7-beta-D-Ribofuranosyl-7H-pyrrolo-(2,3-d)pyrimidin-4-amin
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- CAS-Nr.
- 69-33-0
- Bezeichnung:
- 7-beta-D-Ribofuranosyl-7H-pyrrolo-(2,3-d)pyrimidin-4-amin
- Englisch Name:
- TUBERCIDIN
- Synonyma:
- (2R,3R,4S,5R)-2-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol;b120121;u-10071;CS-2599;nsc56408;ski26996;Aids051983;TUBERCIDIN;7-Deaza-Ar;7-Deaza-rA
- CBNumber:
- CB0461137
- Summenformel:
- C11H14N4O4
- Molgewicht:
- 266.25
- MOL-Datei:
- 69-33-0.mol
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7-beta-D-Ribofuranosyl-7H-pyrrolo-(2,3-d)pyrimidin-4-amin Eigenschaften
- Schmelzpunkt:
- 247-248 °C (decomp)(Solv: water (7732-18-5))
- alpha
- D17 -67° (50% acetic acid)
- Siedepunkt:
- 409.46°C (rough estimate)
- Dichte
- 1.2896 (rough estimate)
- Brechungsindex
- 1.8340 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- L?slichkeit
- Soluble in DMSO
- Aggregatzustand
- powder
- pka
- 12.44±0.70(Predicted)
- Farbe
- off-white
- Merck
- 13,9875
- BRN
- 38498
- Stabilit?t:
- Hygroscopic
- InChIKey
- HDZZVAMISRMYHH-UIRWVKCDSA-N
- CAS Datenbank
- 69-33-0
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
T+ |
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| R-S?tze: |
28 |
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| S-S?tze: |
36/37/39-45 |
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| RIDADR |
UN 3462 6.1/PG 2 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
UY8870000 |
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| F |
10 |
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| HazardClass |
6.1(a) |
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| PackingGroup |
II |
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| HS Code |
29419090 |
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| Toxizit?t |
LD50 i.v. in mice: 45 mg/kg (Anzai) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H300 |
Lebensgefahr bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 2 |
Achtung |
![GHS hazard pictograms]() src="/GHS06.jpg" width="20" height="20" /> |
P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P301+P310 |
BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
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7-beta-D-Ribofuranosyl-7H-pyrrolo-(2,3-d)pyrimidin-4-amin Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R28:Sehr giftig beim Verschlucken.
S-S?tze Betriebsanweisung:
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
Chemische Eigenschaften
White crystal
Verwenden
Tubercidin is a nucleoside metabolite first isolated from Streptomyces tubericidus. Tubercidin, like other nucleosides, is a broad spectrum, potent chemotherapeutic agent active against viruses, bacteria, fungi, protozoans and tumours. Tubercidin acts at a diverse range of sites, such as RNA processing, nucleic acid and protein synthesis, and acts as a nucleoside mimic of adenosine.
Definition
ChEBI: An N-glycosylpyrrolopyrimidine that is adenosine in which the in the 5-membered ring that is not attached to the ribose moiety is replaced by a carbon. Tubercidin is produced in the culture broth of Streptomyces tubericidus.
l?uterung methode
7-Deazaadenosine forms needles from hot H2O. It is soluble in H2O (0.33%), MeOH (0.5%) and EtOH (0.05%). It has UV max at 270nm ( 12,100) in 0.001N NaOH. The picrate has m 229-231o(dec). [Tolman et al. J Am Chem Soc 91 2102 1969, Mizuno et al. J Org Chem 28 3329 1963, IR: Anzai et al. J Antibiot (Japan) [9] 10 201 1957, Beilstein 26 IV 1117.]
7-beta-D-Ribofuranosyl-7H-pyrrolo-(2,3-d)pyrimidin-4-amin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
7-beta-D-Ribofuranosyl-7H-pyrrolo-(2,3-d)pyrimidin-4-amin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 165)Lieferanten
69-33-0(7-beta-D-Ribofuranosyl-7H-pyrrolo-(2,3-d)pyrimidin-4-amin)Verwandte Suche:
- TUBERCIDINE
- 3-d)pyrimidin-4-amine,7-beta-d-ribofuranosyl-7h-pyrrolo(
- 3-d)pyrimidine,4-amino-7-beta-d-ribofuranosyl-7h-pyrrolo(
- 4-amino-7-(beta-d-ribofuranosyl)-pyrrolo(2,3-d)pyrimidine
- 4-amino-7-beta-d-ribofuranosyl-7h-pyrrolo(2,3-d)pyrimidine
- 7-beta-d-ribofuranosyl-7h-pyrrolo(2,3-d)pyrimidine-4-amine
- 7-deaza-adenosin
- antibiotic155b2t
- antibioticxk101-1
- b120121
- nsc56408
- 7-Deazaadenosine, XK 101-1, NSC 56408, SparsoMycin A, U 10071
- Sparsamycin A
- N7-Deazaadenosine
- 7H-Pyrrolo[2,3-d]pyrimidin-4-amine,7-b-D-ribofuranosyl-
- ski26996
- sparsomycina
- u-10071
- tubercidin from streptomyces tubercidicus
- tubercidin from streptomyces*tubercidicus
- 7-beta-CD-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- 4-AMINO-7-BETA-D-RIBOFURANOSYL-7H-PYROLLO(2,3-D)PYRIMIDINE
- 7H-Pyrrolo2,3-dpyrimidin-4-amine, 7-.beta.-D-ribofuranosyl-
- 7-Deaza-D-adenosine
- 4-Amino-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine
- Sparsomycine A
- 7-.beta.-D-ribofuranosyl-7H-pyrrolo-[2,3-d]pyrimidin-4-amine
- 7-Deazadenosine
- 7H-Pyrrolo(2,3-D)pyrimidine, 4-amino-7-beta-D-ribofuranosyl-
- Aids051983
- Aids-051983
- 2-(4-aMinopyrrolo[2,3-d]pyriMidin-7-yl)-5-(hydroxyMethyl)oxolane-3,4-diol
- 7-deaza-adenosin(Tubercidine)
- 7-DEAZAADENOSINE
- TUBERCIDIN
- Tubercidin (7-Deazaadenosine
- 7-Deaza-adeonsine
- CS-2599
- Tubercidin, >97%
- 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-β-D-ribofuranosyl-
- 7-Deazaadenosine, Tubercidin, Sparsomycine A
- 4-Amino-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine
- TUBERCIDIN USP/EP/BP
- 7-Deaza-Ar
- (2R,3R,4S,5R)-2-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
- 7-Deaza-rA
- Tubercidin (6CI)
- 4-Amino-7-(b-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine
- Tubercidin, 10 mM in DMSO
- 69-33-0
- Antibiotics T-Z
- Antibiotics
- Antibiotics A to Z
- BioChemical
