133524-69-3
中文名稱(chēng)
N-DEBOC-DOCETAXEL
英文名稱(chēng)
N-Deboc-Docetaxel
CAS
133524-69-3
分子式
C38H45NO12
分子量
707.76
更新日期
2024/08/23 09:07:10
基本信息
中文別名
多西他賽衍生物多西他賽雜質(zhì)11
多西紫杉醇雜質(zhì)19
N-脫BOC多西他賽
多西原料脫BOC產(chǎn)物
N-脫BOC多西他賽等
N-DESBOC多西他賽
10-去乙?；?N-去苯甲?；仙即?/span>
英文別名
N-Deboc-DocetaxelN-DesBoc Docetaxel
Docetaxel Impurity 40
N-Debenzoyl-10-deacetylpaclitaxel
10-Desacetyl-N-debenzoylpaclitaxel
N-De(tert-butoxycarbonyl)-10-deacetyldocetaxel
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-amino-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-ylbenzoate
Docetaxel impurity 3/N-DesBoc Docetaxel/10-Desacetyl-N-debenzoylpaclitaxel/(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-amino-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12
Benzenepropanoic acid, β-amino-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
物理化學(xué)性質(zhì)
熔點(diǎn)>150°C (dec.)
沸點(diǎn)846.0±65.0 °C(Predicted)
密度1.41±0.1 g/cm3(Predicted)
儲(chǔ)存條件Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度可溶于氯仿（少許）、甲醇（少許）
酸度系數(shù)(pKa)10.19±0.45(Predicted)
形態(tài)固體
顏色白色至灰白色
穩(wěn)定性吸濕性
