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Dulaglutide

Dulaglutide Struktur
923950-08-7
CAS-Nr.
923950-08-7
Englisch Name:
Dulaglutide
Synonyma:
LY2189265);Dulaglutide;Dulaglutide USP/EP/BP;Dulaglutide (Trulicity;Dulaglutide(LY2189265);Dulaglutide(sodium salt);Research Grade Dulaglutide;Dulaglutide - solution in PBS;Research Grade Dulaglutide(DHE40129)
CBNumber:
CB12738186
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

Dulaglutide Eigenschaften

Aggregatzustand
Liquid
Farbe
Colorless to light yellow
CAS Datenbank
923950-08-7

Sicherheit

Giftige Stoffe Daten 923950-08-7(Hazardous Substances Data)

Dulaglutide Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Dulaglutide, a GLP-1 receptor agonist that is administered subcutaneously once weekly, has been approved since 2014 for the treatment of adults with type 2 diabetes. 

Trademarks

Dulaglutide is marketed by Eli Lilly as Trulicity.

Mechanism of action

The dulaglutide mechanism of action involves activation of the GLP-1 receptor, a membrane-bound cell-surface receptor coupled to adenylyl cyclase in b cells. Thus, it increases intracellular cyclic AMP in these cells, leading to a glucose-dependent release of insulin. Dulaglutide also reduces secretion of glucagon and slows gastric emptying.

Mode of action

The mechanism of action of dulaglutide is as a Glucagon-like Peptide-1 (GLP-1) Agonist. Structurally, dulaglutide is made by replacing Ala with Gly at position 8, Glu with Gly at position 22, and Arg with Gly at position 36 on the GLP-1 (7-37) chain, with an average biological half-life of up to 90h.

Dulaglutide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Dulaglutide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 137)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618092446649
sarah@tnjone.com China 1143 58
Shanghai Minbiotech Co., Ltd.
+8617315815539
sales@minbiotech.com CHINA 129 58
BOC Sciences
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inquiry@bocsci.com United States 19553 58
Wuhan Quanjinci New Material Co.,Ltd.
+86-15271838296; +8615271838296
kyra@quanjinci.com China 1512 58
Zhejiang Hangyu API Co., Ltd
+8617531972939
anna@api-made.com China 2943 58
Shanghai Yunao International Trade Co., Ltd
+8617621705551
asdf@shanghaihg.cn China 264 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325
sales1@chuanghaibio.com China 5893 58
Wuhan Cell Pharmaceutical Co., Ltd
+86-13129979210 +86-13129979210
sales@cellwh.com China 376 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8617865335152
Mandy@hangyubiotech.com China 10986 58
Nantong Guangyuan Chemicl Co,Ltd
+undefined17712220823
admin@guyunchem.com China 615 58

  • Dulaglutide - solution in PBS
  • Dulaglutide USP/EP/BP
  • Dulaglutide
  • Research Grade Dulaglutide(DHE40129)
  • Research Grade Dulaglutide
  • Dulaglutide (Trulicity
  • LY2189265)
  • Dulaglutide(sodium salt)
  • Dulaglutide(LY2189265)
  • 923950-08-7
  • GLP
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