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ChemicalBook >> CAS DataBase List >> Entecavir hydrate

Entecavir hydrate

Entecavir hydrate price.
  • $16 - $6000
  • Product name: Entecavir hydrate
  • CAS: 209216-23-9
  • MF: C12H17N5O4
  • MW: 295.3
  • EINECS:606-668-5
  • MDL Number:MFCD09754448
  • Synonyms:entecavir hydrate;ENTECAVIR MONOHYDRATE;2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate;Entecavir hydrate / 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate;2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate ,99.9%;2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate ,99.7%;Entecavir Monohydrate IsoMers;2-aMino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxyMethyl)-2-Methylidenecyclopentyl]-6,9-dihydro-3H-purin-6-one
49 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Usbiological
Package
  • 10mM(in 1mL DMSO)
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200MG
  • 250mg
  • 1g
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-E0229-M050
  • Product descriptionEntecavir Monohydrate ≥98%(HPLC)
  • Packaging50mg
  • Price$82
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberP238
  • Product descriptionEntecavir Monohydrate
  • Packaging1g
  • Price$541
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA148639
  • Product descriptionEntecavir Monohydrate 98+%
  • Packaging1g
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA148639
  • Product descriptionEntecavir Monohydrate 98+%
  • Packaging250mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA148639
  • Product descriptionEntecavir Monohydrate 98+%
  • Packaging100mg
  • Price$37
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA148639
  • Product descriptionEntecavir Monohydrate 98+%
  • Packaging50mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA148639
  • Product descriptionEntecavir Monohydrate 98+%
  • Packaging10mg
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA148639
  • Product descriptionEntecavir Monohydrate 98+%
  • Packaging5mg
  • Price$16
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0024618
  • Product descriptionENTECAVIR HYDRATE 95.00%
  • Packaging250MG
  • Price$1800
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0024618
  • Product descriptionENTECAVIR HYDRATE 95.00%
  • Packaging1G
  • Price$6000
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1767
  • Product descriptionEntecavirHydrate
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1767
  • Product descriptionEntecavirHydrate
  • Packaging5mg
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1767
  • Product descriptionEntecavirHydrate
  • Packaging25mg
  • Price$195
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1767
  • Product descriptionEntecavirHydrate
  • Packaging100mg
  • Price$319
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS047031
  • Product descriptionEntecavir Monohydrate ≥98%
  • Packaging5mg
  • Price$16
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS047031
  • Product descriptionEntecavir Monohydrate ≥98%
  • Packaging10mg
  • Price$20
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-E0229-M050 Entecavir Monohydrate ≥98%(HPLC) 50mg $82 2021-12-16 Buy
AK Scientific P238 Entecavir Monohydrate 1g $541 2021-12-16 Buy
Ambeed A148639 Entecavir Monohydrate 98+% 1g $190 2021-12-16 Buy
Ambeed A148639 Entecavir Monohydrate 98+% 250mg $55 2021-12-16 Buy
Ambeed A148639 Entecavir Monohydrate 98+% 100mg $37 2021-12-16 Buy
Ambeed A148639 Entecavir Monohydrate 98+% 50mg $30 2021-12-16 Buy
Ambeed A148639 Entecavir Monohydrate 98+% 10mg $20 2021-12-16 Buy
Ambeed A148639 Entecavir Monohydrate 98+% 5mg $16 2021-12-16 Buy
American Custom Chemicals Corporation API0024618 ENTECAVIR HYDRATE 95.00% 250MG $1800 2021-12-16 Buy
American Custom Chemicals Corporation API0024618 ENTECAVIR HYDRATE 95.00% 1G $6000 2021-12-16 Buy
ApexBio Technology A1767 EntecavirHydrate 10mM(in 1mL DMSO) $55 2021-12-16 Buy
ApexBio Technology A1767 EntecavirHydrate 5mg $68 2021-12-16 Buy
ApexBio Technology A1767 EntecavirHydrate 25mg $195 2021-12-16 Buy
ApexBio Technology A1767 EntecavirHydrate 100mg $319 2021-12-16 Buy
Arctom AS047031 Entecavir Monohydrate ≥98% 5mg $16 2021-12-16 Buy
Arctom AS047031 Entecavir Monohydrate ≥98% 10mg $20 2021-12-16 Buy

Properties

Melting point :>220°
alpha :D +35.0° (c = 0.38 in water)
Density :1.81
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO (Slightly), Methanol (Sparingly), Water (Slightly, Heated, Sonicated)
form :Solid
color :White to Off-White
Merck :14,3595
InChI :InChI=1/C12H15N5O3.H2O/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20;/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20);1H2/t6-,7-,8-;/s3
InChIKey :YXPVEXCTPGULBZ-UQHDSAJHNA-N
SMILES :C=C1[C@@H]([C@@H](O)C[C@@H]1N1C=NC2C(NC(N)=NC1=2)=O)CO.O |&1:2,3,6,r|
CAS DataBase Reference :209216-23-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Entecavir is a potent deoxyguanosine nucleoside analog with antiviral activity selective for hepadnaviruses (EC50 = 3.7 nM against the hepatitis B virus (HBV) in cultured 2.2.15 liver cells). In vitro, the active intracellular form of entecavir, entecavir triphosphate, demonstrates a higher binding affinity for HBV DNA polymerase than the natural guanosine triphosphate substrate and effectively inhibits HBV DNA replication at 3 stages in the replication pathway: priming, reverse transcription, and DNA-dependent DNA synthesis. The potential therapeutic bene?ts of entecavir have been demonstrated in woodchuck and duck models of HBV. Activity was con?rmed in phase I/II preclinical studies and entecavir received approval from the U.S. Food and Drug Administration for the treatment of adults with chronic hepatitis B.

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