70209-81-3
中文名稱
伊維菌素B1B
英文名稱
Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-
CAS
70209-81-3
分子式
C47H72O14
分子量
861.07
MOL 文件
70209-81-3.mol
更新日期
2024/10/11 11:28:06
70209-81-3 結(jié)構(gòu)式
基本信息
中文別名
伊維菌素雜質(zhì)2依維菌素B1B
伊維菌素B1B
英文別名
Component B1bIvermectin B1b
IvermectinH2B1b
avermectin H2B1b
Dihydroavermectin B1b
22,23-Dihydroavermectin B1b
22,23- dihydroavermectin B1b (Ivermectin B1b)
22,23-Dihydro-34-nor-5-O-demethylavermectin A1a
DihydroaverMectin B1b, 22,23-DihydroaverMectin B1b
22,23-Dihydro-5-O-demethyl-25-de(1-methylpropyl)-25-isopropylavermectin A1a
物理化學(xué)性質(zhì)
沸點934.1±65.0 °C(Predicted)
密度1.24±0.1 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
酸度系數(shù)(pKa)12.42±0.70(Predicted)
形態(tài)固體
穩(wěn)定性對溫度敏感
伊維菌素B1B價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2024/11/08 | HY-125729 | 伊維菌素B1B Ivermectin B1b | 70209-81-3 | 500μg | 6570元 |
常見問題列表
生物活性
Ivermectin B1b 是 Ivermectin 的次要成分。Ivermectin 是一種有效的抗寄生蟲藥物，可抑制 SARS-CoV-2 復(fù)制。體外研究
Ivermectin and Ivermectin B1b are the most potent inhibitors of contraction and motility in both susceptible isolates (
H. contortus
McMaster and and
O. circumcincta
McMaster) also show the highest resistance ratios in both species.
Vermectin is a macrocyclic lactone that acts as a positive allosteric modulator of α7 nicotinic acetylcholine receptors (nAChRs) but has no modulatory activity on 5-HT3 receptors.
體內(nèi)研究
Ivermectin B1b causes snail death.