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Dimagnesiumtrisiliciumoctaoxid

Magnesium trisilicate Struktur
14987-04-3
CAS-Nr.
14987-04-3
Bezeichnung:
Dimagnesiumtrisiliciumoctaoxid
Englisch Name:
Magnesium trisilicate
Synonyma:
dimagnesium trisilicon octaoxide;petimin;magnosil;三硅酸鎂生產(chǎn)廠家;meerschaum;dicarbocalm;Trisilicalm;trisilicate;parasepiolite;nesium trisiL
CBNumber:
CB8205317
Summenformel:
H8MgOSi
Molgewicht:
76.45
MOL-Datei:
14987-04-3.mol

Dimagnesiumtrisiliciumoctaoxid Eigenschaften

RTECS-Nr.
IN6620000
L?slichkeit
Practically insoluble in water and in ethanol (96 per cent).
Aggregatzustand
Powder
Farbe
White
Wasserl?slichkeit
insoluble H2O, EtOH [CRC10]
Merck 
14,5687
CAS Datenbank
14987-04-3(CAS DataBase Reference)
EPA chemische Informationen
Magnesium silicon oxide (Mg2Si3O8) (14987-04-3)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
WGK Germany  3
TSCA  Yes
Giftige Stoffe Daten 14987-04-3(Hazardous Substances Data)
Bildanzeige (GHS)
Alarmwort
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H413 Kann für Wasserorganismen sch?dlich sein, mit langfristiger Wirkung. Langfristig (chronisch) gew?ssergef?hrdend Kategorie 4
Sicherheit

Dimagnesiumtrisiliciumoctaoxid Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

The USP 32 describes magnesium trisilicate as a compound of magnesium oxide and silicon dioxide with varying proportions of water. It contains not less than 20.0% of magnesium oxide and not less than 45.0% of silicon dioxide. The PhEur 6.0 similarly describes magnesium trisilicate as having a variable composition corresponding to the approximate formula Mg2Si3O8·xH2O. It contains not less than 29.0% of magnesium oxide and not less than the equivalent of 65.0% of silicon dioxide, both calculated with reference to the ignited substance.
Magnesium trisilicate occurs as an odorless and tasteless, fine, white-colored powder that is free from grittiness.

Verwenden

Industrial odor absorbent, decolorizing agent, antioxidant, medicine (antacid).

Definition

USP specifies not less than 20% magnesium oxide and 45% SiO2, similar to the FCC requirements for magnesium silicate. See talc.

Vorbereitung Methode

Magnesium trisilicate may be prepared from sodium silicate and magnesium sulfate. It also occurs in nature as the minerals meerschaum, parasepiolite, and sepiolite.

Pharmazeutische Anwendungen

Magnesium trisilicate is used in oral pharmaceutical formulations and food products as a glidant. It is also used therapeutically as an antacid, and also for the treatment of ciprofloxacin overdose or toxicity.

Sicherheit(Safety)

Magnesium trisilicate is used in oral pharmaceutical formulations and is generally regarded as an essentially nontoxic and nonirritant material.
When administered orally, magnesium trisilicate is neutralized in the stomach to form magnesium chloride and silicon dioxide; some magnesium may be absorbed. Caution should be used when concentrations greater than 50 mEq of magnesium are given daily to persons with impaired renal function, owing to the risk of hypermagnesemia.
Therapeutically, up to about 2 g of magnesium trisilicate may be taken daily as an antacid. Reported adverse effects include the potential for osmotic diarrhea in the elderly using antacids containing magnesium trisilicate;and the potential for the formation of bladder and renal calculi following the long-term use of magnesium trisilicate as an antacid.

Lager

Magnesium trisilicate is stable if stored in a well-closed container in a cool, dry place.

Inkompatibilit?ten

Magnesium trisilicate, when taken with drugs such as mebeverine hydrochloride,proguanil,norfloxacin,sucralfate, and tetracycline, may cause a reduction in bioavailability via binding or chelation. The dissolution rate of folic acid, erythromycin stearate,paracetamol, and chloroquine phosphate may be retarded by adsorption onto magnesium trisilicate. Antimicrobial preservatives, such as the parabens, may be inactivated by the addition of magnesium trisilicate.
Magnesium trisilicate is also readily decomposed by mineral acids.

Regulatory Status

GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral tablets). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Dimagnesiumtrisiliciumoctaoxid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Dimagnesiumtrisiliciumoctaoxid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 423)Lieferanten
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Hebei Weibang Biotechnology Co., Ltd
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14987-04-3(Dimagnesiumtrisiliciumoctaoxid)Verwandte Suche:


  • dicarbocalm
  • magnesiummesotrisilicate
  • magnesiumsilicate(mg2si3o8)
  • DI-MAGNESIUM TRISILICATE
  • MAGNESII TRISILICAS
  • MAGNESIUM TRISILICATE
  • MAGNESIUM TRISILICATE HYDRATE, PH EUR
  • MAGNESIUM TRISILICATE BP
  • Matgnesium Trisilicate
  • di-Magnesium trisilicate, Magnesii trisilicas
  • magenesium trisilicate
  • Trisilicalm
  • Magnesium trisilicat
  • MagnesiuM Mesotrisillicate
  • Magnesiumsiliconoxide
  • magnesiumsiliconoxide(mg2si3o8)
  • magnesiumtrisilicateusp
  • magnosil
  • meerschaum
  • parasepiolite
  • petimin
  • silicicacid[h4si3o8],magnesiumsalt(1:2)
  • Medical grade MagnesiuM trisilicate
  • Three magnesium silicate
  • Magnesium trisilicate.5 H2O
  • nesium trisiL
  • Magnesium trisiL
  • Magnesium trisilicate USP/EP/BP
  • Sanguisuanmei
  • dimagnesium trisilicon octaoxide
  • fryed oil filter powder
  • Magnesium trisilicatehe
  • 三硅酸鎂生產(chǎn)廠家
  • NoKe Octadearyldimethylammoniumchloride
  • trisilicate
  • 14987-04-3
  • Mg2Si3O8
  • 2MgO3SiO2aq
  • 2MgO3SiO25H2O
  • MgOSi
  • Mg2O8Si3
  • H2Mg2O8Si3
  • Synthetic Reagents
  • Inorganic Salts
  • Halogenated Heterocycles ,Thiophenes
  • Pharmaceutical intermediates
  • Pharmaceutical intermediate
  • PHARMACEUTICALS
  • Inorganics
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