中文名:NG-單甲基-L-精氨酸乙酸鹽
英文名:NG-Monomethyl-L-arginine Acetate
中文別名:NG-甲基-L-精氨酸 乙酸鹽|Nω-甲基-L-精氨酸 乙酸鹽|NG-一甲基-L-精氨酸 乙酸鹽|N5-(甲基脒基)-L-鳥氨酸 乙酸鹽|L-NMMA 一乙酸酯|N5-[亞氨基(甲基氨基)甲基]-L-鳥氨酸單乙酸鹽
英文別名:L-NMMA acetate|Tilarginine Acetate|53308-83-1|L-NMMA|NG-Monomethyl-L-arginine acetate|NG-Methyl-L-arginine acetate salt|Targinine acetate|Tilarginine acetate [USAN]|L-NMMA (acetate)|ANO-1020|Ng-methylarginine acetate|N-Omega-monomethyl-L-arginine acetate|
純度:10mM in Water
貨號(hào):N424563
包裝:1ml
Cas號(hào):53308-83-1
存儲(chǔ)溫度:-80℃儲(chǔ)存
產(chǎn)品介紹:
L-NG-Monomethylarginine, Acetate Salt (L-NMMA), is an analogue of L-arginine that has been shown to inhibit Ca2+-dependent NOS3 (endothelial NOS) from porcine aorta. In an experiment on porcine aortic rings, L-NMMA was shown to cause contraction and inhibition of the endothelium-dependent relaxation induced by acetylcholine. This compound has also been noted to elicit a dose-dependent increase in mean systemic arterial blood pressure accompanied by bradycardia. Experiments on cat vascular endothelia show that L-NMMA can increase leukocyte adherence and emigration and reduce venular shear rate. Low shear rates have been shown to promote platelet-endothelial and leukocyte-endothelial cell adhesion in mesenteric venules. L-NG-Monomethylarginine, Acetate Salt (L-NMMA) is an inhibitor of NOS1 and NOS2.
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