Fmoc-L-glutamic acid 5-tert-butyl ester
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Fmoc-L-glutamic acid 5-tert-butyl ester ??
- ???
- 83-90 °C
- ??
- -4.5 º (c=1, 80% acetic acid)
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- 633.5±55.0 °C(Predicted)
- ??
- 1.232±0.06 g/cm3(Predicted)
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- -4 ° (C=1, 80% AcOH)
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- Store below +30°C.
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- powder to crystal
- ?? ?? (pKa)
- 3.70±0.10(Predicted)
- ??
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- optical activity
- [α]20/D 5.0±2.0°, c = 1% in acetic acid: water (4:1)
- BRN
- 3636375
- InChIKey
- OTKXCALUHMPIGM-FQEVSTJZSA-N
- SMILES
- C(O)(=O)[C@H](CCC(OC(C)(C)C)=O)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
- CAS ??????
- 71989-18-9(CAS DataBase Reference)
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- ?? ? ???? ?? (GHS)
??? ?? | Xi | ||
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?? ???? ?? | 36/37/38 | ||
????? | 26-27-36/37/39-24/25 | ||
WGK ?? | 3 | ||
HS ?? | 2924 29 70 |
Fmoc-L-glutamic acid 5-tert-butyl ester C??? ??, ??, ??
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Fmoc-L-glutamic acid 5-tert-butyl ester is a Fmoc derivative with an N-substituted tert-butyl ester molecule. It is white or gray-white solid crystals at room temperature and pressure, poor solubility in water and insoluble in petroleum ether, but soluble in ethyl acetate, acetic acid and N,N-dimethylformamide.??? ??
White powder??
Fmoc-Glu(OtBu)-OH (Fmoc-L-glutamic acid 5-tert-butyl ester) can be employed as a:- Ligand in the synthesis of cis-substituted cyclopropane carboxylic acids via C-H activation of cyclopropane carboxamides using Pd catalyst.
- Linker in the preparation of multi-small molecule-conjugated PTX (paclitaxel) derivatives.
It can be also used as a building block in the preparation of stapled α-helical peptides , and peptide C-terminal thioesters .
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The product number for this product was previously 04-12-1020.To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
Fmoc-L-glutamic acid 5-tert-butyl ester ?? ?? ? ???
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Fmoc-L-glutamic acid 5-tert-butyl ester ?? ??
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