Desoxycortonacetat
|
|
|
- CAS-Nr.
- 56-47-3
- Bezeichnung:
- Desoxycortonacetat
- Englisch Name:
- Deoxycorticosterone acetate
- Synonyma:
- doxo;DOCA;steraq;arcort;ocriten;syncort;cortate;percotol;syncorta;unidocan
- CBNumber:
- CB3462948
- Summenformel:
- C23H32O4
- Molgewicht:
- 372.5
- MOL-Datei:
- 56-47-3.mol
|
Desoxycortonacetat Eigenschaften
- Schmelzpunkt:
- 157°C
- alpha
- D20 +168 to +176° (dioxane)
- Siedepunkt:
- 421.94°C (rough estimate)
- Dichte
- 1.0415 (rough estimate)
- Brechungsindex
- 175 ° (C=1, Dioxane)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- H2O: insoluble
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Wasserl?slichkeit
- 4mg/L(25 ºC)
- Merck
- 2901
- BRN
- 2570798
- InChI
- InChI=1S/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17-,18-,19-,20+,22-,23-/m0/s1
- InChIKey
- VPGRYOFKCNULNK-ACXQXYJUSA-N
- SMILES
- C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@H](C(=O)COC(C)=O)CC3)CC2
- LogP
- 3.080
- CAS Datenbank
- 56-47-3(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| S-S?tze: |
22-24/25 |
|
|
| RIDADR |
UN 2811 |
|
|
| WGK Germany |
3 |
|
|
| RTECS-Nr. |
HG0525000 |
|
|
| HazardClass |
IRRITANT |
|
|
| HS Code |
2937290000 |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H360 |
Kann die Fruchtbarkeit beeintr?chtigen oder das Kind im Mutterleib sch?digen. |
Fertility (Fruchtbarkeit) |
Kategorie 1 |
Achtung |
![GHS hazard pictograms]() src="/GHS08.jpg" width="20" height="20" /> |
|
| H373 |
Kann die Organe sch?digen bei l?ngerer oder wiederholter Exposition. |
Spezifische Zielorgan-Toxizit?t (wiederholte Exposition) |
Kategorie 2 |
Warnung |
|
P260, P314, P501 |
|
| Sicherheit |
| P260 |
Dampf/Aerosol/Nebel nicht einatmen. |
| P314 |
Bei Unwohlsein ?rztlichen Rat einholen / ?rztliche Hilfe hinzuziehen. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
|
Desoxycortonacetat Chemische Eigenschaften,Einsatz,Produktion Methoden
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
Off-White Solid
Verwenden
Deoxycorticosterone acetate has been used to induce hypertensive pregnancy. It has also been used to investigate the effect of low epicatechin dosing on the cardiovascular function of deoxycorticosterone acetate (DOCA)-salt hypertensive rats.
Allgemeine Beschreibung
Deoxycorticosterone acetate is an endogenous neurosteroid found in brain and peripheral circulation, which is produced by progesterone. It is both a mineralocorticoid and a glucocorticoid. It is used to treat adrenocortical insufficiency or Addison′s disease. Deoxycorticosterone acetate improves insulin sensitivity. It acts as a precursor to glucocorticoid corticosterone and the GABAergic neuroactive steroid (3α,5α)-3,21-dihydroxypregnan-20-one.
l?uterung methode
11-Deoxycorticosterone acetate recrystallises from EtOH as needles or Me2CO/hexane, and sublimes at high vacuum. It is partly soluble in MeOH, Me2CO, Et2O and dioxane but insoluble in H2O. [Reichstein & Euw Helv Chim Acta 23 136 1940, Romo et al. J Am Chem Soc 79 5034 1957; NMR: Shoolery & Rogers J Am Chem Soc 80 5121 1959, Beilstein 8 IV 2195.]
Desoxycortonacetat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Desoxycortonacetat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 260)Lieferanten
56-47-3(Desoxycortonacetat)Verwandte Suche:
- deoxycortoneacetate
- descorterone
- descotone
- desoxycorticosterone-21-acetate
- dorcostrin
- doxo
- doxycamon
- krinocorts
- ocriten
- organon’sdocaacetate
- percorten
- percotol
- Pregn-4-en-21-ol-3,20-dione21-acetate
- primocort
- primocortan
- sincortex
- steraq
- syncort
- syncorta
- syncortyl
- 4-pregnene-3,20-dione-21-olacetate
- unidocan
- 11-deoxycorticosterone21-acetate
- 20-dione,21-hydroxy-pregn-4-ene-acetate
- 21-acetoxy-3,20-diketopregn-4-ene
- 21-Acetyloxypregn-4-ene-3,20-dione
- 21-hydroxypregn-4-ene-3,20-dione21-acetate
- 11-DEOXYCORTICOSTERONE ACETATE
- 11-desoxycorticosterone acetate
- 21-ACETOXYPROGESTERONE
- 21-ACETOXY-4-PREGNENE-3,20-DIONE
- 21-HYDROXY-4-PREGNENE-3,20-DIONE 21-ACETATE
- 21-HYDROXYPROGESTERONE 21-ACETATE
- 21-HYDROXYPROGESTERONE ACETATE
- DESOXYCORTONE ACETATE
- DESOXYCORTICOSTERONE ACETATE
- DEOXYCORTICOSTERONE ACETATE
- DELTA4-PREGNEN-21-OL-3, 20-DIONE ACETATE
- CORTEXONE ACETATE
- DOCA
- DOC ACETATE
- 4-PREGNEN-21-OL-3,20-DIONE ACETATE
- 4-PREGNEN-21-OL-3,20-DIONE 21-ACETATE
- Desoxycorticostisone acetate
- 21-HYDROXYPROGESTERONE 21-ACETATE VETRAN
- 11-Deoxycorticosterone acetate, 21-Acetoxy-4-pregnene-3,20-dione, 21-Acetoxyprogesterone, 21-Hydroxy-4-pregnene-3,20-dione 21-acetate, 21-Hydroxyprogesterone 21-acetate, 4-Pregnen-21-ol-3,20-dione 21-acetate, Cortexone acetate, DOC acetate
- 21-Acetoxypregn-4-en-3,20-dione
- 21-Hydroxypregn-4-ene-3,20-dione Acetate
- Decorten
- Decosteron
- DEOXYCORTICOSTERONE ACETATE(RG)
- Desoxycorticosterone Acetate (200 mg)
- 3,20-Dioxopregn-4-en-21-yl acetate
- Pregn-4-ene-3,20-dione, 21-(acetyloxy)-
- DOCA(Deoxycorticosterone acetate)
- arcort
- bio-corten
- cortacet
