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90776-59-3

中文名稱 雜氮雙環(huán)磷酸酯
英文名稱 beta-Methyl vinyl phosphate (MAP)
CAS 90776-59-3
分子式 C29H27N2O10P
MDL 編號 MFCD01318092
分子量 594.51
MOL 文件 90776-59-3.mol
更新日期 2024/12/20 09:16:40
90776-59-3 結構式 90776-59-3 結構式

基本信息

中文別名
[4R-[4a,5b,6b(R*)]]-3-二苯基磷酰氧基-6-(1-羥基乙基)-4-甲基-7-氧代-1-氮雜雙環(huán)[3.2.0]庚-2-烯-2-羧酸對硝基芐酯
1b-甲基碳青霉烯雙環(huán)母核 (MAP)
美羅培南主環(huán)
雜氮雙環(huán)磷酸酯
美羅培南中間體Ⅰ
1b-甲基碳青霉烯雙環(huán)母核(MAP)
比阿培南等培南類主環(huán)
1Β-甲基碳青霉烯雙環(huán)母核
1-氮雜雙環(huán)[3.2.0]庚-2-烯-2-羧酸,3-[(二苯氧基氧膦基
1B-甲基碳青霉烯雙環(huán)母核
美羅培南雙環(huán)母核
1-氮雜雙環(huán)[3.2.0]庚-2-烯-2-羧酸,3-[(二苯氧基氧膦基)氧]-6-[(1R)-1-羥乙基]-4-甲基-7-氧代,(4-硝基苯基)甲酯,(4R,5R,6S)-
英文別名
3-(DIPHENOXY-PHOSPHORYLOXY)-6-(1-HYDROXY-ETHYL)-4-METHYL-7-OXO-1-AZA-BICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID 4-NITRO-BENZYL ESTER
4-NITROBENZYL (1R,5R,6S)-6-[(1R)-1-HYDROXYETHYL]-2-[(DIPHENYLPHOSPHONO)OXY]-1-METHYLCARBAPEN-2-EM-3-CARBOXYLATE
4-NITROBENZYL-(1R,5R,6S)-6-[(1R)-1-HYDROXYETHYL]-2-[(DIPHENYLPHOSPHONO)OXY]-1-METHYLCARBAPEN-2-EM-3-CARBOXYLIC ACID
(4r,5s,6s)-3-(diphenyloxy)phosphoryloxy-6-[(1r)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3,2,0]hept-2-ene-2-carboxylate
beta-Methyl vinyl phosphate (MAP)
p-nitrobenzyl (1r,5r,6s)-6-[(1r)-1-hydroxyethyl]-2-
P-NITROBENZYL (1R,5R,6S)-6-[(1R)-1-HYDROXYETHYL]-2-[(DIPHENYLPHOSPHONO)OXY]-1-METHYLCARBAPEN-2-EM-3-CARBOXYLATE
P-NITROBENZYL (1R,5R,6S)-6-[(1R)-HYDROXY ETHYL]-2-[(DIPHENYLPHOSPHONO)OXY]-1-METHYL CARBAPEN-2EM-3-CARBOXYLATE
PNB(4R,5S,6S)-3-(diphenyl-oxy)phosphoryloxy-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3,2,0]hept-2-ene-2-carboxylate
β-METHYL VINYL PHOSPHATE(MAP)
1B-methyl vinyl phosphate
1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylicacid,3-[(diphenoxyphosphinyl)oxy]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-,(4-nitrophenyl)methyl ester,(4R,5R,6S)-
MVP
MAP Or MVP
P-Nitrobenzyl (1r,5r,6s)-6-[(1r)-1-Hydroxyethyl]-2-[(Diphenylphosphono)Oxy]-1-Methylcarbapen-2-Em-3-Carboxylate
3-(DIPHENOXY-PHOSPHORYLOXY)-6-(1-HYDROXY-ETHYL)-4-METHYL-7-OXO-1-AZA-BICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID 4-NITRO-BENZYL ESTER
BETA-METHYL VINYL PHOSPHATE
1B-MethylVinylPhosphate(MapOrMvp)(ForMeropenem)
4-Nitrobenzyl-(1R,5R,6S)-6-[(1R)-1-hydroxyethyl]-2-[(diphenylphosphono)oxy]-1-methylcarbapen-2-em-3-ca
4-Nitrobenzyl-(1R,5R,6S)-6-[(1R)-1-hydroxyethyl]-2-[(diphenylphosphono)oxy]-1-methylcarbapen-2-em-3-carboxylic acid

物理化學性質

熔點129-131?C
沸點722.4±60.0 °C(Predicted)
密度1.47±0.1 g/cm3(Predicted)
儲存條件Sealed in dry,2-8°C
溶解度可溶于氯仿(少許)、甲醇(少許)
酸度系數(pKa)14.36±0.20(Predicted)
形態(tài)固體
顏色白色至灰白色

安全數據

危險性符號(GHS)GHS hazard pictograms
GHS07
警示詞警告
危險性描述H302-H315-H319-H335

常見問題列表

簡介
雜氮雙環(huán)磷酸酯為白色結晶(針狀)粉末狀,用作醫(yī)藥中間體,可用于制備替比培南匹伏酯。
用途
雜氮雙環(huán)磷酸酯是一種醫(yī)藥中間體,可用于制備替比培南匹伏酯。
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