg | $123 | 2021-12-16 | Buy |
| Ambeed | A161762 | GW 2580 98+% | 1mg | $8 | 2021-12-16 | Buy |
| Ambeed | A161762 | GW 2580 98+% | 10mg | $26 | 2021-12-16 | Buy |
| Ambeed | A161762 | GW 2580 98+% | 100mg | $95 | 2021-12-16 | Buy |
| Ambeed | A161762 | GW 2580 98+% | 250mg | $163 | 2021-12-16 | Buy |
| Ambeed | A161762 | GW 2580 98+% | 1g | $425 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000563 | 5-(3-METHOXY-4-(4-METHOXYBENZYLOXY)BENZYL)PYRIMIDINE-2,4-DIAMINE 95.00% | 1MG | $140.7 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000563 | 5-(3-METHOXY-4-(4-METHOXYBENZYLOXY)BENZYL)PYRIMIDINE-2,4-DIAMINE 95.00% | 100MG | $659.74 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000563 | 5-(3-METHOXY-4-(4-METHOXYBENZYLOXY)BENZYL)PYRIMIDINE-2,4-DIAMINE 95.00% | 1G | $1267.33 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000563 | 5-(3-METHOXY-4-(4-METHOXYBENZYLOXY)BENZYL)PYRIMIDINE-2,4-DIAMINE 95.00% | 5G | $3062.2 | 2021-12-16 | Buy |
| ApexBio Technology | A1655 | GW 2580 | 10mg | $65 | 2021-12-16 | Buy |
| ApexBio Technology | A1655 | GW 2580 | 50mg | $75 | 2021-12-16 | Buy |
| ApexBio Technology | A1655 | GW 2580 | 100mg | $95 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545996 | GW 2580 >98% | 5mg | $193.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545996 | GW 2580 >98% | 25mg | $535.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb154709 | GW-2580 (GW2580) >99% | 250mg | $765 | 2021-12-16 | Buy |
Properties
Boiling point :617.5±65.0 °C(Predicted)
Density :1.252±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble10mg/mL, clear (warmed)
form :powder
pka :7.11±0.10(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Density :1.252±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble10mg/mL, clear (warmed)
form :powder
pka :7.11±0.10(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Safety Information
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Description
cFMS kinase is the cellular homolog of the v-FMS oncogene product of the Susan McDonough strain of the feline sarcoma virus. It can autophosphorlyate colony-stimulating factor (CSF-1), which promotes the survival, proliferation, and differentiation of mononuclear phagocytes. GW 2580 selectively inhibits cFMS kinase (IC50 = 0.03 μM), preventing CSF-1-induced monocyte growth with an IC50 value of 0.14 μM. At 75-100 mg/kg, it has been shown to inhibit joint connective tissue and bone degradation in mouse models of arthritis.Related product price
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