9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-valerat
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- CAS-Nr.
- 2152-44-5
- Bezeichnung:
- 9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-valerat
- Englisch Name:
- Betamethasone 17-valerate
- Synonyma:
- BETAMETHASONE VALERATE;VALISONE;Betaderm;BETNOVATE;BETHAMETASONE VALERATE;Luxiq;Betoid;Valison;9α-Fluo;Deviphos
- CBNumber:
- CB1317879
- Summenformel:
- C27H37FO6
- Molgewicht:
- 476.58
- MOL-Datei:
- 2152-44-5.mol
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9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-valerat Eigenschaften
- Schmelzpunkt:
- 183-184°
- alpha
- D +77° (dioxane)
- Siedepunkt:
- 598.9±50.0 °C(Predicted)
- Dichte
- 1.1174 (estimate)
- storage temp.
- 2-8°C
- L?slichkeit
- Practically insoluble in water, freely soluble in acetone and in methylene chloride, soluble in ethanol (96 per cent).
- Aggregatzustand
- Solid
- pka
- 12.90±0.70(Predicted)
- Farbe
- White
- Merck
- 13,1183
- BRN
- 4240001
- InChIKey
- SNHRLVCMMWUAJD-SUYDQAKGSA-N
- SMILES
- [C@]12(C)C[C@@H]([C@]3(F)[C@@]4(C)C=CC(=O)C=C4CC[C@@]3([H])[C@]1([H])C[C@H](C)[C@@]2(C(=O)CO)OC(=O)CCCC)O |&1:0,3,4,6,16,18,21,23,r|
- CAS Datenbank
- 2152-44-5(CAS DataBase Reference)
- EPA chemische Informationen
- .beta.-Methasone 17-valerate (2152-44-5)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
48 |
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| S-S?tze: |
22-24/25 |
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| RTECS-Nr. |
TU3835000 |
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| HS Code |
2937229000 |
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| Toxizit?t |
mouse,LD50,intraperitoneal,632mg/kg (632mg/kg),Shikoku Igaku Zasshi. Shikoku Medical Journal. Vol. 29, Pg. 153, 1973. |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H373 |
Kann die Organe sch?digen bei l?ngerer oder wiederholter Exposition. |
Spezifische Zielorgan-Toxizit?t (wiederholte Exposition) |
Kategorie 2 |
Warnung |
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P260, P314, P501 |
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| Sicherheit |
| P201 |
Vor Gebrauch besondere Anweisungen einholen. |
| P202 |
Vor Gebrauch alle Sicherheitshinweise lesen und verstehen. |
| P260 |
Dampf/Aerosol/Nebel nicht einatmen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P308+P313 |
BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
| P405 |
Unter Verschluss aufbewahren. |
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9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-valerat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R48:Gefahr ernster Gesundheitssch?den bei l?ngerer Exposition.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
White Solid
Definition
ChEBI: Betamethasone valerate is a steroid ester that is betamethasone in which the hydroxy group at the 17alpha position has been converted to the corresponding pentanoate ester. It has a role as an anti-inflammatory drug. It is a steroid ester, a 20-oxo steroid, a 21-hydroxy steroid, an 11beta-hydroxy steroid, a fluorinated steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a primary alpha-hydroxy ketone. It is functionally related to a betamethasone.
Indications
Betamethasone valerate (Psorion, Beta-Val, Luxiq) is a synthetic fluorinated corticosteroid.
Nebenwirkungen
Common side effects. These may affect up to 1 in 10 people:
a. itchy skin. b. local skin burning or pain Very rare side effects.
These may affect up to 1 in 10,000 people.
Use of Betnovate Scalp Application for a long period of time, or use under an airtight dressing, may cause the following symptoms:
c. increased weight. d. moon face / rounding of theface. e. obesity. f. skin thinning, this may cause stretch marks. g. skin wrinkling. h. skin dryness. i. the appearance of blood vessels under the surface of your skin. j. changes to the colour of yourskin. k. increased body hair
l. hair loss / lack of hair growth / damaged looking hair.
Other very rare skin reactions that may occur are:
m. allergic reaction at the site ofapplication. n. worsening of condition. o. application site irritation. p. redness. q. rash or hives. r. If you have psoriasis you may get raised bumps with pus under the skin. This can happen very rarely during or after treatment and is known as pustular psoriasis.
s. skin infection.
In children also look out for the following symptoms:
t. delayed weight gain
u. slow growth.
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-valerat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-valerat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 551)Lieferanten
| Firmenname |
Telefon |
E-Mail |
Land |
Produktkatalog |
Edge Rate |
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Nanjing Shizhou Biotechnology Co., Ltd
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+86-15850508050 +86-15850508050
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sean.lv@synzest.com |
China |
323 |
58 |
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Hebei Kangcang new material Technology Co., LTD
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+8615713292910
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Nancy@kangcang.com.cn |
China |
341 |
58 |
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Hebei Lingding Biotechnology Co., Ltd.
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+86-18031140164 +86-19933155420
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erin@hbldbiotech.com |
China |
58 |
58 |
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Hebei Mojin Biotechnology Co., Ltd
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+86 13288715578 +8613288715578
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sales@hbmojin.com |
China |
12835 |
58 |
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Hebei Chuanghai Biotechnology Co,.LTD
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+86-13131129325
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sales1@chuanghaibio.com |
China |
5889 |
58 |
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Wuhan Haorong Biotechnology Co.,ltd
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+86-18565342920; +8618565342920
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sales@chembj.net |
China |
289 |
58 |
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Henan Fengda Chemical Co., Ltd
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+86-371-86557731 +86-13613820652
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info@fdachem.com |
China |
20284 |
58 |
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Shaanxi TNJONE Pharmaceutical Co., Ltd
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+8618092446649
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sarah@tnjone.com |
China |
1143 |
58 |
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Frapp's ChemicalNFTZ Co., Ltd.
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+86 (576) 8169-6106
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sales@frappschem.com |
China |
880 |
50 |
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Beijing Cooperate Pharmaceutical Co.,Ltd
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010-60279497
|
sales01@cooperate-pharm.com |
CHINA |
1803 |
55 |
2152-44-5(9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-valerat)Verwandte Suche:
Dimagnesiumtrisiliciumoctaoxid
Beclometason
Trichlorethylen
Thiophanat-methyl
Pregna-1,4-dien-3,20-dion, 9-Fluor-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, Dinatriumsalz, (11β,16β)-
HT-2 TOXIN
Betamethason
Methyl
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat)
9-Chlor-11β-hydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-dipropionat
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-21-(hydrogenphosphonat)
17,21-Dihydroxy-16β-methylpregna-1,4,9(11)-trien-3,20-dion
Brommethan
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-di(valerat)
Fluor
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-valerat
- pregna-1,4-diene-3,20-dione,9-fluoro-11,21-dihydroxy-16-methyl-17-((1-oxopenty
- 9-fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-valerate
- 9ALPHA-FLUORO-16BETA-METHYLPREDNISOLONE 17-VALERATE
- 9ALPHA-FLUORO-16BETA-METHYL-11BETA,17ALPHA,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE 17-VALERATE
- 1,4-PREGNADIENE-11BETA,17ALPHA,21-TRIOL-9ALPHA-FLUORO-16BETA-METHYL-3,20-DIONE 17-VALERATE
- 1,4-pregnadiene-11b,17a,21-triol-9a-fluoro-16b-methyl-3,20-dione 17-valerate
- 9α-Fluoro-16β-methylprednisolone 17-valerate, Betnovate, 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 17-valerate, 1,4-Pregnadiene-11β,17α,21-triol-9α-fluoro-16β-methyl-3,20-dione 17-valerate
- BetaMethasone valerate (Betnovate)
- BetaMethasone Valerate, Micronized USP
- Deviphos
- Phosphanylidenezinc zinc
- Valison
- [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] pentanoate
- [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyethanoyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] pentanoate
- valeric acid [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-17-glycoloyl-11-hydroxy-3-keto-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] ester
- Betamethasone 17-valerate,1,4-Pregnadiene-11β,17α,21-triol-9α-fluoro-16β-methyl-3,20-dione 17-valerate, 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 17-valerate, 9α-Fluoro-16β
- Betamethasone Valerate (200 mg)
- Betamethasone Valerate (200 mg)K0C3300.997mg/mg(ai)
- Betamethasone 17-val
- BetaMethasone valerate (Betnovate, Celestone)
- (11β,16β)-9-Fluoro-11,21-dihydroxy-16-Methyl-17-[(1-oxopentyl)oxy]pregna-1,4-diene-3,20-dione
- 9α-Fluo
- 9α-Fluoro-16β-Methylprednisolone 17-Valerate
- (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-triMethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl pentanoate
- BetaMethasone valerate 17-
- betnovateat
- celestoderm
- 1,4-PREGNADIEN-9-ALPHA-FLUORO-16-BETA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 17-VALERATE
- BEDERMIN
- BETNESOL-V
- BETNEVAL
- BETAMETHASONE 17ALPHA-VALERATE
- BETAMETHASONE 17A-VALERATE
- BETAMETHASONE 17-VALERATE
- BETAMETHASONEVALERATE,MICRONIZEDPOWDER,USP
- 9α-Fluoro-11β,21-dihydroxy-16β-methyl-17α-valeryloxypregna-1,4-diene-3,20-dione
- Beta-Val
- Betoid
- Bextasol
- Celestan V
- Celestane V
- Celestoderm V
- Celeston valerate
- Dermosol
- Dermovaleas
- Ecoval 70
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16β-methyl-, 17-valerate (7CI, 8CI)
- Rinderon V
- Stanoval
- Tokuderm
- Valeric acid, 17-ester with 9-fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione (8CI)
- betamethasone pentanoate
- 1,4-pregnadiene-11β,17α,21-triol-9α-fluoro-16β-methyl-3,20-dione 17-valerate
- BETAMETHASONE 17-VALERATE VETRANAL, 250
- BETAMETHASONE 17-VALERATE BP USP
- BETAMETHASONE VALERATE BP STANDARD(CRM STANDARD)
- BETAMETHASONE VALERATE USP(CRM STANDARD)
- BETAMETHASONE VALERATE WHO(CRM STANDARD)
