9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat)
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- CAS-Nr.
- 5593-20-4
- Bezeichnung:
- 9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat)
- Englisch Name:
- Betamethasone 17,21-dipropionate
- Synonyma:
- BETAMETHASONE DIPROPIONATE;BetaMethasone dipropionat;diprolene;diprosone;Betamethasone 17;S 3440;Psorion;Maxivate;diprosis;Diprophos
- CBNumber:
- CB3676725
- Summenformel:
- C28H37FO7
- Molgewicht:
- 504.6
- MOL-Datei:
- 5593-20-4.mol
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9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat) Eigenschaften
- Schmelzpunkt:
- 178 °C
- alpha
- D26 +65.7° (dioxane)
- Siedepunkt:
- 603.2±55.0 °C(Predicted)
- Dichte
- 1.1481 (estimate)
- Brechungsindex
- 69 ° (C=1, Dioxane)
- storage temp.
- 2-8°C
- L?slichkeit
- Practically insoluble in water, freely soluble in acetone and in methylene chloride, sparingly soluble in ethanol (96 per cent).
- Aggregatzustand
- Solid
- pka
- 12.87±0.70(Predicted)
- Farbe
- White to Pale Yellow
- Merck
- 1180
- InChIKey
- CIWBQSYVNNPZIQ-JCOVECCMSA-N
- SMILES
- C([C@]1([C@H](C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C)OC(=O)CC)(=O)COC(=O)CC |&1:1,2,4,6,16,18,20,23,r|
- CAS Datenbank
- 5593-20-4(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| S-S?tze: |
22-24/25 |
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| WGK Germany |
2 |
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| RTECS-Nr. |
TU4058000 |
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| HS Code |
29372290 |
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| Toxizit?t |
LD50 ipr-mus: 103 mg/kg NIIRDN 6,753,82 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H373 |
Kann die Organe sch?digen bei l?ngerer oder wiederholter Exposition. |
Spezifische Zielorgan-Toxizit?t (wiederholte Exposition) |
Kategorie 2 |
Warnung |
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P260, P314, P501 |
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| Sicherheit |
| P202 |
Vor Gebrauch alle Sicherheitshinweise lesen und verstehen. |
| P260 |
Dampf/Aerosol/Nebel nicht einatmen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P308+P313 |
BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
| P405 |
Unter Verschluss aufbewahren. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat) Chemische Eigenschaften,Einsatz,Produktion Methoden
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
Betamethasone 17,21-dipropionate is Pale Yellow Foam
Verwenden
Betamethasone 17,21-dipropionate is used as anti-inflammatory and antibacterial ointment for dermatosis.
Definition
Betamethasone 17,21-dipropionate is a steroid ester that is betamethasone in which the hydroxy hydrogens at positions 17 and 21 are replaced by propanoyl groups. It is used in combination with calcipotriene hydrate, a synthetic vitamin D analogue, for the topical treatment of plaque psoriasi in adult patients.
Sicherheitsprofil
Poison by subcutaneous andintraperitoneal routes. An experimental teratogen. Otherexperimental reproductive effects. When heated todecomposition it emits toxic fumes of F-.
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 431)Lieferanten
5593-20-4(9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat))Verwandte Suche:
Kresoxim-methyl
Methyl-4-hydroxybenzoat
Methylacrylat
Betamethason
Didodecyl-3,3'-thiodipropionat
Pregna-1,4-dien-3,20-dion, 9-Fluor-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, Dinatriumsalz, (11β,16β)-
Bensulfuron methyl
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-valerat
9β,11β-Epoxy-17,21-dihydroxy-16α-methylpregna-1,4-dien-3,20-dion
16α(R),17-[Butylidenbis(oxy)]-11β,21-dihydroxypregna-1,4-dien-3,20-dion
BETAMETHASONE DIPROPIONATE MM(CRM STANDARD)
Methyl
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-21-(hydrogenphosphonat)
17,21-Dihydroxy-16β-methylpregna-1,4,9(11)-trien-3,20-dion
9-Chlor-11β-hydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-dipropionat
Fluor
Brommethan
Propionsure
- BETAMETHASONE 17,21-DI-PROPIONATE
- BETAMETHASONE 17-ALPHA,21-DIPROPIONATE
- 1,4-PREGNADIEN-9-ALPHA-FLUORO-16-BETA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 17,21-DIPROPIONATE
- 9ALPHA-FLUORO-16BETA-METHYL-11BETA,17ALPHA,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE 17,21-DIPROPIONATE
- Betamethasonediproprionate
- 9--Fluoro-16--methyl-11,17,21-trihydroxy-1,4-pregnadiene-3,20-dione17,21-dipropionate
- BETANMETHASONE DIPROPIONATE
- BETAMETHASONEDIPROPIONATE,MICRONIZEDPOWDER,USP
- Diprophos
- Maxivate
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11β,16β)-
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16β-methyl-, 17,21-dipropionate (7CI, 8CI)
- Psorion
- Rinderon DP
- S 3440
- Sch 11460
- β-Methasone 17,21-dipropionate
- 9alpha-Fluoro-11beta,17alpha,21-trihydroxy-16beta-methyl-1,4-pregnadiene-3,20-dione 17,21-Dipropionate
- 17,21-Di(propionyloxy)-9-fluoro-11β-hydroxy-16β-methylpregna-1,4-diene-3,20-dione
- [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
- [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyethanoyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
- propionic acid [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-3-keto-10,13,16-trimethyl-17-(2-propionyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] ester
- Betamethasone 17,21-dipropionate,9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 17,21-dipropionate
- Betamethasone Dipropionate (125 mg)
- Betamethasone 17,21-
- 9a-fluoro-16b-methyl-11b,17a,21-trihydroxy-1,4-pregnadiene-3,20-dione 17,21-dipropionate
- Betamethasone dipropionate for peak identification
- Betamethasone dipropionate for system suitability
- 17,21 betaMethasone dipropionate ester
- diproderm
- diprosis
- 9-fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-di(propionate)
- Betanmethasone Dipronate
- Pregna-1,4-Diene-3,20-Dione,9-Fluoro-11-Hydroxy-16-Methyl-17,21-Bis(1-Oxopropoxy)-,(11Beta,16Beta)-
- (11-beta,16-beta)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione-17,21-dipropionate
- Betamethaasone Dipropionate
- 99% High Purity Raw Powder Betamethason 17, 21-Dipropionate CAS 5593-20-4
- Betamethasone dipropionate (B1040000)Q: What is
Betamethasone dipropionate (B1040000) Q: What is the CAS Number of
Betamethasone dipropionate (B1040000)
- Betamethasone dipropionate for peak identification (Y0001416)
- Betamethasone dipropionate for system suitability A (Y0001925)
- Betamethasone DipropionateQ: What is
Betamethasone Dipropionate Q: What is the CAS Number of
Betamethasone Dipropionate Q: What is the storage condition of
Betamethasone Dipropionate
- Betamethasone Dipropionate (1067704)
- AT-13387 lactate
- ATI-13387A
- ATI-13387AU
- propanoic acid [2-[(8R,9S,10R,11S,13S,14R,16S,17R)-8-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(1-oxopropoxy)-6,7,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] ester
- Betamethasone 17,21-dipropionate, ≥97.0%
- Betamethasone 17,21-dipropionate(5593-20-4)
- Betamethasone dipropionate for peak identification CRS
- Betamethasone 17,21-Dipropionate >
- Betamethasone dipropionate CRS
- Diprolene AF
- Betamethasone dipropionate for system suitability A
- (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-(propionyloxy)acetyl)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate
- Anhydrous Beclometasone Dipropionate
- Betamethasone dipropionate solution in Acetonitrile, 100μg/mL
- Pregna-1,4-diene-3,20-dione,9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11b,16b)-
- Betamethasone 17,21-dipropionate USP/EP/BP
