126-27-2
中文名稱
奧昔卡因
英文名稱
Oxethazaine
CAS
126-27-2
EINECS 編號(hào)
204-780-5
分子式
C28H41N3O3
MDL 編號(hào)
MFCD00079202
分子量
467.64
MOL 文件
126-27-2.mol
更新日期
2024/07/15 17:11:01
126-27-2 結(jié)構(gòu)式
基本信息
中文別名
2-雙(N-甲基-N-苯基叔丁基-氨基甲酰甲基)氨基乙醇奧昔卡因
阿塞賽因
奧西卡因
羥乙卡因
英文別名
2-di(n-methyl-n-phenyl-tert-butyl-carbamoylmethyl)aminoethanol2-HYDROXYETHYLIMINOBIS-[N-(ALPHA,ALPHA-DIMETHYLPHENETHYL)-N-METHYLACETAMIDE]
OXETACAINE
OXETHAZAINE
OXETHAZINE
2,2’-((2-hydroxyethyl)imino)bis(n-(1,1-dimethyl-2-phenylethyl)-n-methylaceta
2,2’-((2-hydroxyethyl)imino)bis(n-(alpha,alpha-dimethylphenethyl)-n-acetamid
2,2’-((2-hydroxyethyl)imino)bis(n-(alpha,alpha-dimethylphenethyl)-n-methylac
acetamide,2,2’-(2-hydroxyethyl)imino)bis(n-(1,1-dimethylphenylethyl)-n-methy
betalgil
fh099
mucaine
mucoxin
mutesa
muthesa
n,n-bis(n-methyl-n-phenyl-tert-butylacetamido)-beta-hydroxyethylamine
oxaine
oxethacaina
oxethacaine
stomacain
所屬類(lèi)別
分析化學(xué)：法醫(yī)和獸醫(yī)標(biāo)準(zhǔn)品物理化學(xué)性質(zhì)
熔點(diǎn)104-105°C
沸點(diǎn)570.1°C (rough estimate)
密度1.0974 (rough estimate)
折射率1.7800 (estimate)
儲(chǔ)存條件Refrigerator
溶解度幾乎不溶于水；易溶于甲醇；溶于乙酸乙酯。
酸度系數(shù)(pKa)14.62±0.10(Predicted)
形態(tài)neat
顏色白色至灰白色
水溶解性<0.1 g/100 mL at 23 ºC
CAS 數(shù)據(jù)庫(kù)126-27-2(CAS DataBase Reference)
EPA化學(xué)物質(zhì)信息Oxethazaine (126-27-2)
常見(jiàn)問(wèn)題列表
生物活性
Oxethazaine (Oxetacaine) 是芬特明的酸性前體，是一種具有耐酸性和口服活性的鎮(zhèn)痛試劑。Oxethazaine (Oxetacaine) 具有緩解消化性潰瘍疾病或食管炎引起的疼痛的潛力。體內(nèi)研究
Oxetacaine (intraperitoneal?injection; 5, 10, and 15 mg/kg; during days 4–11) doses induces significant conditioned place preference (CPP), and there are no differences among the groups. While its postive control group phentermine only 3 mg/kg causes significant CPP..
| Animal Model: | Male Wistar rats |
| Dosage: | 5, 10, and 15 mg/kg; during days 4–11 |
| Administration: | Intraperitoneal?injection |
| Result: | Showed a significant CPP in vivo. |