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  P238    
Entecavir monohydrate
, 98% (HPLC)
 
Baraclude




IDENTITY
CAS Number:209216-23-9
MDL Number:MFCD09754448
MF:C12H15N5O3.H2O
MW:295.29
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:>220°C
Optical Rotation:+10.8° (c=20mg/10ml of MeOH)
Long-Term Storage:Store long-term at 2-8°C
Note:Loss on drying max 5%
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 59mg/mL; H2O: insoluble; EtOH: <1mg/mL
Application(s):Antiviral; Viral DNA Polymerase Inhibitor
Form:Hydrate

REVIEW

 Entecavir hydrate is an oral antiviral drug used in the treatment of hepatitis B infection. Entecavir hydrate is a nucleoside analog (more specifically, a guanine analogue) that inhibits reverse transcription, DNA replication and transcription in the viral replication process.

REFERENCES
[1]Wong GL, Wong VW, Chan HY, Tse PC, Wong J, Chim AM, Yiu KK, Chu SH, Chan HL (2012). Undetectable HBV DNA at month 12 of entecavir treatment predicts maintained viral suppression and HBeAg-seroconversion in chronic hepatitis B patients at 3 years. Aliment Pharmacol Ther. 35(11):1326-35. PMID 22506552.
[2] 'Pol S, Lampertico P (2012). First-line treatment of chronic hepatitis B with entecavir or tenofovir in ''real-life'' settings: from clinical trials to clinical practice. J Viral Hepat. 19(6):377-86. PMID 22571899. '

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302

Precautionary Statements
P270; P264; P301+P312+P330; P330; P501;


RELATED PRODUCTS
G985Entecavir
P238Entecavir monohydrate

Current as of November 8, 2024


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All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.



CATEGORIES

 APIs and Bioactives > Antivirals;NRTIs


PubChem
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