1,4:3,6-Dianhydro-D-glucitol
CAS-Nr.
652-67-5
Bezeichnung:
1,4:3,6-Dianhydro-D-glucitol
Englisch Name:
Isosorbide
Synonyma:
(3R,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diol;at101;IsMotic;Isosorbide (75% solution, 1 g);ucitoL;isobide;hydronol;Isosorbid;NSC 40725;devicoran
CBNumber:
CB1162705
Summenformel:
C6H10O4
Molgewicht:
146.14
MOL-Datei:
652-67-5.mol
1,4:3,6-Dianhydro-D-glucitol Eigenschaften
Schmelzpunkt:
60-63 °C (lit.)
Siedepunkt:
175°C/2mmHg(lit.)
alpha
42 º (c=3, H2O)
Dichte
1.0945 (rough estimate)
Dampfdruck
0.007Pa at 20℃
Brechungsindex
45 ° (C=5, H2O)
storage temp.
Inert atmosphere,Room Temperature
L?slichkeit
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
pka
13.17±0.40(Predicted)
Aggregatzustand
Crystals, Crystalline Solid or Mass
Farbe
Off-white to light yellow or beige
Optische Aktivit?t
[α]20/D +45.2°, c = 3 in H2O
Wasserl?slichkeit
Soluble in alcohols, water and ketones.
Sensitive
Hygroscopic
Merck
14,5224
BRN
80510
InChIKey
KLDXJTOLSGUMSJ-JGWLITMVSA-N
LogP
-1.39 at 20℃
CAS Datenbank
652-67-5(CAS DataBase Reference)
EPA chemische Informationen
D-Glucitol, 1,4:3,6-dianhydro- (652-67-5)
Sicherheit
Risiko- und Sicherheitserkl?rung
Gefahreninformationscode (GHS)
Bildanzeige (GHS)
Alarmwort
Warnung
Gefahrenhinweise
Code
Gefahrenhinweise
Gefahrenklasse
Abteilung
Alarmwort
Symbol
P-Code
H227
Combustible liquid
Flammable liquids
Category 4
Warnung
P210, P280, P370+P378, P403+P235,P501
Sicherheit
P210
Von Hitze, hei?en Oberfl?chen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen.
P280
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P370+P378
Bei Brand: zum L?schen verwenden.
P403+P235
An einem gut belüfteten Ort aufbewahren. Kühl halten.
P501
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.
1,4:3,6-Dianhydro-D-glucitol Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
S-S?tze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
off-white to light yellow or beige crystals,
Verwenden
Isosorbide is a reagent widely used to prepare detergents, cleansers, cosmetics, agrochemicals and vasodilators.
Definition
A polyol with a hydroxyl group attached to each of
two cis-oriented saturated furan rings. Intermediate
for pharmaceuticals. Combustible.
Biologische Funktion
emergency treatment of acute angle-closure glaucoma.
It should not be confused with isosorbide dinitrate, an
antianginal drug.
Clinical Use
Isosorbide is basically a bicyclic form of sorbitol that is used orally to cause a reduction in intraocular pressure in glaucoma cases. Although a diuretic effect is noted, its
ophthalmologic properties are its primary value.
1,4:3,6-Dianhydro-D-glucitol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol
D-Iditol, 2,5-anhydro-
Hexitol, 2,5-anhydro-
Octa-1,3,7-trien
Tetrahydrofuran
2,2-DIMETHYL-4-(2-OXIRANYL)TETRAHYDROFURO[3,4-D][1,3]DIOXOLE
Isosorbidmononitrat
1,4:3,6-Dianhydro-D-glucitol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 453)Lieferanten
Americas 1
Belgium 4
Canada 2
China 346
Europe 4
Germany 11
India 18
Japan 4
Malaysia 1
Singapore 2
Slovakia 1
South Korea 1
Spain 2
Switzerland 6
The Netherlands 2
Ukraine 1
United Kingdom 12
United States 35
Global 453
652-67-5(1,4:3,6-Dianhydro-D-glucitol)Verwandte Suche:
D-Glucitol
Isosorbiddinitrat
Glucose
1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol
Diammoniumcarbonat
1,4:3,6-Dianhydro-D-glucitol-2-nitrat
1,4:3,6-Dianhydro-D-glucitol-2-acetat
Isosorbidmononitrat
1,4-Anhydro-D-glucitol
Isononylalkohol
Isooctadecansure
Isoamylalkohol
Alkohole, C11-14-Iso-, C13-reich
Kalium-2-ethylhexanoat
3-Methyl-2-buten-1-ol
Isovalerylchlorid
3-Methylbutan-1-thiol
Triethoxy(3-isocyanatopropyl)silan
Dianhydro-D-glucitol 98%
1,4:3,6-DIANHYDRO-D-SORBITOL
1,4:3,6-DIANHYDROGLUCITOL
1,4:3,6-DIANHYDROSORBITOL
1,4:3,6-DIANHYDRO-D-GLUCITOL
D-ISOSORBIDE
DIANHYDRO-D-GLUCITOL
DIANHYDRO-D-SORBITOL
ISOSORBIDE
(3S,3AR,6R,6AR)-HEXAHYDRO-FURO[3,2-B]FURAN-3,6-DIOL
1,4:3,6-dianhydro-d-glucito
Isosorbide, typically 98%
1,4:3,6-Dianhydro-D-sorbitol, D-Isosorbide
Isosorbide,98%
Dianhydro-D-glucitol,1,4:3,6-Dianhydro-D-sorbitol, D-Isosorbide
Isosorbide, 98% 100GR
1,4:3,6-Dianhydroglucitol
1,4:3,6-Dianhydrosorbitol
1,4,3,6,5-Dianhydrosorbitol
ISOSONBIDE(1,4:3,6-DIANHYDRO-D-SORHITOL)
Isosorbid
D-Glucitol, 1,4:3,6-dianhydro-
D-Glucitol, 1,4:3,6-dianhydro- (9CI)
NSC 40725
1,4,3,6-DIANHYDRO-D-GLUCITOL D-ISOSORBIDE
4:3,6-dianhydro-d-glucito
d-1,4:3,6-dianhydroglucitol
devicoran
hydronol
isobide
Isosorbide,typically98%
Isosorbide Isosorbide
Isosorbide>
Isosorbide, 97%, reagent grade
Dianhydro-D-g
ucitoL
Dianhydro-D-gL
Isosorbide USP/EP/BP
Isosorbide Impurity 21
Isosorbide Impurity 22
IsosorbideQ: What is
Isosorbide Q: What is the CAS Number of
Isosorbide Q: What is the storage condition of
Isosorbide Q: What are the applications of
Isosorbide
Isosorbide (75% solution, 1 g) (1352008)
Isosorbide (75% solution, 1 g)
IsMotic
(3R,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diol
at101
1,4:3,6-dianhydro-D-[UL-13C6]glucitol
Isosorbitol
(3S, 3AR, 6R, 6AR) - Hexahydrogen - [3,2-B] furan-3,6-diol)
Isosorbide
1,4:3,6-Dianhydro-D-glucitol
Isosorbide in Acetonitrile
lsosorbide
652-67-5
662-67-5
Carbohydrate Synthesis
Specialty Synthesis
Monosaccharides
Carbohydrates & Derivatives
Heterocycles