4-Amino-7H-pyrrolo[2,3-d]pyrimidine
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- CAS-Nr.
- 1500-85-2
- Englisch Name:
- 4-Amino-7H-pyrrolo[2,3-d]pyrimidine
- Synonyma:
- 7-DEAZAADENINE;6-Amino-7-deazapurine;6-AMino-7-deazapurine 97%;4-Amino-7H-pyrrolo[2,3-d]...;4-Aminopyrrolo[2,3-d]Pyrimidin;4-AMINOPYRROLO[2,3-D]PYRIMIDINE;1H-Pyrrolo[2,3-d]pyrimidin-4-amin;7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE;3-d)pyrimidine,4-amino-7h-pyrrolo(;4-Amino-7H-pyrrolo[2,3-d]pyrimidine
- CBNumber:
- CB6306218
- Summenformel:
- C6H6N4
- Molgewicht:
- 134.14
- MOL-Datei:
- 1500-85-2.mol
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4-Amino-7H-pyrrolo[2,3-d]pyrimidine Eigenschaften
- Schmelzpunkt:
- 257-262℃
- Siedepunkt:
- 318.3±45.0 °C(Predicted)
- Dichte
- 1.61±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 13.38±0.20(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to pale brown
- Sensitive
- Moisture & Light Sensitive
- InChIKey
- PEHVGBZKEYRQSX-UHFFFAOYSA-N
- CAS Datenbank
- 1500-85-2(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
T |
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| R-S?tze: |
25 |
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| S-S?tze: |
45 |
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| RIDADR |
UN 2811 6.1/PG 1 |
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| WGK Germany |
2 |
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| RTECS-Nr. |
UY8850000 |
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| HazardClass |
IRRITANT |
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| PackingGroup |
Ⅲ |
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| HS Code |
2933599590 |
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| Toxizit?t |
mouse,LD50,intraperitoneal,300mg/kg (300mg/kg),Gann. Japanese Journal of Cancer Research. Vol. 56, Pg. 219, 1965. |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 3 |
Achtung |
![GHS hazard pictograms]() src="/GHS06.jpg" width="20" height="20" /> |
P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
| P301+P310 |
BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
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4-Amino-7H-pyrrolo[2,3-d]pyrimidine Chemische Eigenschaften,Einsatz,Produktion Methoden
Synthese
A mixture of 5-ethynylpyrimidine-4,6-diamine (300?mg, 2.24?mmol), Cs2CO3 (1.46?g, 4.47?mmol) and DMSO (4.00?ml) in a 10.00?ml microwave tube was irradiated at 100?W and 180?°C for 15?minutes. After this time, the reaction mixture was cooled to room temperature and poured into a separating funnel containing 100?ml water and 100?ml ethyl acetate. The aqueous layer was extracted with EtOAc (2×100?ml). The combined organic extracts were dried with MgSO4 and filtered through celite, and excess solvent was removed in vacuo. Purification by column chromatography (80?% EtOAc/hexane – 10?% MeOH/CH2Cl2) gave 7H-pyrrolo[2,3-d]pyrimidin-4-amine (4-Amino-7H-pyrrolo[2,3-d]pyrimidine) (0.15?g, 50?%) as an off-white solid[1].
4-Amino-7H-pyrrolo[2,3-d]pyrimidine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-Amino-7H-pyrrolo[2,3-d]pyrimidine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 221)Lieferanten
1500-85-2()Verwandte Suche:
- 6-AMino-7-deazapurine 97%
- 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 6-Amino-7-deazapurine
- 7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE
- 7-DEAZAADENINE
- 4-AMINOPYRROLO[2,3-D]PYRIMIDINE
- 4-Amino-7H-pyrrolo[2,3-d]pyrimidine
- 3-d)pyrimidine,4-amino-7h-pyrrolo(
- 6-Amino-7-deazapurine
- 1H-Pyrrolo[2,3-d]pyrimidin-4-amine (9CI)
- 4-Aminopyrrolo[2,3-d]Pyrimidin
- 4-AMINO-7H-PYRROLO[2,3-D]PYRIMIDINE SULFATE 98%
- 7H-Pyrrolo[2,3-D]pyrimidin-4-ylamine
- 4-Amino-7H-pyrrolo[2,3-d]...
- 4-Amino-7H-pyrrolo[2,3-d]pyrimidine ISO 9001：2015 REACH
- 1H-Pyrrolo[2,3-d]pyrimidin-4-amin
- 1500-85-2
- 856600-01-2
- Heterocycle-Pyrimidine series
- Building Blocks
- Chemical Synthesis
- Heterocyclic Building Blocks
- Purines
- Heterocycles series
- Amines
- Fused Ring Systems
- PYRIMIDINE
